The investigation of transcription related protein protein interactions of histones in saccharomyces cerevisiae
The investigation of transcription related protein protein interactions of histones in saccharomyces cerevisiae
... THE INVESTIGATION OF TRANSCRIPTION- RELATED PROTEIN- PROTEIN INTERACTIONS OF HISTONES IN SACCHAROMYCES CEREVISIAE ZHAO JIN (M Sc (Molecular Engineering of Biological and Chemical ... Aim of the study To investigate the effects of single point mutation of histones on transcription regulation and the relevant protein- protein interactions in Saccharomyces cerevisiae To study the ... number of interactions detected in larger screens Meanwhile as the design of the split-ubiquitin system poses steric constraints on the two fusion proteins, almost all protein- protein interactions...
- 134
- 382
- 0
Báo cáo khoa học: The role of histones in chromatin remodelling during mammalian spermiogenesis pot
... divergence in chromatin remodelling One of the most distinctive characteristics of chromatin remodelling during spermatogenesis is the expression of a large number of histone variants Indeed, in addition ... bromodomain-bearing proteins, enabling them to bind acetylated chromatin (Fig 3) Bromodomains are acetyl-lysine binding modules present in ATP-dependent chromatin remodelling factors as well as in ... H3.3 is incorporated during the first meiotic prophase, then concentrated in a limited number of chromatin regions and further disappears with the other core histones during the elongation of spermatids...
- 11
- 616
- 0
Aerobic Uptake of Cholesterol by Ergosterol Auxotrophic Strains in Candidaglabrata & Random and Site-Directed Mutagenesis of ERG25 in Saccharomyces cerevisiae
... 2010 Aerobic Uptake of Cholesterol by Ergosterol Auxotrophic Strains in Candida glabrata & Random and SiteDirected Mutagenesis of ERG25 in Saccharomyces cerevisiae Major Professor: Dr Martin Bard ... Research Integrity and Copyright Disclaimer Title of Thesis/Dissertation: Aerobic Uptake of Cholesterol by Ergosterol Auxotrophic Strains in Candida glabrata & Random and Site-Directed Mutagenesis of ... UPTAKE OF CHOLESTEROL BY ERGOSTEROL AUXOTROPHIC STRAINS IN CANDIDA GLABRATA & RANDOM AND SITE-DIRECTED MUTAGENESIS OF ERG25 IN SACCHAROMYCES CEREVISIAE A Thesis Submitted to the Faculty of Purdue...
- 101
- 140
- 0
Báo cáo khoa học: Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein potx
... by DSC to be the Tm of the protein These fibrils are amyloidogenic, as determined from their Stability and fibril formation of TTR and TRP tinctorial properties in the ThT-binding and CR-binding ... with the thermostability of its tetrameric and monomeric structures Thermostability and protein structures We have analyzed the structures of hTTR (Protein Data Bank code: 1F41 [12]), sbTTR (Protein ... cold-adapted proteins and distinguishes them from their mesophilic and thermophilic counterparts is their lower thermal stability [66] This could therefore be one explanation for the reduced stability...
- 13
- 419
- 0
báo cáo khoa học: " The YlmG protein has a conserved function related to the distribution of nucleoids in chloroplasts and cyanobacteria" pdf
... 5'-TCAAGTCTTCCAATTTCTACCCAGTGCTGC-3' for AtYLMG1-1, 5'CCTCAACATATATAACACCATC-3' and 5'-GACAGGTTCAGGTCATAGAAG-3' for At5g21920, 5'-TATCTGAACACTCCGTTGACGGTA-3' and 5'-CAAAGATA AACGGAATACGATC-3' for At4g27990, ... identify the inserted 35S-cDNA in the FOX lines, the insertion was amplified by PCR using primers 5'GTACGTATTTTTACAACAATTACCAACAAC-3' and 5'-GGATTCAATCTTAAGAAACTTTATTGCCAA-3', and then sequenced by a ... resistance to kanamycin, was amplified by primers 5'-ATGTCTAGAAGCTATGACCATGATTACGAA-3' and 5'-ATGTC TAGAAAGTCAGCGTAATGCTCTGCC-3' (the XbaI site is underlined), digested with XbaI, and inserted into...
