... Effects of carbachol microinjection on CA1 pyramidal cell excitability 86 3.2.2 Spatial analysis of the effect of carbachol microinjection on CA1 pyramidal cell excitability 3.2.3 98 Relationship of ... field CA1 of the rat Brain Res 1004(1-2): 167-176 Jiang, F and Khanna, S (in preparation) Cholinergic mechanisms in supramammillary region mediate suppression...
... shown) Inhibition of pneumococcal murein hydrolases by bicyclic amines As shown above, tropic esters of bicyclic amines were selected and characterized by biophysical methods as strong ligands ... that the bicyclic amines are also able to bind to the active site of Pce Effect of choline analogs on cell growth and viability Fig Effect of choline and an...
... This report outlines the design of novel DNAzymes that target uPAR mRNA as a method of inhibiting its expression and thereby decreasing the invasive potential of tumor cells Results In vitro cleavage ... Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR-beta...
... activity of HL-60 Cells Utilizing the induced differentiation of HL-60 promyelocytic leukemia cells as a model of myeloid maturation, we examined the expression and location of Rac and PAK The interaction ... cells induced with ATRA Induction of Rac and PAK HL-60 cells were treated with lM ATRA for a week, and Rac and PAK were assayed in both cytoso...
... independently analyzed by two investigators The staining score was calculated from the staining intensity and percentage of positive staining cells The staining intensity was scored as (very weak), (weak), ... http://www.translational-medicine.com/content/9/1/64 Page of 10 Figure Analysis of the expression and localization of phosphorylated c-MET in RMS tissue samples Represen...
... independently analyzed by two investigators The staining score was calculated from the staining intensity and percentage of positive staining cells The staining intensity was scored as (very weak), (weak), ... http://www.translational-medicine.com/content/9/1/64 Page of 10 Figure Analysis of the expression and localization of phosphorylated c-MET in RMS tissue samples Represen...
... volunteers in Rio de Janeiro (Brazil) after oral vaccination with M bovis BCG Moreau RDJ Methods Volunteers and skin testing Healthy subjects aged 18–50 years were recruited who gave no history of pulmonary ... dose of oral vaccine and had been immunised in infancy via the oral and intradermal routes respectively, displayed an altered humoral immune response...
... 6E) From these results it can be concluded that tRNAs were bound in classical states with the tRNAMet bound f in the P-sites of the 30S and 50S subunits and the tRNAPhe bound in the A-site of the ... SF and tRNA were added simultaneously to the reaction mixtures, in agreement with the results presented by Wendrich et al [7] tRNA and ribosome-dependent syn...
... with an intra-peritoneal injection of 400 mg/kg chloral hydrate (Pharmaceutical Plant of Tiantan Hospital, Beijing, China) The rectal temperature was monitored and maintained at 37.5°C A scalp incision ... infarcted brain parenchyma of transplanted rats (A- iii and A- iv) A comparable extent of class II MHC was noted in ischemic rats irrespective of any therapy but unrema...
... that anti-RSV IgG incubation induced the removal and re-appearance of intracellular viral pro- Figure Confocal laser scanning image of intracellular RSV proteins Confocal laser scanning image of ... HEp-2 cells, anti-RSV IgG was added, and cell viability was determined at 2, 24, 48, and 72 h of incubation Sterile 0.2% ethylenediamine tetra acetate (EDTA) in 0.9% saline was added t...
... that anti-RSV IgG incubation induced the removal and re-appearance of intracellular viral pro- Figure Confocal laser scanning image of intracellular RSV proteins Confocal laser scanning image of ... HEp-2 cells, anti-RSV IgG was added, and cell viability was determined at 2, 24, 48, and 72 h of incubation Sterile 0.2% ethylenediamine tetra acetate (EDTA) in 0.9% saline was added t...
... altering cytokine production of a CD8+ T -cell subpopulation and by decreasing the antigenpresenting activity of dendritic cells Figure Effect of chitosan interferonc nanogene (CIN) therapy on the dendritic ... identified by intracellular cytokine staining and counted by flow cytometry after gating for tetramer-labelled cells C, Apoptosis of OVA-specific CD8+ T cell...
... Takeno M, Saito N, Yokoe T, Kaneko A, Asai T, Sakane T: Modulation by proinflammatory cytokines of Fas/ Fas ligand- mediated apoptotic cell death of synovial cells in patients with rheumatoid arthritis ... to FasL -induced cell death, and TNF -α prevented these cells from undergoing FasL -induced cell death in a dose-dependent manner No such inhibitory ef...
... against the allergic airway inflammation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice Genetic Vaccines and Therapy 2010, 8:2 Page of ... and mature DCs, resulting in tolerogenic interaction with T cells in SIT We found that the combination of DNA vaccination with Fc and OVA...
... The number of amino acids comprising the extra- and intracellular loops and the extracellular N-terminal and intracellular C-terminal regions of the bovine A1 receptor are indicated in parentheses ... during the adenosine- induced apoptosis in 163 BHK cells Fig 3.70 Activation of caspase during the adenosine- induced apoptosis 165 in BHK cells Fig 3.71 Caspase-...