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The roles of a global ph sensor protein chvg in homologous recombination and mutation of agrobacterium tumefaciens

The roles of a global ph sensor protein chvg in homologous recombination and mutation of agrobacterium tumefaciens

The roles of a global ph sensor protein chvg in homologous recombination and mutation of agrobacterium tumefaciens

... Adenine is deaminated to hypoxanthine in DNA at only 2-3% of the rate of cytosine deamination and the deamination of guanine to xanthine is even smaller than that for adenine (Karran and Lindahl, 1980) ... tetracycline and 143 x norfloxacin Fig 4.13 Starvation mutation assay 149 Fig 4.14 Mutation pattern at stationary phase 152 Fig 4.15 Growth curve of the chvG+ strain A6 007 and the chvG strain A6 340 ... description in 1991 (Cairns and Foster, 1991), FC40 has become the most popular strain in the study of adaptive mutation The reason is clear: the abundance of adaptive lac+ mutations that appear makes the...
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Báo cáo khoa học: Flexible nets The roles of intrinsic disorder in protein interaction networks potx

Báo cáo khoa học: Flexible nets The roles of intrinsic disorder in protein interaction networks potx

... number of protein protein interactions ⁄ number of complexes (inter ⁄ comp.), while the STRING search results are presented as number of protein protein interactions (inter.) only Proteins are ... contained regions of intrinsic disorder One example of an ordered hub, calmodulin, makes use of a flexible hinge to facilitate binding diversity Each of these classes and their roles in protein protein ... important roles in the binding interactions of these hub proteins The xeroderma pigmentosum group A protein (XPA) represents an interesting example of a partially disordered hub protein Xeroderma...
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INVESTIGATING THE HOST IMMUNE RESPONSE TO MYCOBACTERIUM TUBERCULOSIS THE ROLES OF ANNEXIN a1 PROTEIN AND CLEC9A+ DENDRITIC CELLS

INVESTIGATING THE HOST IMMUNE RESPONSE TO MYCOBACTERIUM TUBERCULOSIS THE ROLES OF ANNEXIN a1 PROTEIN AND CLEC9A+ DENDRITIC CELLS

... INVESTIGATING THE HOST IMMUNE RESPONSE TO MYCOBACTERIUM TUBERCULOSIS: THE ROLES OF ANNEXIN A1 PROTEIN AND CLEC9A+ DENDRITIC CELLS KOH HUI QI VANESSA (B Sc (Life Sciences, Hons.), NUS) A THESIS ... variety of immune cells, and the role of CLEC9A+ dendritic cells (DCs), which includes CD103+ migratory DCs in the lung and CD8+ DCs in the lymphoid organs First, using an ANXA1−/− mouse model of ... The heterogeneous consequences of M tuberculosis infection The implications of the heterogeneity of the host immune response to M tuberculosis infection are becoming increasingly recognised The...
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The roles of rac1 and syncollin in regulated exocytosis  insulin secreting INS 1 cells as a model

The roles of rac1 and syncollin in regulated exocytosis insulin secreting INS 1 cells as a model

... study, the possible roles of two proteins (Rac1 and syncollin) in regulated exocytosis were investigated by using insulin- secreting INS- 1 cells as a model system Rac1 is a member of the Rho family ... in evolution Insulin is initially synthesized as preproinsulin, the precursor of insulin, which has a 24 amino acid signal peptide in the N terminal and a 31 amino acids connecting peptide (C-peptide) ... Plasmid Description pIRES Deleting the inserts from pIRES-N1 7Rac1 pIRES-N1 7Rac1 5’ flank c-myc tagged N1 7Rac1 pIRES-V1 2Rac1 5’ flank c-myc tagged V1 2Rac1 pIRES -Rac1 5’ flank c-my tagged Rac1...
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Tài liệu Báo cáo khoa học: Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Structure of the reduced enzyme-progesterone complex and the roles of residues Tyr186, His181 and His184 pdf

Tài liệu Báo cáo khoa học: Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Structure of the reduced enzyme-progesterone complex and the roles of residues Tyr186, His181 and His184 pdf

... histidine residues in PETN reductase inferred to be involved in ligand binding and counterpart residues in related enzymes and also the location of the tyrosine residue implicated as proton donor in ... unusual in having two histidine residues (rather than the His-Asn pair seen in OYE, MR and some of the other member proteins; Fig 1B) in the active site for ligand and substrate binding For those ... 1A) and 2-cyclohexen-1-one indicate that these ligands bind above the si face of the FMN isoalloxazine ring and are held in position by hydrogen bond interactions with His181 and His184 [2] These...
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Báo cáo khoa học: Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis pptx

Báo cáo khoa học: Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis pptx

... representation of the roles of the FadD proteins encoded by the DIM + PGL locus in the biosynthesis of DIMs and related compounds in Mycobacterium tuberculosis The role of the activation enzymes FadD22, FadD26 ... protein involved in the biosynthesis of PGL-tb in M tuberculosis These data also established that, in contrast to fadD26, fadD29 does not play any role in the biosynthesis of DIMs in M tuberculosis ... redundancy of these proteins in the activation of the various intermediates in DIM and PGL biosynthesis has not been analyzed This study was undertaken to dissect the roles of FadD22, FadD26 and FadD29...
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The Economics of Small Business Finance: The Roles of Private Equity and Debt Markets in the Financial Growth Cycle potx

The Economics of Small Business Finance: The Roles of Private Equity and Debt Markets in the Financial Growth Cycle potx

