... positions 17 10 11 of the L gene of HPIV1 (Table 1) The mutations in Table were introduced into the HPIV1 antigenomic cDNA individually or in combinations to yield the panel of rHPIV1 viruses listed in ... EL, London WT, Murphy BR: Evaluation of bovine, cold-adapted human, and wild -type human parainfluenza type viruses in adult volunteers and in chimpanzees J Clin Microbiol 19 91, 29 :11 75 -11 82 The ... 17 0HNT553ALY942A and rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 vaccine candidates reached peak titers of 7.9 and 7.2 log10 TCID50/ml, respectively, in Vero cells (Figure 1) The level of 17 0HNT553ALY942A...