Interaction between the elements with different degrees of smallness in nonlinear oscillating systems

Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

... 3A) and ATP (Fig 3B) in the absence and presence of curcumin, using the coupled enzyme assay In Fig 3A, the half-maximal activation of the ATPase by Ca2þ was measured in the absence of and in the ... appear unlikely that curcumin can ‘occlude’ ATP binding, in the same way as chromium -ATP, by trapping the ATP in the binding site when the two domains come together [44], as our ATP binding data shows ... absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e inhibiting the ATPase in a ‘competitive...

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Báo cáo Y học: The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin pot

... by tropomyosin 18 ± Interaction of the myosin light chain N-terminal peptide with actin and reversal by the TnI inhibitory peptide The effect of the IP on the interaction with F-actin of the myosin ... out so as to explore any influence of tropomyosin on the inhibitory region of TnI The binding affinity of the myosin loop peptide hcM398–414 to F-actin and F-actin tropomyosin was initially determined ... peptide The arginine residues of the IP are located in the central portion of the region associated with inhibitory activity Interaction of the cardiac inhibitory peptide region with F-actin To investigate...

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Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf

... subdomain AR3)13 in N/C interaction and the role of individual amino acid residues in and flanking the 23 FQNLF2 7motif in AR16)36 in N/C interaction Yeast protein interaction assays indicated that AR3)13 ... E., Brinkmann, A.O & Trapman, J (1997) Functional in vivo interaction between the amino- terminal, transactivation domain and the ligand binding domain of the androgen receptor Biochemistry 36, ... ligand-dependent interaction between AR NTD and AR LBD, N/C interaction, was studied in yeast and mammalian in vivo protein interaction systems, and in Ó FEBS 2002 Interaction between androgen receptor subdomains...

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Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf

... interaction between the N- and C-terminal domains of SSIII in vitro Mapping of the CD-binding region in the N-terminal SBDs In order to identify the SBD region required for the SBD–CD interaction, ... evidence indicating that two regions, D(316–344) in the D2 domain and D(495–535) in the D3 domain, are involved in the interaction with CD, and that this interaction enhances the catalytic activity of ... intramolecular interactions between the N-terminal SBDs and the C-terminal CD, and their effect on the regulatory properties of SSIII To investigate this, we used the full N-terminal region of...

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Báo cáo khoa học: Investigation of the interaction between the atypical agonist c[YpwFG] and MOR docx

... optimization of the complexes [33,34], providing a more detailed description of the binding mode and the electronic and steric properties of the c[YpwFG] ligand Results Synthesis and pharmacological ... contacts between the backbone carbonyl oxygen of the Tyr1 ˚ group and Oe2Glu229 (TMH V, 3.22 A) and OThr220 ˚ , and the last bidentate hydrogen bond of 3.30 A between the Oe1 and Oe2Glu310 (EL-3) and ... 12), whose interaction with OR has been the subject of intense investigation [50,51] In particular, the key interaction between the ligand and the receptor was determined to be the ionic interaction...

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Báo cáo khoa học: An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein pot

... the tag and the remainder of the protein and that the solution structure of MNK5 is not sensitive to the presence of the tag Recombinant protein characterization, NMR frequency assignments and solution ... interaction of the chaperone with the second domain seems unlikely also in the case of ATP7B The selectivity, if any, for the interaction of one of the six metalbinding domains with the chaperone ... interaction between HAH1 and two different soluble domains of ATP7A: the second (MNK2 hereafter) and the fifth (MNK5 hereafter) The solution structure of both the apo- and copper(I)- form of MNK2 was already...

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the interaction between the frequency of market quotes spread and volatility in forex

... presented They reveal an interesting feature In the last part of the day BST time, from about the closing time of the European exchanges and until the closing time of the New York exchange, volatility ... dummies, is the return in activity after the Tokyo lunch-break and around Interaction between quotations, spread, and volatility in FOREX 383 Fig Graphs of volatility, average spread, and number of quotations ... documented Others are already well known in markets, for example, the rise in spreads and decline in activity on Fridays But we were surprised by the finding of the continuing high volatility, in both...

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Báo cáo khoa học: "Effect of β -mercaptoethanol or epidermal growth factor supplementation on in vitro maturation of canine oocytes collected from dogs with different stages of the estrus cycle" ppsx

... [25,29], gonadotrophin [15] or steroid hormone [15] The present study investigated the effect of βME or EGF supplementation on the base of the stages of the estrus cycle of the ovaries, and demonstrated ... was only observed in the oocytes collected from the follicular stage In conclusion, supplementation of canine IVM medium with GSH-synthesis stimulator, β- ME or EGF improved IVM of canine oocytes ... oocytes collected from the Effect of β- mercaptoethanol or epidermal growth factor supplementation on canine oocytes follicular stage, consistent with the result from Takahashi et al [32] in bovine...

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