The expression of CD44s in squamous cell carcinoma of the oral tongue and association with clinicopathological factors and survival outcomes

... glycosaminoglycan-associating proteins, increasing the capacity of these ligands to interact with their receptors, thereby lowing the threshold for signal transduction The binding of such ligands, including osteopontin ... is to investigate the expression of CD44s in squamous cell carcinoma (SCC) of the oral tongue using immunohistochemistry, and to correlate CD44s expression with histopathological features and patient ... Squamous Cell Carcinoma of the Oral Tongue 1.2.1 Epidemiology and Etiology Tongue cancer is the most common malignancy arising from the oral cavity in the head and neck As with most cancers in...

Báo cáo hóa học: " Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma''''" doc

... localized in the nucleus of tumor cells (A) High Oct4 expression in tumor cells, (B) low Oct4 expression in tumor cells, (C) high Sox2 expression in tumor cells, and (D) low Sox2 expression in tumor cells ... and Sox2 expression in hypopharyngeal squamous cell carcinoma Brown grains represent a positive signal (3, 3-diaminobenzidine staining) The positive expression site of Oct4 and Sox2 was mainly localized ... localized in the nucleus, were observed in the cancer cells of tumor tissues (Fig 1) The distribution of immunostaining Figure Expression of Oct4 and Sox2 Immunohistochemical staining for Oct4 and Sox2...

Báo cáo sinh học: "High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

... this article as: Chiu et al.: High ERCC1 expression predicts cisplatinbased chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area ... L: Chemotherapy added to locoregional treatment for head and neck squamous- cell carcinoma: three meta-analyses of updated individual data MACH-NC Collaborative Group Meta-Analysis of Chemotherapy ... expression of ERCC1 In addition, low Figure Analysis of ERCC1 expression in head and neck squamous cell carcinoma ERCC1 expression was determined using immunohistochemistry A) Low ERCC1 expression...

Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot

... protein expression and clinicopathological parameters /survival of HNSCC patients were also analyzed Materials and methods Page of 10 Virginia Cancer Registry Material was obtained with appropriate ... tumor -associated increase in expression of Her2 and Her3, using cut-offs of greater than or equal to +1 (range to +3)for membranous staining of Her2 and Her3, and greater than or equal to (range ... there was no association between cytoplasmic Her3 staining and any of the clinicopathological parameters examined (Table 2) When comparing primary tumor samples and matching metastatic samples,...

báo cáo hóa học:" High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

... this article as: Chiu et al.: High ERCC1 expression predicts cisplatinbased chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area ... L: Chemotherapy added to locoregional treatment for head and neck squamous- cell carcinoma: three meta-analyses of updated individual data MACH-NC Collaborative Group Meta-Analysis of Chemotherapy ... expression of ERCC1 In addition, low Figure Analysis of ERCC1 expression in head and neck squamous cell carcinoma ERCC1 expression was determined using immunohistochemistry A) Low ERCC1 expression...

báo cáo hóa học:" Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" doc

... protein expression and clinicopathological parameters /survival of HNSCC patients were also analyzed Materials and methods Page of 10 Virginia Cancer Registry Material was obtained with appropriate ... interpretation of both membranous and cytoplasmic staining Her2 (membranous) staining and Her3 membranous staining were scored according to the commonly applied criteria of Her2 membranous staining ... tumor -associated increase in expression of Her2 and Her3, using cut-offs of greater than or equal to +1 (range to +3)for membranous staining of Her2 and Her3, and greater than or equal to (range...

báo cáo hóa học:" Squamous cell carcinoma in situ arising in mature cystic teratoma of the ovary: a case report" ppt

... from a Mature Cystic Teratoma of the Ovary J Formos Med Assoc 2008, 107(11) Dos Santos L, Mok E, Iasonos A: Squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case series and ... data Lancet Oncol 2008, 9:1173-80 Dos Santos Lisa, Mok Evelyn, Alexia Iasonos, Kay Park, Soslow ARobert, Carol Aghajanian and co: Squamous cell carcinoma arising in mature cystic teratoma of the ... basal membrane is intact and the chorion is free Conclusion Squamous- cell carcinoma in situ arising in a mature cystic teratoma is an unusual disorder Because of the rarity of this disease, there...

Báo cáo khoa học: " Role of p53 mutation in the effect of boron neutron capture therapy on oral squamous cell carcinoma" ppsx

... oral SCC, its effect on the cell cycle and the cytotoxic effect on oral SCC cells irrespective of the p53 status should be clarified In the present study, we examined the effects of BNCT on the ... suppressed more strongly than SAS/mp53 cells At a dose of Gy, the Figure BNCT Suppression of the colony formation of oral SCC cells by Suppression of the colony formation of oral SCC cells by BNCT ... of 1 0boron to oral squamous cell carcinoma using boronophenylalanine and borocaptate sodium for boron neutron capture therapy Oral Oncol 2004, 40:474-482 Kamida A, Fujita Y, Kato I, Iwai S, Ono...

