Genomic and transcriptomic analysis of gastric cancer systematic studies on transcriptional bias in aneuploidy and gene coexpression meta network
Genomic and transcriptomic analysis of gastric cancer systematic studies on transcriptional bias in aneuploidy and gene coexpression meta network
... Table 2.3 Gene expression levels of ERBB2 and surrounding genes in gastric cancer cell lines .66 Table 2.4 Gene expression levels of oncogenes and proto-oncogenes in gastric cancer ... expression profiling platforms The gene- gene coexpression interactions from different expression datasets of gastric cancer are systematically coalesced into vii a single unified coexpression interaction ... profiles of cancers First, the existence of transcriptional bias in the regions of aneuploidy is addressed by showing pervasive imprinting of aneuploidy on the cancer transcriptome by reconstructing...
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báo cáo hóa học:" Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancer" pptx
... Normal High- risk Group Group B EGC Group AGC Group Metastasis Group Ser um HMGB1 level (ng/ml ) * † 1 Normal Group High- risk Group EGC Group AGC Group Metastasis Group Figure Serum levels of CEA and ... gastritis and ulcer (normal group) , 50 with IM including adenoma (high risk group) , 40 with EGC (EGC group) , 45 with AGC without distant metastasis (AGC group) , and 42 with metastatic GC (M group) The ... specificity of HMGB1 compared to CEA for the diagnosis of high- risk lesions and EGC The CEA and HMGB1 cut-off points that gave the best sensitivity and specificity for the diagnosis of high- risk lesions...
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Báo cáo hóa học: " Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance" pptx
... on Cancer 2009, 1796:11-18 doi:10.1186/1479-5876-8-101 Cite this article as: Peng et al.: Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory ... interface of tumor nest and stroma is the main location of infiltrating macrophages in gastric cancer, and phagocytosis of cancer cells by macrophage, indicating the coexistence of M1 and M2 phenotypes ... focus on cancer itself A major drawback of such study, however, is the lack of appreciation of the “temporal and spatial coevolution of cancer and its environment”, which is the real context of tumor...
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Báo cáo sinh học: "Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer" pdf
... Shomura H, Homma S, Maeda Y, Tokunaga N, Ikeda Y, Ishihara Y, Yamada A, Tanaka N, Itoh K, Harada M, Todo S: Immunological evaluation of personalized peptide vaccination in combination with a 5-fluorouracil ... cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer Journal of Translational Medicine 2011 9:140 Submit your next manuscript to BioMed Central and take full advantage ... vaccination with mGC8 cells and GM-CSF T cells generated from TVDLN at day nine after vaccination were polyclonally activated and expanded as described in the Methods section and tested for tumorspecific...
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báo cáo hóa học:" Gene Expression and Pathway Analysis of Ovarian Cancer Cells Selected for Resistance to Cisplatin, Paclitaxel, or Doxorubicin" docx
... selected for resistance to cisplatin, doxorubicin or paclitaxel, and we use gene expression profiling to identify genes and pathways that may be important to the development of drug resistance in ovarian ... Gene expression and pathway analysis of ovarian cancer cells selected for resistance to cisplatin, paclitaxel, or doxorubicin Cheryl A Sherman-Baust1, Kevin ... (OV90P) Pathway analysis of drug resistance In order to gain some insight into the possible mechanisms important in the development of resistance to these drugs, we performed pathway analysis...
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Báo cáo khoa học: "Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro" ppsx
... lines In addition, propranolol showed a synergism of growth inhibition in combination with irradiation in SGC-7901 and BGC-823 cells On the contrary, isoproterenol demonstrates anti-irradiation ... Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro Radiation Oncology 2010 5:98 Submit your next manuscript to BioMed Central and take ... SGC-7901 cells There was an increasing rate of apoptosis in gastric cancer cell lines in response to the following treatments: isoproterenol before irradiation, irradiation only, and propranolol...
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báo cáo khoa học: " The function and mechanism of COX-2 in angiogenesis of gastric cancer cells" pdf
... types of human cancer However, the mechanism of COX-2 in angiogenesis remains unclear In this study, the data showed that down-regulation of COX-2 could significantly inhibit the in vitro and in ... et al.: The function and mechanism of COX-2 in angiogenesis of gastric cancer cells Journal of Experimental & Clinical Cancer Research 2011 30:13 Acknowledgement This study was supported in part ... proliferation of SGC7901 cells (Figure 2A) As shown in Figure 2B, down-regulation of COX-2 might inhibit the malignant growth of SGC7901 cells in vivo Down-regulation of COX-2 inhibited angiogenesis of gastric...