... cycle of small business. 4 The Financial Growth Cycle of Small Business Small business may be thought of as having a financial growth cycle in which financial needs and options change as the business ... funds in the private equity and debt markets The flow and pricing of private equity depend crucially on the public equity markets The pricing of angel finance and venture capital at the origination ... provide the bulk of the fund’s returns IV The Role of Private Debt Markets in Small Business Finance We next turn to the private debt markets that finance small business As discussed above, the capital...
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Báo cáo khoa học: Identification and expression of the first nonmammalian amyloid-b precursor-like protein APLP2 in the amphibian Xenopus laevis ppt

Báo cáo khoa học: Identification and expression of the first nonmammalian amyloid-b precursor-like protein APLP2 in the amphibian Xenopus laevis ppt

... lack of a second heparin-binding domain [3,4,13,26] Comparative analysis of the Xenopus and mammalian APLP2 proteins Comparing the amino acid sequences of the two X -APLP2 proteins with the human, ... domains within a protein, we here identify the first nonmammalian APLP2 protein in the amphibian Xenopus laevis and present a phylogenetic analysis of the APP superfamily that now therefore includes ... exclusively in the brain and further displays a number of structural features not present in the other members of the APP superfamily, such as the absence of the exon encoding the KPI domain and the...
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Báo cáo khoa học: cGMP and glutathione-conjugate transport in human erythrocytes The roles of the multidrug resistance-associated proteins, MRP1, MRP4 and MRP5 pot

Báo cáo khoa học: cGMP and glutathione-conjugate transport in human erythrocytes The roles of the multidrug resistance-associated proteins, MRP1, MRP4 and MRP5 pot

... and that vincristine inhibits the high affinity DNP-SG transport in the presence but not in the absence of GSH [12,45,46] Thus the effect of vincristine on the cGMP uptake was also tested in the ... these and cGMP block low affinity [3H]DNPSG transport in human erythrocytes and so the low affinity transport of DNP-SG and the transport of cGMP may be mediated by one and the same transporter The ... phosphodiesterase inhibitor, inhibited transport All of these effects are compatible with cGMP transport by a member of the MRP family Immunodetection of MRP4 and MRP5 proteins in human erythrocytes and COR-L23/R...
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The Roles of the Aesthetic in Mathematical Inquiry doc

The Roles of the Aesthetic in Mathematical Inquiry doc

... groups of aesthetic responses, which play three distinct roles in mathematical inquiry The most recognized and public of the three roles of the aesthetic is the evaluative; it concerns the aesthetic ... about their results AESTHETIC IN MATHEMATICAL INQUIRY 265 dimensions of mathematics As such, in illustrating each role of the aesthetic in mathematical inquiry, I also attempt to identify the ... values—some of the elements of the affective domain (Goldin, 2000)—that are intertwined with aesthetic responses The three roles of the aesthetic in mathematical inquiry that I have identified have their...
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The roles of the various plasma agents in the inactivation of bacteria

The roles of the various plasma agents in the inactivation of bacteria

... tube, along the nozzle, and in the surrounding air The length of the plasma plume can reach as long as cm with helium as working gas To investigate the role of the charged particles in the inactivation ... range, are playing the main role in the inactivation process Finally, the measurements of the UV intensity show that the UV emission is too weak to play a crucial direct role in the inactivation ... contribution of the charged particles to the inactivation of bacteria The plasma plume carries a peak current of about 300 mA as reported in Ref In the mean time, the electric field along the plasma...
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Business Change - The Roles of Change Agents and Subject Matter Experts in Organization Change potx

Business Change - The Roles of Change Agents and Subject Matter Experts in Organization Change potx

... or other affiliation with this book Business Change - The Roles of Change Agents and Subject Matter Experts in Organization Change And Much More… - 101 World Class Expert Facts, Hints, Tips and ... 29 Business Change - The Roles of Change Agents and Subject Matter Experts in Organization Change 30 Successful Change Management Tips .31 Continuously Improve Your Business Using ... expediters, and "dead -in -the- water" inventory The only way to avoid this problem in the plant is by investing effort upstream and, in designing the off-line activities more carefully The same upstream and...
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Báo cáo y học:

Báo cáo y học: "κ The roles of the classical and alternative nuclear factor-κB pathways: potential implications for autoimmunity and rheumatoid arthritis" ppsx

... plays an important role in the regulation of immune central and peripheral tolerance, and hence in autoimmune reactivity of the immune system Autoimmunity Autoimmunity is the result of a loss of ... characteristic of self-autoreactivity [51-54] However, loss of any one of the receptors and/ or their ligands results in relatively mild defects compared with loss of the alternative pathway, most likely because ... released into the periphery and migrate to those sites, further proinflammatory effects of NF-κB come into play that aggravate and perpetuate the disease We recently reviewed the roles played by NF-κB...
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Báo cáo y học:

Báo cáo y học: "Understanding the roles of the transcription factors nuclear κ α factor-κB and hypoxia-inducible factor-1α in lung injury" pptx

... translocation and increases IκB expression in κ α A549 cells J Clin Invest, 99:2423-2428 Lentsch AB, Shanley TP, Sarma V, Ward PA: In vitro suppresκ κ α sion of NF-κB and preservation of IκB by interleukin-13 ... consists of two subunits HIF- 1α, a DNAbinding protein, has increased stability and binding in hypoxic conditions and is degraded rapidly in normoxia The accumulation of the α- subunits allows for α ... review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated α lung injury: role for hypoxia-inducible factor- Crit Care 2003, 7 :in press Fein AM, Calalang-Colucci...
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