Computational modeling of cell signaling dynamics hypothesis management and parameter estimation methods applied to the akt pathway
Computational modeling of cell signaling dynamics hypothesis management and parameter estimation methods applied to the akt pathway
... being modeled often contain poorly understood aspects Further, the temporal dynamics of cell signaling pathway is complex and unintuitive, as the dynamics of proteins in the pathways are often interdependent ... state -of- the- art parameter estimation techniques Chapter Four has a special role in bridging the topic of “data-rich parameter estimation in Chapter Three to the topic of modeling of Akt phosphorylation ... bias in hypothesis evaluation This method was applied the parameter estimation work (Section 3.3) and a more indirect use of the method was applied to the Akt modeling study (Section 5.3) The fourth...
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Báo cáo khoa học: " Taxonomical impact of morphological variation in Quercus robur and Q petraea: a contribution to the hybrid controversy" pps
... Quercus robur L and Q pe(Matt) Liebl: a multivariate approach to the hybrid problem Data acquisition analysis and interpretation Watsonia 12, 81-101 Rushton BS (1983) An analysis of variation of traea ... 18 and 25 mm in sessile oak This variation covers about 60% of the trees classified here as pedunculate oaks and only 30% of the sessile oaks The question arises as to whether the variation in ... 2M) allows the 279 trees to be divided into two large (1 and 2) and one small group (3) (fig 1) .In table I, the mean values are indicated for each of the groups, and the F-values of the variance-analytical...
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Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx
... role of miRNAs with respect to the complicated regulation of the transcriptome and signal transduction Although miRNAs and well-established cell signaling pathways have been the subject of recent ... have focused upon the role of miRNAs in regulatory network of various cell signaling pathways We summarize the current knowledge of the interdependence of miRNA and cell signaling pathways, which ... dme-miR-8 Wnt signaling pathway Fig Involvement of miRNAs in various signaling cascades Many miRNAs are under the control of various conserved signaling pathways and in turn regulate components of these...
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Báo cáo khoa học: "Word Maturity: Computational Modeling of Word Knowledge" docx
... illustrates resulting word maturity curves for some of the words (" !"#$%&'()#*(+% merging using Procrustes Alignment, the comparison of word meanings becomes a simple problem of comparing word vectors ... schools, including: o Words known by most children in grade o Words known by 40-80% of children in grade o Words known by 40-80% of children in grade o Words known by fewer than 40% of children in grade ... all of the senses of a homograph word before the word can be considered fully known More specifically, one would expect the timeto-maturity of homographs to have greater values than words of similar...
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Protein s nitrosylation and its relevance to redox control of cell signaling
... of various redox signals into an effective second messenger system It is likened to phosphorylation/dephosphrylation process mediated by kinases and phosphatases since the process of S- nitrosylation ... blood and tissue and thus NO2˙- is thought to serve as part of NO˙ storage system in biological systems (Lundberg JO and Weitzberg E, 2005 & 2010) NO˙ storage system consists of free NO˙, NO2˙- and ... macrophages and neutrophils in the process called respiratory burst This persistent overproduction of ROS/RNS cause DNA lesions such as single strand break, double strand break and oxidized bases (eg...
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MODELING OF ESTUARINE WATER QUALITYINTRODUCTION Estuarine water quality is a term used to describe doc
... disregarded as a wastewater source Mass discharge coefficients relating to quality of the runoff water to the land use and amount of rainfall are given in Table Miscellaneous waste discharges occur into ... storm water runoff from the streets and gutters which is routed to the nearest waterway by storm water pipes, or it may consist of a mixture of storm water runoff and sanitary sewage in what is called ... floor of the river rises above sea level This is also the point at which a major change in water quality occurs from the ocean and estuary type water quality to that of the river This geographical...
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báo cáo khoa học: " Three-dimensional reconstruction of cell nuclei, internalized quantum dots and sites of lipid peroxidation" docx
... nuclei, of chromatin distribution and of sites of lipid peroxidation in cells undergoing oxidative stress by nanoparticles Chromatin reorganization in cell nuclei and lipid peroxidation are critical ... and (b) of Fig Discussion In this study we present a versatile, simple and suitable approach to 3-D reconstruction of intracellular QD location and of changes in nuclear morphology and lipid peroxidation ... MCF-7 and PC12 cells We also describe effective methods for 3-D reconstruction, visualization and quantification of nuclei and QDs We discuss two specific approaches to segmentation and 3-D reconstruction...
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Báo cáo y học: " Antibody microarray analysis of cell surface antigens on CD4+ and CD8+ T cells from HIV+ individuals correlates with disease stages" ppt
... lack of activation and expression of CD38 and HLA-DR on CD4+ T cells correlates with long-term non-progression [9] The enumeration of CD4+ T- lymphocytes by flow cytometry is used routinely in the ... infection [41] These findings, together with ours, support the hypothesis that the CD8+ T cells from LNTP may have stronger cytotoxic activity than those from other HIV+ individuals CD16 expression ... previously reported findings from flow cytometric investigations, but also demonstrated the power of the antibody microarray technology, by identifying new cell surface antigens that may potentially...
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Báo cáo y học: "Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study" docx
... model, a multidisciplinary approach and a specific team played a key role for education and for providing an early and appropriate sepsis management A large number of patients and a more detailed assessment ... contributions to study conception and design, acquisition of data, statistical analysis and has been involved in drafting the manuscript LD has made substantial contributions to study conception and design ... of an in-hospital educational program on sepsis (see below) and only the first episode of severe sepsis/ septic shock was considered in each patient The management of patients was evaluated by...
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Exact modeling of multiple access interference, ber derivation and a method to improve the performance of UWB communication systems
... Niranjayan, A Nallanathan and B Kannan, Modeling of Multiple Access Interference and BER Derivation for TH and DS UWB Multiple Access Systems , IEEE Transactions on Wireless communications, Aug ... Schemes”, Proc of Joint UWBST and IWUWBS 2004, May 2004 [3] S Niranjayan, A Nallanathan and B Kannan, A New Analytical Method for Exact Bit Error Rate Computation of TH-PPM UWB Multiple Access Systems , ... Of PIMRC 2004, September 2004 [4] S Niranjayan, A Nallanathan and B Kannan, Exact Modeling of Multiple Access Interference and BER Derivation for TH-PPM UWB , WCNC 2005, Accepted for publication...
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Từ khóa: a comparative study of parameter estimation methodsa comparative study of parameter estimation methods for statistical natural language processingproject management and process improvement methodsthe discovery that micrornas mirnas are synthesized as hairpincontaining precursors and share many features has stimulated the development of several computational approaches for identifying new mirna genes in various animal speciesmodeling of ring resonatorsa computational treatment of sentencecomputational aspects of mgrammarsstochastic modeling of languagea computational theory of prosestylea computational theory of perspectivea general computational treatment of comparativesa computational model of referencea computational theory of dispositionsa computational treatment of koreantowards a computational treatment of superlativesBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘI