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The introduction of a system that would improve a manager’s ability to successfully supervise their employees, operating companies has been identified as a solution

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báo cáo khoa học: " Retailers’ knowledge of tobacco harm reduction following the introduction of a new brand of smokeless tobacco" pps

... of tobacco harm reduction following the introduction of a new brand of smokeless tobacco Harm Reduction Journal 2010 7:18 Submit your next manuscript to BioMed Central and take full advantage of: ... brochure and the four alternating federally mandated warnings that take up half of the front of the dMS packages Heavner et al Harm Reduction Journal 2010, 7:18 http://www.harmreductionjournal.com/content/7/1/18 ... researchers, aged 20 and 21 were trained to approach the retailers, ask questions about THR as part of a conversation about dMS, and attempt to purchase dMS The dMS refrigerator was often near the cash...
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Báo cáo y học: "The use of a blood conservation device to reduce red blood cell transfusion requirements: a before and after study" doc

... least 0.05 unit PRBC/patient/day with a standard deviation of 0.15 units PRBC/patient/day Statistical analysis We expressed variables as means ± standard deviations and numbers (percentages), and ... extends far beyond apparent cost-benefit ratio and economic savings PRBC transfusions are associated with significant morbidity and mortality and any reduction in transfusions may eventually improve ... preservation of Hb, it is logical that use of such a device will reduce transfusion requirements In this beforeand -after study, use of a blood conservation device in the presence of a restrictive transfusion...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 1 ppsx

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 1 ppsx

... A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS Second Edition Phillip I Good, Ph.D A JOHN WILEY & ... Maintaining an Audit Trail 15 7 Security 15 7 For Further Information 15 8 12 Are You Ready? 16 1 Pharmaceuticals/Devices 16 1 Software 16 2 Hardware 16 2 Documentation 16 2 Investigators 16 2 External Laboratories ... the Trials 18 6 Budgets and Expenditures 18 6 For Further Information 18 7 15 Data Analysis 18 9 Report Coverage 18 9 Understanding Data 19 0 Categories 19 0 Metric Data 19 2 Statistical Analysis 19 4 Categorical...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 2 pps

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 2 pps

... beyond an understanding of the data management software to security (maintaining onsite and offsite backups) and quality control Programs for Data Analysis Development of programs for data analysis ... conflicts The lead software developer need not be a member of the programming team, but she must possess a general knowledge of both data entry and data management software and be able to prepare and ... data you don’t need Store and analyze the data you collect DO Steps C–F can be executed in parallel C Obtain Regulatory Agency Approval for the Trials Obtaining regulatory agency approval can...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 3 pps

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 3 pps

... 58 PART I PLAN trials are completed and the data analyzed, there is no rational basis for other than a random assignment Warning: An investigator who has strong feelings for or against a particular ... for the study the patients, the manner in which the treatment is administered, the manner in which the observations are obtained, the apparatus used to make A Manager’s Guide to the Design and Conduct ... possible to reach a final conclusion (at least one acceptable to the regulatory agency) until all the data are in, there may be sufficient evidence at an earlier stage to launch a second broader set of...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 4 potx

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 4 potx

... crossover trials are contemplated, a pharmacokineticist is an essential addition to the design team To maintain the validity of a fractional factorial design one has to be able to assume that the effect ... was the lack of commercially available software with which to design the experiment and perform the analysis Fortunately, S+SeqTrial and EAST are now available (see Appendix) TAKING COST INTO ... demonstrating the one may be far too small to establish the other The chief advantage of crossover and fractional factorial designs—reduction in sample size—is lost, while their disadvantages remain...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 5 potx

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 5 potx

... days and months and weeks the patient was counted as having BR Otherwise, a follow-up angiogram of the target lesion at ± 0 .5 months was used If such an angiogram was not available, the first angiogram ... only with smaller studies of more limited scope Industry-sponsored trials often entail a 3 0- to 50 -page protocol in contrast to the 5- to 10-page protocols common in the academic area, and industry ... weeks CANDAs eliminate much of this delay By employing computer-assisted data entry you are automatically in a position to submit a CANDA Between 1991 and 1994, CANDAs in the United States were approved...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 6 pdf

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 6 pdf

... spell of a salesperson) Three issues are discussed: Choice of data management software and the options available to you Transfer of data from data entry to data storage and from data storage to ... inventors of the relational database is that SQL, the query language associated with System R, IBM’s first attempt at a relational database, has become a standardized part of all relational software, ... Hierarchical Databases The traditional answer to some of these issues was the hierarchical database model A hierarchical database is a series of flat files, each one similar to a spreadsheet, that...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 7 pot

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 7 pot

... review them Manufacturing Project manager, software manager, and data manager Cross-functional review and approval by biostatistics, CRMs, and medical affairs Design team, medical manager, and medical ... three ways: Enter directly at each physician’s computer Transfer the data automatically at day’s end via telephone to the central database Copy the data each day to a CD; at the end of the week the ... your approval Thereafter, all decisions as to access to the data will be yours alone Maintaining an Audit Trail To avoid even the appearance of fraud, and to satisfy government regulations, all...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 8 pot

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 8 pot

... for cofactors The second part of Table 15.5 reveals the statistically significant relation of survival to the Karnofsky Index, which is a measure of the overall status of the cancer patient at the ... data have often been analyzed by chi-square methods as well But a chi-square analysis is really a multisided test designed to detect any and all alternatives to the null hypothesis rather than ... fees to investigators, travel monies, and the cost of computer hardware and over -the- counter software 39 A multivariate statistical analysis may be appropriate; see Pesarin (2001) 186 PART II...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 9 doc

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 9 doc

... CHAPTER 15 DATA ANALYSIS 211 With the large samples that characterize long-term trials, the use of the bootstrap is always preferable When we bootstrap, we treat the original sample as a stand-in ... from the sample in hand to a larger population, the samples must be taken at random from and be representative of that population.48 An examination of surgical procedures and of those characteristics ... CHAPTER 15 DATA ANALYSIS 2 19 Dmitrienko A, Molenberghs G, Chuang-Stein C, Offen W (2005) Analysis of Clinical Trials Using SAS: A Practical Guide SAS Publishing Donegani M ( 199 1) An adaptive and powerful...
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A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 10 potx

A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS - PART 10 potx

... initial analysis of the data showed that E offered no particular advantage over A Probing deeper, it was found that when abixcimab, an adjunct given some of the patients, was taken into account, ... Let the software determine your hardware Good (1984) An extremely wide choice of software is available to ease your task of designing, managing, and analyzing clinical trials Some programs offer ... Manager’s Guide to the Design and Conduct of Clinical Trials, by Phillip I Good Copyright ©2006 John Wiley & Sons, Inc APPENDIX SOFTWARE 237 Oracle Clinical Has the standard features of Oracle Automatically...
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Study on corporate governance index of Vietnam commercial bank –  the case of a newly established, medium to large  joint stock commercial ban

Study on corporate governance index of Vietnam commercial bank – the case of a newly established, medium to large joint stock commercial ban

... influenced by the management style of a market economy after privatization The bank is a medium to large joint stock commercial banks in Vietnam For these reasons, corporate governance of the bank is ... out of 44 Vietnam banks - Its performance (ROA) ranked among top 20 banks Secondary information and data of the bank includes the bank annual report, audited financial reports, reports and other ... individual and institutional investors If the bank has intention and plan to go listed (For unlisted banks) If the bank has plan to be listed on international market The benchmark of proportion of shares...
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