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Genetic determinants of infectious disease susceptibility 2

Genetic determinants of infectious disease susceptibility 2

Genetic determinants of infectious disease susceptibility 2

... 42/ 235/ 321 61 /24 6 /29 3 1/44/490 13/93/433 7/ 126 /407 43 /22 9 /26 2 78 /24 2 /22 0 2/ 73/464 35 /20 6 /29 9 35 /20 6 /29 9 45 /21 6 /27 8 8/60/467 35 /22 2 /28 3 118 /27 7/1 42 13/94/4 32 14/133/393 35 /20 7 /29 8 66 /25 5 /21 6 14/133/393 ... 11/ 124 /464 29 /198/3 72 3/71/ 526 25 /171/404 1/71/ 527 31/198/369 2/ 64/533 3/46/550 1 32/ 284/183 24 /175/400 101/304/194 61 /23 5/301 17/146/436 92/ 305 /20 3 32/ 203/364 29 /20 9/359 134 /27 1/194 42/ 235/ 321 ... 14/133/393 25 /168/347 69 /24 3 /22 7 0 /26 /514 45 /22 2 /27 3 8/111/416 22 /173/336 5/109/ 421 1/8/531 3/101/430 8/130/4 02 18/174/347 5/ 72/ 455 18/1 42/ 375 1/77/4 62 35/181/ 324 1/48/491 0/37/503 101 /27 1/167 27 /166/347...
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Genetic determinants of infectious disease susceptibility

Genetic determinants of infectious disease susceptibility

... us to use genetic mapping for discovering relevant genes in pulmonary TB susceptibility For this kind of common disease, the genetic mode of action frequently attributed from multiple genetic factors, ... environment, cause infectious diseases The intrusive attack of such infectious agents typically triggers a natural cascade of tightly regulated immune responses to control the infection, which often resulted ... polygenic spectrum of common complex trait Therefore, it is not surprising that most success stories of linkage analysis have the characteristic of mendelian disease, of which Huntington disease is the...
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Mims pathogenesis of infectious disease - part 2 potx

Mims pathogenesis of infectious disease - part 2 potx

... N Engl J Med 307, 83 Mims, C.A (1981) Vertical transmission of viruses Microbiol Rev 45, 26 7 -2 86 Mims, C A (1995) The transmission of infection Rev Med Microbiol 6, 22 1 7 -2 22 7 Nataro, J P and Kaper, ... the pathogenesis of and host defence against microbial infection J Clin Pathol Mol Pathol 52, 22 0 -2 3O Ketley, J M (1997) Pathogenesis of enteric infection by Campylobacter Microbiology 143, 5 -2 1 ... these infections are self-limiting Despite their disease- 81 82 Mims" Pathogenesis of Infectious Disease causing differences, they have some common pathogenic strategies, in particular the mechanism(s)...
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Tài liệu Health and Safety in the Child Care Setting: Prevention of Infectious Disease pdf

Tài liệu Health and Safety in the Child Care Setting: Prevention of Infectious Disease pdf

... Health and Safety in the Child Care Setting: Prevention of Infectious Disease A Curriculum for the Training of Child Care Providers Module Second Edition Developed by The California Child Care ... preventing the spread of disease in their child care setting Assist providers in establishing, developing and promoting written policies regarding health and safety in their child care setting Help ... 15 hours of health and safety training—eight hours for CPR and First Aid and seven for prevention of infectious disease and injuries The training in prevention of infectious disease is estimated...
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Chapter 054. Skin Manifestations of Internal Disease (Part 2) ppt

Chapter 054. Skin Manifestations of Internal Disease (Part 2) ppt

... is also important to examine the skin carefully for a migration of the erythema and associated secondary changes such as pustules or erosions Migratory waves of erythema studded with superficial ... Gener alized, Wax- but like Skin biopsy Isotre tinoin or perifollicular characteristic keratoderma acitretin; papules "skip" methotrexate areas Excl of normal ude skin cutaneous T cell lymphoma ... Locati Othe Diag Treat on of Initial r Findings nostic Aids ment Lesions Psori asisa Pink- Elbow red, silvery s, scale, sharply scalp, demarcated Nail knees, dystrophy, biopsy Skin Topic al arthritis,...
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Báo cáo y học:

Báo cáo y học: "Determinants of late disease-stage presentation at diagnosis of HIV infection in Venezuela: A case-case compariso" ppt

... hindering access to HIVcare than cost of diagnosis and treatment Early diagnosis of HIV- infection has benefits for the patient, public health and the society as a whole Patients diagnosed at a ... decreasing trend for late presentation with increasing knowledge of HIV- transmission and awareness of the PNSIDA (Table 2) Awareness of existence and free availability of HIV testing was negatively ... association with late presentation at diagnosis Not-wanting-to-know their HIV- status could be related to fear for HIV- related stigma as well as to general coping strategies to deal with a possible...
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Mims pathogenesis of infectious disease - part 3 pps

