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Design, optimization and structure activity relationship study of CD2 derived peptides for immunomodulation

Design, optimization and structure activity relationship study of CD2 derived peptides for immunomodulation

Design, optimization and structure activity relationship study of CD2 derived peptides for immunomodulation

... domain of CD2 and CD58 (a) Crystal structure of rCD2 D1 [30] (b) human CD2 D1[27, 33] and (c) NMR structure of CD58 D1 with mutations [33, 34] 1.3.2 CD2 ligands and ligand binding sites The first CD2 ... Targeting CD2/ CD58 interaction for immunomodulation 14 1.3.1 CD2 structure 15 1.3.2 CD2 ligands and ligand binding sites 16 1.3.3 Properties of CD2- ligand interactions 17 1.3.4 Structural basis for CD2- ligand ... 1.3.3 Properties of CD2- ligand interactions The interaction of CD2 and its ligands is characterized by relatively low affinity (kd=10-20µΜ for hCD2-CD58 and kd=60-90µΜ for rCD2-CD48) that is...
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Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc

Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc

... between the base adenine (or hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, ... Regulation of calcium signalling by the second messenger cyclic adenosine diphosphoribose (cADPR) Curr Mol Medical 4, 239–248 16 Guse AH (2004) Biochemistry, biology, and pharmacology of cyclic adenosine ... situation is unique for the northern ribose since replacement of the oxygen by a carbocyclic bridge in the southern ribose in the molecule termed cyclic aristeromycin diphosphoribose (cArisDPR,...
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ho and wong - 2001 - a study of the relationship between cg structure and the extent of voluntary disclosure

ho and wong - 2001 - a study of the relationship between cg structure and the extent of voluntary disclosure

... as there is considerable variation in the measures of the explanatory and dependent variables Last but not the least, as the study found that the audit committee and family control are significant ... 0.25 average number of IND is 2.45 On the other hand, the average percentage of family members sitting on the board was 32.1% Table shows that in 29% of the sample companies the chairman was also ... directors and total financial disclosure (mandatory and voluntary) was weaker for family-controlled firms Although the situation where family members dominate the board is not as common in Hong Kong as...
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Relationship between customer satisfaction and service quality a study of three service sectors

Relationship between customer satisfaction and service quality a study of three service sectors

... dimensions quality Service quality and Service quality dimensions Service quality Service dimensions quality Service quality and Customer satisfaction Customer satisfaction Service quality Following ... The relationship between customer satisfaction and Service quality for this study If customers agree that they are satisfied and give the reasons for satisfaction as service quality; service quality ... precise about the meaning and measurements of satisfaction and service quality Satisfaction and service quality have certain things in common, but satisfaction generally is a broader concept, whereas...
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Multi target selection and high throughput quantitative structure activity relationship model development

Multi target selection and high throughput quantitative structure activity relationship model development

... trial multi- target drugs against the same diseases.20 Table 1.1 Literature reported multi- target drugs, targeted diseases, potencies against individual targets and cell-lines, and multi- target ... to multi- targeted cancer therapy 1.1.1 From single- to multi- targeted cancer therapy 1.1.2 Multi- target molecular scaffolds 1.1.3 Proposed prospect of multi- target selection ... analogues a and b of scaffold A, and analogues b and c of scaffold B show markedly different pIC50 values (activity cliff) These and other multi- target scaffolds appear to be the backbone of multi- target...
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Design, optimization and applications of novel electrochemical sensors based on prussian blue

Design, optimization and applications of novel electrochemical sensors based on prussian blue

... logarithm of K+ concentration (inset of a) and logarithm of Na+ concentration (inset of b) S = electrode slope towards the logarithm of the relevant cation concentration Reproduced with permission from ... separation -based applications [30–32] As a continuation of the work on the Pt-coated nanoporous alumina membrane electrode, the direction of my honors year research project was on the exploration of ... a number of applications However, the pH stability of PB has been of concern, particularly under alkaline conditions [8] This constitutes a major drawback for PB -based applications, and much...
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The effects of capital structure on firm performance and firm transparency  a study of firms listed in ho chi minh stock exchange (hose)

The effects of capital structure on firm performance and firm transparency a study of firms listed in ho chi minh stock exchange (hose)

... EFFECTS OF CAPITAL STRUCTURE ON FIRM PERFORMANCE AND FIRM TRANSPARENCY: A STUDY OF VIETNAMESE ON- GOING FIRMS LISTED IN HO CHI MINH STOCK EXCHANGE (HOSE) In Partial Fulfillment of the Requirements ... financial transparency index and firm performance? Research Objectives Generally, this thesis is an empirical study of effects of capital structure on firm value of on- going firms (financial firms ... on- going firms capital listed in HOSE and the relationship between capital structure and firm performance - 11 - - To examine the relationship between firm s capital structure and firm s financial...
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ON THE DETERMINANTS OF CAPITAL STRUCTURE: AN EMPIRICAL STUDY OF VIETNAMESE LISTED FIRMS

ON THE DETERMINANTS OF CAPITAL STRUCTURE: AN EMPIRICAL STUDY OF VIETNAMESE LISTED FIRMS

... Journal of Law economics Franck B and Usha R.Mittoo (2002) The determinants of Capital structure choice: A survey of European firms Friend and Lang, An empirical test of the impact of managerial ... 1984, The capital structure puzzle, Journal of Finance Vol 39, p 575-592 Narayan Rao and Lukose P J., 2000, An Empirical Study on the Determinants of the Capital Structure of Listed Indian Firms ... where of the empirical context of the research Due to the limitation of the study, we could not intelligently discuss why Vietnam and Vietnamese firms as an empirical context yields the result of...
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ON THE DETERMINANTS OF CAPITAL STRUCTURE: AN EMPIRICAL STUDY OF VIETNAMESE LISTED FIRMS

