research on the etiology of ventilator associated pneumonia and preventive effect of continuously subglottic secretion drainage
Báo cáo y học: "Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators"
... original work is properly cited.ResearchMedical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparatorsMarin ... design, analysis of results, interpretation of findings, and drafting of the paper.Independent statistical analysis. The accuracy of the data analysis was inde-pendently verified by William ... statisticallysignificant.DiscussionThe results of this pooled analysis of two phase III studies indicated that initial use of doripenem in patients with VAP was associated with shorter durations of mechanicalventilation...
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Báo cáo khoa học: Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase pot
... DNA,to investigate the kinetics and substrate specificity of several known OGG1 polymorphic variants and phosphomimetic Ser fi Glu mutants. Amongthe polymorphic variants, A288V and S326C displayed ... compilation ê 2009 FEBS Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase Viktoriya S. Sidorenko1, Arthur P. ... bulk and charge of phosphoserine [40].In this article, we analyze the activity, substrate specificity and kinetics of two naturally occurring poly-morphic variants of OGG1, OGG1-A288V and OGG1-D322N,...
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Báo cáo khoa học: "developments in the redrying and storage of prechilled beechnuts (Fagus sylvatica L.): effect of seed moisture content and prechilling duration" docx
... years of storage. In the case of beechnuts, the key is in prechilling at acontrolled moisture content which permits the breaking of dormancy without allowing the germination. ... ability of prechilled seeds during 3 years of storage. The germination capacity of beechnuts was tested just after prechilling, after prechilling and drying down to 8 %, and ... A damaging effect of dry-ing was observed when the moisture content of the seeds during prechilling was high (34 %) and the duration long (X+6). When prechilling was...
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Quantitative evaluation of motor function before and after engraftment of dopaminergic neurons in a rat model of Parkinson''''s disease ppt
... Quantitative evaluation of motor function before and after engraftment of dopaminergic neurons in a rat model of Par-kinson's disease Journal of Biomedical Science 2010, 17:9 Chuang et al. Journal ... gait changes in rats after unilateral 6-OHDA lesioning and dopaminergic neuron grafting. Some of the dynamic and static parameters were altered in ratswith 6-OHDA-induced lesions including paw ... and reproduction in any medium, provided the original work is properly cited.Research Quantitative evaluation of motor function before and after engraftment of dopaminergic neurons in a rat...
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Báo cáo y học: "Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia" ppt
... incidence, aetiology and diagnosis of VAP, and addresscurrent therapeutic options. ReviewBench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial ... ventilated patients, the clinicaldiagnosis was correct in 62% of cases and therapeutic treatment plan was appropriate in only 33% of cases.Given the difficulty in diagnosing pneumonia in the ventilatedpatient ... by supine position and by upper airway and gastrointestinal intubation;aspiration in mechanically ventilated patients occurs around the outside of the endotracheal tube rather than through the lumen....
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Báo cáo khoa học: "Effect of ventilator-associated tracheobronchitis on outcome in patients without chronic respiratory failure: a case–control study" docx
... impact of VAT on outcome [31].ConclusionVAT is associated with increased duration of mechanical ven-tilation and ICU stay in immunocompetent nontrauma patients without chronic respiratory failure. ... afterinitiation of mechanical ventilation were included. 'Cases' areVAT patients, and 'controls' are patients without VAT. Trache-obronchitis was defined using all of the following ... of mechanical ventilation longer than median (14 days) in patients with (cases) and without (controls) ventilator-associated tracheobronchitis Factor Univariate analysis Multivariate analysisNumber...
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Báo cáo y học: "Combination therapy versus monotherapy: a randomised pilot study on the evolution of inflammatory parameters after ventilator associated pneumonia [ISRCTN31976779]" pot
... 2ResearchCombination therapy versus monotherapy: a randomised pilot study on the evolution of inflammatory parameters after ventilator associated pneumonia [ISRCTN31976779]Pierre Damas, Christophe Garweg, ... inflammatory parameters and duration of ventilatory support, and mortality as a secondary outcome. The a priori hypothesis is that synergistic action of combination therapy will accelerate the ... receiving antibiotics, among others. If this study failedto demonstrate any advantage of combination therapy overmonotherapy, the use of empirical combination therapy remains probably relevant in patients...
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Báo cáo y học: "Diagnosis of ventilator-associated pneumonia: a systematic review of the literature" docx
... bacteriological data in improving the accuracy of a clinical diagnosis of VAPMany studies have evaluated the value of bacteriological datain establishing the diagnosis of VAP compared to pathologi-cal, ... Analg 2001, 92:442-447.47. Prekates A, Nanas S, Argyropoulou A, Margariti G, Kyprianou T,Papagalos E, Paniara O, Roussos C: The diagnostic value of gram stain of bronchoalveolar lavage samples ... value of cytological characteristics of the available bronchoalveolar specimens in diagnosing VAP.These characteristics include the number of inflammatory cellsand Gram stains. The rapid availability...
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Báo cáo y học: "The paradox of ventilator-associated pneumonia prevention measures" doc
... doubles the risk of dying and increasesintensive care length of stay by a mean of 6 days [11].The explanationThe source of this paradox lies in the ambiguity andinaccuracy inherent in VAP ... Alternatively, VAP may be more of a marker for severity of illness in intubated patients ratherthan an independent source of morbidity in and of itself.Either way, the failure of multiple clinical ... obscures detection of an impact of prevention measures on bona fide pneumonias.Together, these effects create the possibility of the paradox wherea prevention measure may have a large impact...
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Báo cáo y học: "Value and price of ventilator-associated pneumonia surveillance as a quality indicator" potx
... http://ccforum.com/content/14/1/403doi:10.1186/cc8189Cite this article as: Aardema LM, et al.: Value and price of ventilator-associated pneumonia surveillance as a quality indicator. Critical Care 2010, 14:403.Page 2 of 2 ... The paradox of ventilator-associated pneumonia prevention measures. Crit Care 2009, 13:315.3. Curtis JR, Cook DJ, Wall RJ, Angus DC, Bion J, Kacmarek R, Kane-Gill SL, Kirchho KT, Levy M, ... Ligtenberg JJ, Spanjersberg R, Van der Werf TS: Ventilator-associated pneumonia: caveats for benchmarking. Intensive Care Med 2004, 30:996-997.Aardema et al. Critical Care 2010, 14:403 http://ccforum.com/content/14/1/403doi:10.1186/cc8189Cite...
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Báo cáo y học: "Paradoxical ventilator associated pneumonia incidences among selective digestive decontamination studies versus other studies of mechanically ventilated patients: benchmarking the evidence base" doc
... Paradoxical ventilator associated pneumonia incidences among selective digestive decontamination studies versus other studies of mechanically ventilated patients: benchmarking the evidence base. ... AccessParadoxical ventilator associated pneumonia incidences among selective digestive decontamination studies versus other studies of mechanically ventilated patients: benchmarking the evidence baseJames ... similar not only to each other, but to the benchmark and also to the VAP-IP’s of control groups of studies of other prevention methods. The fifth issue is that the quality scores of the studies asrated...
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Báo cáo y học: "Clara cell protein in bronchoalveolar lavage fluid: a predictor of ventilator-associated pneumonia" pot
... AccessClara cell protein in bronchoalveolar lavage fluid: a predictor of ventilator-associated pneumonia?Marijke J Vanspauwen1, Catharina FM Linssen1*, Cathrien A Bruggeman1, Jan A Jacobs1,4, ... infectionresulted in increased pulmonary and systemic inflamma-tion. Mechanical ventilation itself may at least partly beresponsible for an increase in CC-10 concentrations in all intubated patients. We hypothesise ... Early-onset VAPwas defined as VAP occurring within 7 days after intuba-tion, whilst late-onset VAP was defined as VAP occurringmore than 7 days after intubation [13,25].Collection of clinical dataCollected...
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Báo cáo y học: "Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa" pps
... evaluated the impact on the outcome of a monotherapy or a com-bined therapy in patients with PA-VAP. They s howedthat the initial use of a combination therapy significantlyreduced the likelihood of ... inappropriate antimicrobial therapy on the prognosis might be due to the high severity of patientsat VAP onset (SOFA at 6 in median in the presentstudy).As any delay in the initiation of an adequate antimi-crobial ... 15:R112http://ccforum.com/content/15/2/R112Page 7 of 10 RESEARCH Open AccessImpact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosaCatherine...
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RESEARCH ON METHOD FOR GEODETIC MONITORING, ANALYZING FOUNDATION AND BASEMENT DEFORMATION OF HIGH RISE BUILDINGS IN THE CONSTRUCTION PERIOD
... high- rise buildings. 4- Developing the software for analyzing the deformation of the foundation and basement of the high- rise buildings. 4. Method of research Method of research consists of ... deformation of foundation and basement of the high- rise buildings; Researching the combination of method of surveying and using sensing to increase the quality and effectiveness of monitoring the deformation ... evaluating and modeling the displacement process of the foundation and basement of the high- rise building in the construction period. - Object of research is: the method of monitoring, analyzing deformation...
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research on the etiology of ventilator associated pneumonia and preventive effect of continuously subglottic secretion drainage
... conduct the study: Research on the etiology of ventilator associated pneumonia and preventive effect of continuously subglottic secretion drainage Objectives:1. To determine the bacterial etiology ... hospital -associated pneumonia (HAP) and ventilation -associated pneumonia 1.1.1 .Etiology of HAP and VAP Etiology of HAP and VAP varies among geographical areas, study time, study subjects, and invasive/non-invasive ... tract and eventually causes pneumonia. This mechanism has led to an idea of removal of the secretions to prevent VAP. In a controlled trial, Mahul has evaluated the efficiency of continuous subglottic...
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