Mims pathogenesis of infectious disease - part 3 pps

... being professional phagocytes, are particularly important Uptake by these cells is a necessary first step in infection of the liver The types of 133 134 Mims' Pathogenesis of Infectious Disease ... Mims" Pathogenesis of Infectious Disease 92 OXYGEN-DEPENDENT ,/ Hexose monophosphate shunt: glucose-6-phosphate dehydrogenase (G6-PD) ,,, 05 + NADP++ H+ Superoxide i 02+OH-+ IOH" I_ 05 l- , ... of the tripartite anthrax toxin is a zinc metallo-protease which is potently cytotoxic for macrophages (see Ch for a fuller discussion of some of these toxins) 111 112 Mims" Pathogenesis of Infectious...
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Mims pathogenesis of infectious disease - part 4 ppsx

Mims pathogenesis of infectious disease - part 4 ppsx

... expression of interleukin-2 (IL-2) and interferon-y (IFN-y) and fail to produce IL -4 , IL-5 or IL-10 In contrast, Th2 cells produce IL -4 , IL-5 and IL-10, but not IL-2 or IFN-y In terms of their ... (TGF-~) is a potent inhibitor ofT- and B-cell proliferation Other cytokines such as IFN-y inhibit IL -4 activation of B cells, whereas IL -4 and IL-10 155 156 Mims" Pathogenesis of Infectious Disease ... i;z; -I- C o ~ -I- +o ee ~ o ~D O O O O O ~ ~.~ r "~ c~'~ c~ , c~ o c~ c~ c~ i-i c~ r o o r ~ r~ o cD c~ c~ c~ o ,.Q c~ b.O 4- a o 158 Mims' Pathogenesis of Infectious Disease ~ Antigen-binding...
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Mims pathogenesis of infectious disease - part 7 doc

Mims pathogenesis of infectious disease - part 7 doc

... allowing us to delineate 2 97 298 Mims' Pathogenesis of Infectious Disease Table 8 .7 Production of diarrhoea by microorganisms shed in faeces Infectious agent Diarrhoea Site of replication Rotaviruses ... site of infection 323 324 Mims" Pathogenesis of Infectious Disease Complement-assisted neutralisation of viruses In the case of viruses coated with antibody, complement adds to the mass of molecules ... is endemic, individuals immune to one type of dengue becoming infected with a related strain of virus They 2 87 288 Mims" Pathogenesis of Infectious Disease are not protected against the second...
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Mims pathogenesis of infectious disease - part 9 doc

Mims pathogenesis of infectious disease - part 9 doc

... ( 199 9) Immune recognition of foreign DNA: A cure for bioterrorism Immunity 11, 12 3-1 29 Liu, M A ( 199 8) Vaccine developments Nature Med Vaccine Suppl 4, 51 5-5 19 McGhee, J R and Mestecky, J ( 199 0) ... November 199 3) References Ada, G L ( 199 3) Towards phase III trials for candidate vaccines Nature (Lond.) 364, 48 9- 4 90 ASM News ( 199 3) Vaccine linked to rare adverse health effects ASM News 59, 54 7-5 48 ... resistance to disease depends to some extent on the 399 400 Mims' Pathogenesis of Infectious Disease type of infection In the case of systemic infections with an incubation period of a week or...
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Mims pathogenesis of infectious disease - part 10 ppt

Mims pathogenesis of infectious disease - part 10 ppt

... phagosome 107 inhibition of adsorption to cell surface 10 1-2 462 Mims' Pathogenesis of Infectious Disease Phagocytosis contd avoidance, microbial strategies -contd inhibition of chemotaxis 9 9-1 01 lysosome ... 20 5-6 role in recovery of infections 32 4-7 therapeutic potential 32 6-7 types 205, 32 4-5 viruses interfering with 327 Interleukin-1 (IL-1), fever pathogenesis 32 9-3 0 Interleukin-6 (IL-6), fever pathogenesis ... transmission 6 0-2 , 61 vaccine 37 3-4 see also Neisseria gonorrhoeae G proteins 89 450 Mims' Pathogenesis of Infectious Disease Gram-negative bacteria bacilli 41 7-1 8 cell wall 94, 104 , 203, 26 7-8 immune...
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báo cáo khoa học:

báo cáo khoa học: " Shared pathways to infectious disease susceptibility?" ppt

... result in broad, general susceptibility to multiple infectious diseases Elucidation of the respon­ sible genes and pathways often yields considerable insight into disease mechanisms and pathogenesis, ... establishing the etiology of certain autoimmune diseases where infectious diseases have long been suspected - but not confirmed - to be a predisposing factor For example, in the case of type diabetes, ... identification (or confirmation) of genes associated with susceptibility to the infectious diseases studied so far [15-18] Infectious disease genes identified via the GWAS approach have thus far been...
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