ON THE DETERMINANTS OF CAPITAL STRUCTURE: AN EMPIRICAL STUDY OF VIETNAMESE LISTED FIRMS

... between woman on the board and performance 1.2 Objectives of the study An objective of the study is to examine in the Vietnamese bank, the link between women’s participation in top management and its ... responsibilities to the Company and its shareholders The Board plays the central role in the Company’s corporate governance and oversees the work of management and the execution of the Company’s ... the company's president and therefore also be one of the inside directors on the board (if not the chairman) * Chief Operations Officer (COO) – Responsible for the corporation's operations, the...
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A study of idioms containing terms for plants in english and vietnamese

A study of idioms containing terms for plants in english and vietnamese

... is easy to understand literal and transparent meaning 4.4 SIMILARITIES AND DIFFERENCES IN ENGLISH AND of an English and Vietnamese idiom containing TsFPs because its VIETNAMESE IDIOMS CONTAINING ... concerning idioms containing TsFPs with regard to syntactic and semantic features - Suggesting some implications for teaching and learning this popular kind of idioms in English and Vietnamese as a ... history allusion and cultural background containing TsFPs in particular as well as finding the translational 5.2.2 Implication for Teaching Idioms Containing TsFPs equivalents are not an easy task...
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Minimum Wages and Employment: A Case Study of the Fast-Food Industry in New Jersey and Pennsylvania pot

Minimum Wages and Employment: A Case Study of the Fast-Food Industry in New Jersey and Pennsylvania pot

... - Page of - You have printed the following article: Minimum Wages and Employment: A Case Study of the Fast-Food Industry in New Jersey and Pennsylvania David Card; Alan B Krueger The American ... findings for the fast-food industry by comparing changes in teenage employment rates in New Jersey, Pennsylvania, and New York in the year following the increase in the minimum wage Again, these ... 38-54 Card, David and Krueger, Alan B "Minimum Wages and Employment: A Case Study of the Fast Food Industry in New Jersey and Pennsylvania. " National Bureau of Economic Research (Cambridge, MA) Working...
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the effect of monetary incentive on effort and task performance a study of vietnamese company

the effect of monetary incentive on effort and task performance a study of vietnamese company

... provide a theoretical framework on the basic concepts and theories involved in monetary incentive in task and effort performance of managers and accountants There are not many things as monetary incentive ... companies use money to motivate managers and accountants on effort and task performance?  What happens if monetary incentives are not parallel with managers and accountants’ effort?  What are the ... So they are used as the basic for calculation of manager’s contractual pay-off They are also the basic to determine the reward and punishment for their’ performance The managers’ and accountants’...
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chemical reactor design, optimization, and scaleup

chemical reactor design, optimization, and scaleup

... z=u: The result is " u da ¼ RA dz ð1:36Þ u Reactor feed FIGURE 1.3 Piston flow reactor Reactor effluent 18 CHEMICAL REACTOR DESIGN, OPTIMIZATION, AND SCALEUP The initial condition is that a ¼ ain ... reaction of CHEMICAL REACTOR DESIGN, OPTIMIZATION, AND SCALEUP Equation (1.12) were reversible and elementary, its rate would be R ¼ kf ½AŠÀA ½BŠÀB Á Á Á À kr ½RŠR ½SŠS ð1:14Þ and it would ... b from Equation (1.11) 10 CHEMICAL REACTOR DESIGN, OPTIMIZATION, AND SCALEUP The only reactions that are strictly first order are radioactive decay reactions Among chemical reactions, thermal...
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Tiểu luận phương pháp nghiên cứu khoa học: Service personal values and customer loyalty A study of banking services in a transitio nal economy

Tiểu luận phương pháp nghiên cứu khoa học: Service personal values and customer loyalty A study of banking services in a transitio nal economy

...  Anana Nique, 2007; Schiffman Kanuk (1997); Kamakura Novak, 1992; Lages Fernandes , 2005; Liu et al., 2009: giá trị cá nhân NHÓM 12 – ĐÊM – KH A 22 Trang TIỂU LUẬN PHƯƠNG PHÁP NGHIÊN CỨU KHOA ... et al., 2007; Ples hco and Baqer, 2008; Shankar et al., 2003; Bigne´ et al., 2008; Han et al., 2008; Martin-Consuegra et al., 2007; Henning-Thurau et al., 2002; Wong and Zhou, 2006; Story and ... người tiêu dung  Parasuraman et al., 1988; Cronin and Taylor, 1992; Cronin et al., 1997; Lages and Fernandes, 2005; Cheng et al., 2008; Spreng and Singh, 1983; Oliver, 1980: th a mãn  Bowen Chen,...
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báo cáo sinh học:

báo cáo sinh học:" Employment and sociodemographic characteristics: a study of increasing precarity in the health districts of Belo Horizonte, Brazil" pdf

... and assistant health staff The values analysed refer to the basic annual salary for each year The changes in contractual salaries and related purchasing power were analysed by means of an income ... involved in the conceptualization, initial drafts and final write-up of the paper All authors had access to all data in the study and 18 19 Fritzen AS: Strategic management of the health workforce in ... The authors gratefully acknowledge the assistance of Dra Ana Flavia Machado, Professor of Demography at the University of Minas Gerais, in analysis of the data and for her helpful comments and...
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