- 13
- 453
- 0
Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
... Bhagwat SV, Biswas G, Anandatheerthavarada HK, Addya S, Pandak W & Avadhani NG (199 9) Dual targeting property of the N-terminal signal sequence of P450 1A1 Targeting of heterologous proteins to ... open N-terminal signal domain is critical for protein targeting to the ER (Fig 2D) In contrast to the targeting of CYP 1A1 requiring N-terminal truncation, we have shown that intact CYP2B1 and CYP2E1 ... that xenobiotic-inducible CYPs such as rat CYP 1A1 , CYP2E1 and CYP2B1, and mouse CYP 1A1 , contain chimeric noncanonical -targeting signals that are capable of targeting proteins to both the ER and...
- 16
- 650
- 0
Báo cáo khoa học: The role of Tyr71 in Streptomyces trypsin on the recognition mechanism of structural protein substrates ppt
... using surface plasmon resonance analysis to determine the role of residue 71 in collagen binding The elucidation of the mechanism of structural protein substrate recognition in serine proteases should ... compilation ª 2009 FEBS 5643 Substrate recognition mechanism of Streptomyces trypsin into the NdeI–HindIII gap of pTONA5a to construct the expression vector To prepare the mutant SOT-Y71L, the mutagenic ... placed in the same direction, and a cassette containing the Gmr and E coli rpsL+ genes was inserted between them rpsL+ encodes the ribosomal protein S12 [23], the target of Sm The transformation of...
- 13
- 469
- 0
Báo cáo khoa học: Differential tissue-specific distribution of transcripts for the duplicated fatty acid-binding protein 10 (fabp10) genes in embryos, larvae and adult zebrafish (Danio rerio) docx
... show differential tissue-specific distribution of fabp10a and fabp10b transcripts in developing and adult zebrafish, evidence of the divergence of regulatory elements in the promoters of the fabp10a ... vesicles indicates a potential role for this protein in the early development of the zebrafish brain Tissue-specific distribution of fabp10b gene transcripts in adult zebrafish The tissue-specific distribution ... transcripts in embryos, larvae and adult zebrafish show strikingly different tissue-specific patterns of distribution On the basis of the distribution of fabp10b transcripts in many tissues of adult zebrafish, ...
- 11
- 402
- 0
Báo cáo khoa học: Calcium-dependent protein–protein interactions induce changes in proximity relationships of Cys48 and Cys64 in chicken skeletal troponin I ppt
... Grabarek, Z & Drabikowski, W (1978) Proteolytic fragments of troponin C: Localization of high and low affinity Ca2+ binding sites and interactions with troponin I and troponin T J Biol Chem 253, 5452–5459 ... 5230–5240 37 Tripet, B., Van Eyk, J.E & Hodges, R.S (1997) Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the ... importance of each amino acid residue of the troponin I inhibitory sequence 104–115 in the interaction with troponin C and tropomyosinactin J Biol Chem 263, 1726–1732 19 Wilkinson, J.M & Grand, R.J.A (1978)...
- 9
- 339
- 0
Báo cáo khoa học: " The role of mutations in core protein of hepatitis B virus in liver fibrosis" pdf
... HBV has To explain the < /b> effect of < /b> mutations < /b> of < /b> core < /b> protein < /b> in < /b> the < /b> biological process of < /b> the < /b> cell, we predicted the < /b> major functions of < /b> the < /b> core < /b> protein < /b> of < /b> hepatitis < /b> B virus Protein < /b> prediction function ... clinical findings of < /b> chronic hepatitis < /b> B patients in < /b> correlation with mutations < /b> in < /b> Immunodominant epitopes and C-terminal domain of < /b> HBV core < /b> protein < /b> The < /b> mean of < /b> HAI score and fibrosis stage in < /b> subjects ... in < /b> such Table 3: The < /b> correlation of < /b> mutations < /b> in < /b> Immunodominant epitopes and C-terminal domain of < /b> HBV core < /b> protein < /b> with clinical finding of < /b> 29 chronic hepatitis < /b> B patients Immunodominant epitopes...
