... Fluorescence studies of RepA R E M Diederix et al Interestingly, in the latter case, the protein binds as a monomer [26] Free in solution, the protein is essentially dimeric, ... DNA-binding domains, and rearrangement of the relative orientation of the two domains [7,9] The conformational change upon iteron binding may expose a recognition site for proteinprotein interaction, ... latter protein, the crystal structures of both the monomeriteron and dimeroperator complexes are available, indicating secondary structural changes in the linker connecting the dimerization and...