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báo cáo khoa học: " Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells" docx
... 1D), suggesting that down-regulation of miR-27a might inhibit the growth of MKN45 cells in vitro and in vivo Down-regulation of miR-27a might reverse drug resistance of gastric cancer cells As shown ... down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells through regulation of P-gp, cyclin D1 and p21 MiR-27a might be considered as a valuable target for cancer ... al.: Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells Journal of Experimental & Clinical Cancer Research 2011 30:55 Conclusions In conclusion, down-regulation...
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báo cáo khoa học: "Recombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells" docx
... target for this type of cancer [3] The aim of this study was to evaluate the effects of recombinant immunotoxin anti-c-Met/PE38KDEL on proliferation and apoptosis of GC cells and explore the mechanism ... as: Wei et al.: Recombinant immunotoxin anti-c-Met/ PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells Journal of Experimental & Clinical Cancer Research 2011 30:67 ... Yamamoto H: Participation of c-met in the progression of human gastric cancers: anti-c-met oligonucleotides inhibit proliferation or invasiveness of gastric cancer cells Cancer Gene Ther 1996, 3:393-404...
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báo cáo khoa học: " Transcriptomic analysis of pluripotent stem cells: insights into health and disease" potx
... 2011 doi:10.1186/gm284 Cite this article as: Yeo J-C, Ng H-H: Transcriptomic analysis of pluripotent stem cells: insights into health and disease Genome Medicine 2011, 3:68 ... developmental defects and mental retardation due to dysregulation of gene expression [29] ESC, embryonic stem cell; hiPSC, human induced pluripotent stem cell; iPSC, induced pluripotent stem cell; miRNA, ... application of induced pluripotent stem cell technology for therapeutic purposes Patient-derived somatic cells can be isolated through tissue biopsies and converted into induced pluripotent stem cells...
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báo cáo khoa học: " Transcriptomic analysis of tomato carpel development reveals alterations in ethylene and gibberellin synthesis during pat3/pat4 parthenocarpic fruit set" pps
... Clustering of genes that changed during normal carpel development and fruit set (TIME) Clustering of genes that changed during normal carpel development and fruit set (TIME) Cluster analysis of genes ... relevant and asses the importance of GAs for parthenocarpic development and a new role for ethylene in this process Results Transcriptomic analysis of tomato carpel development and fruit set Carpel development ... expression of subsets of the IAA and ACS genes and the alterations in fruit morphology suggest that early stages of fruit development in tomato are regulated by auxin and ethylene [47] In pat3/pat4...
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Báo cáo y học: "A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database" ppt
... residues, the other of tyrosines This grouping is based on the similar characteristics of serine and threonine, and the fact that they are usually targeted by the same protein kinases The study focused ... identity cut-off (>30%) very few sites were highly conserved (Figure 7a) Only less than 5% of the sites were strictly conserved across the alignments, and not more than 20% of the sites were conserved ... motif on the surface of the protein (Figure 10g) Its phosphorylation may affect the conformation of this motif, which is involved in RNA -protein interactions [70] Finally, the structure of the...
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Molecular signatures of gastric cancer an integrated approach to molecular cytogenetics, whole genome copy number and transcriptome profiles
... epidemiology and clinical features Gastric cancer etiology 21 The African and Asian enigma 50 Possible molecular pathogenetic attributes of gastric cancer 66 Translocations in epithelial tumors and their ... balanced translocation in IM95 10 Dissecting complex rearrangements: integrating spectral 235 karyotypes and whole genome copy number profiles 10.1 Global integration of SKY and copy number analysis ... It ranks fourth as a cause of cancer mortality, having an ASR of 10.5 in males and 5.6 in females, respectively15 Figure 1-5 Age-standardized cancer incidence and mortality rates of common cancers...
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An analysis of errors made by vietnamese secondary school students in using english modal auxiliary verbs can, could, may, must and semi auxiliary verb have to
... thorough analysis of the errors committed by Vietnamese students of English in using English modal verbs can, could, may, have to and must An analysis specializing in errors in using English modal verb ... the errors in using modal verbs can, could, may, , must and semi -auxiliary verb have to by Vietnamese learners at TL secondary school - Find the major causes and sources of their errors and - ... teaching and learning: can, could, may, have to, and must 1.3 SCOPE OF THE STUDY Within the limitation of a graduation thesis, I would like to deal with modal verbs can, could, may, have to and must...
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