- 9
- 288
- 0
Báo cáo y học: " The role of IFN-γ in regulation of IFN-γ-inducible protein 10 (IP-10) expression in lung epithelial cell and peripheral blood mononuclear cell co-cultures" potx
... source of IFN-γ in the adaptive immune response [2,3] IFN-γ- inducible protein 10 (IP -10) is induced by IFN-γ in many types of cells including monocytes and lung epithelial cells [4,5] IP -10, also ... haematology analyzer to determine total cell number and the purity of the cell preparation This method typically yields a cell suspension containing 80– 95% of lymphocytes and 5–20% monocytes The cells ... complex interaction between lung epithelial cells and white blood cells, we decided to investigate the role of the IFN-γ/ IL-12 pathway on IP -10 secretion upon the interaction of peripheral blood mononuclear...
- 11
- 351
- 0
Functional role of low density lipoprotein receptor related protein 5 and 6 in alzheimers disease
... through binding to low- density lipoprotein receptor- related protein 5/ 6 in SH-SY5Y cells Manuscript in preparation Zhang L, Bahety P, Ee PL Protective role of Wnt signaling co-receptors LRP5 /6 against ... APOLIPOPROTEIN E4 DISRUPTS NORMAL MITOCHONDRIAL DYNAMICS THROUGH BINDING TO LOWDENSITY LIPOPROTEIN RECEPTOR- RELATED PROTEIN 5/ 6 IN SHSY5Y CELLS 75 5.1 Introduction 75 5.2 ... 55 CHAPTER CHARACTERIZATION OF THE INTERACTION BETWEEN LRP5 /6 AND APOLIPOPROTEIN E PROTEINS 56 4.1 Introduction 56 4.2 Materials and Methods 57 4.2.1 Cell culture and...
- 157
- 264
- 0
Mutational analysis of the TATA binding protein (TBP) in saccharomyces cerevisiae
... ubiquitin attached to Protein X and the Cterminus to Protein Y and the reporter RUra3p 47 Figure 2.8 Interaction between Protein X and Protein Y Interaction of the two proteins brings about the ... able to interact with TFIIF more rapidly, resulting in strong activation of transcription (Choi et al., 2003) 2.5.1.3 TFIID /TATA- Binding Protein The TATA- binding protein, Tbp1p, binds to the TATA- box ... transcription by initiating the recruitment of limiting factors at the promoter The raising of the local concentrations of these limiting factors at the promoter brings about the recruitment of other transcription...
- 212
- 238
- 0
Functions of the dynamin like protein VPS1 in actin organization in saccharomyces cerevisiae
... FUNCTIONS OF THE DYNAMIN- LIKE PROTEIN VPS1 IN ACTIN ORGANIZATION IN SACCHAROMYCES CEREVISIAE YU XIANWEN (B.Sc., XIAMEN UNIVERSITY) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY INSTITUTE ... PRD, proline arginine rich domain (B) The domain structure of dynamin- like proteins 1.3.1.1 Domains and properties of dynamins Dynamins are different from the small GTPases in that they are large, ... tyrosine kinases The binding between dynamins and these signaling proteins can be stimulated upon growth factor treatments, indicating the involvement of dynamin in cellular signaling pathway The...
- 225
- 253
- 0
Từ khóa: validity of sleep nasendoscopy in the investigation of sleep related breathing disordergene s sequence and the level of activity in the associated protein are as variable as any other human traitet al 1996 insertion of the 70 kda peroxisomal membrane protein into peroxisomal membranes in vivo and in vitro j biol chem 271 7 3706 13the role of flavonoids in fruits and vegetables related to breast cancer preventionthe investigation of gene regulation and variation in human cancers and other diseasesvisualizing protein interactions with chromatin in vivtechniques for the investigation of electrode reaction kineticsenergetics kinetics and the investigation of mechanismwhat is the diagnostic performance of computed tomography in the investigation of ankle fractures in childrenwhat is the diagnostic performance of magnetic resonance imaging in the investigation of ankle injuries in childrenwhat is the diagnostic performance of ultrasound in the investigation of ankle injuries in childrenbps and structurally related substances in the effects of bps in micethe investigation of anaemia and the anaemia of chronic diseasesome analytic tools used in the investigation of solvability of boundary value problems for a b elliptic equationsdose response assessment — quantitative methods for the investigation of dose response relationshipsBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