Báo cáo y học: "Squamous cell carcinoma of the nipple following radiation therapy for ductal carcinoma in situ: a case report" ppt

... from radiation therapy, which is about 6% at ten years [3] SCC of the nipple should be included in the differential diagnosis of a nipple lesion in a patient presenting after radiation therapy Other ... from the Childhood Cancer Sur- Figure p63 immunostaining of SCC Page of vivor study, radiation therapy was associated with a 6.3 fold-increase in risk for NMSC (SCC and basal cell carcinoma) Of these ... was obtained from the patient for publication of this case report and any accompanying images A copy of the written consent is available for review by the journal's Editor in Chief Abbreviations...

Báo cáo y học: "Peripheral primitive neuroectodermal tumor of the urinary bladder in an Arab woman with history of squamous cell carcinoma: a case report" doc

... 67-year-old diabetic and hypertensive Arab woman in February 2006, due to severe hematuria and fever In January 2005, the woman had already been treated in a hospital of Great Britain for repeated ... secondary tumor We report the first case of a peripheral primitive neuroectodermal tumor of the urinary bladder in an Arab country The Department of Surgery of Al Sabah Hospital, Kuwait admitted a ... and the dome of the urinary bladder (another site than described for the squamous cell carcinoma) As an initial attempt at transurethral resection (TUR) resulted in perforation, a partial bladder...

báo cáo khoa học: " Analysis of expression profiles of MAGE-A antigens in oral squamous cell carcinoma cell lines" ppsx

... the expression profiles of MAGE-A2 , MAGE-A3 , MAGE-A4 , MAGE-A6 and MAGE-A1 0 in oral squamous cell carcinoma cell lines by qrt-PCR and compared the results with the expression profile of a reference ... Figure ined RT-PCR-Blot of MAGE-A3 expression in the cell lines examRT-PCR-Blot of MAGE-A3 expression in the cell lines examined The intensity of the bands suggests different levels of expression ... http://www.head-face-med.com/content/5/1/10 Figure blot of MAGE-A4 expression in cell lines examined RT-PCR3 RT-PCR blot of MAGE-A4 expression in cell lines examined Cell line PCI 52 has a splice variant Besides this finding, there is...

Báo cáo y học: " Kaposi''''s sarcoma of the hand mimicking squamous cell carcinoma in a woman with no evidence of HIV infection: a case report" pptx

... presence of disease Figure regarded Kaposi's sarcoma carcinoma A primaryas a squamous cell on a hand, which was first A primary Kaposi's sarcoma on a hand, which was first regarded as a squamous cell ... treatment modality is still a matter of debate and no standard treatment guidelines are available Many patients have cutaneous lesions amendable to local therapy (cryotherapy, intralesional therapy, ... extremity KS may be mistaken in the skin for an inflammatory dermatosis, pyogenic granuloma, angiodermatitis or pseudo-Kaposi's, bacillary angiomatosis, angiosarcoma, bullous lesion in the rare cases...

Báo cáo y học: "Comparative study between the Hybrid Capture II test and PCR based assay for the detection of human papillomavirus DNA in oral submucous fibrosis and oral squamous cell carcinoma" pdf

... indentifying the association of HR-HPV types with these oral lesions The purpose of this study was to compare the efficacy of HC -II assay and PCR for the detection of specific HPV type (HPV 16 E6) in ... sensitivity has been developed known as hybrid capture II test (HC -II) and approved by the US food and drug administration (FDA) The performance characteristics of HC -II assay and the PCR for detection ... Concordance of results of HC -II assay and PCR test for detection of HPV infection in oral sub mucous fibrosis (OSMF): a potentially malignant oral lesionsa Table Concordance of results of HC -II assay and...

báo cáo khoa học:" Distant metastases of a squamous cell carcinoma of the tongue in peripheral skeletal muscles and adjacent soft tissues" doc

... funded in any way References In conclusion, we point out that distant metastases of SCC's of the head and neck region can manifest themselves in the peripheral skeletal muscles and adjacent soft ... oral and maxillofacial cancers: a report of cases J Oral Maxillofac Surg 2004, 62:1019-1024 Mess D, Songer M: Head and neck carcinoma metastases to the hand and foot A case report of simultaneous ... Nelson N: Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region A meta-analysis of prospective and randomized trials J Clin Oncol 1996,...

Báo cáo y học: "Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma" docx

... regulatory modules including TBPF (TATA -binding protein factors) , ECAT (enhancer of CCAAT binding factors) , or PCAT (promoter of CCAAT binding factors) p53 binding motifs were also displayed '(+)' and ... genotype and protein expression in UM-SCC cell lines p53 genotype and protein expression in UM-SCC cell lines (a) The p53 genotype of ten University of Michigan series head and neck squamous cell ... p53-NFYC (nuclear factor YC) and p53-YB-1 (Ybox -binding protein 1) were observed, and NFYC and YB-1 belong to ECAT and PCAT families It has been shown that YB-1 (also known as DNA binding protein...

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