Báo cáo y học: "Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development" potx
Báo cáo y học: "Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development" potx
... hormone and many of the environmental stress signaling pathways that we haveexamined. These new findings suggest most aspects of plant physiology are influenced by the circadian system and willhelp ... genes is Circadian co -regulation of metabolic pathwaysFigure 5 Circadian co -regulation of metabolic pathways. (a) Metabolic pathways for the production of the key intermediate geranylgeranyl diphosphate ... Biology 2008, 9:R130Open Access2008Covingtonet al.Volume 9, Issue 8, Article R130ResearchGlobal transcriptome analysis reveals circadian regulation of key pathways in plant growth and developmentMichael...
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Báo cáo y học: "Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes" doc
... cycle'. As indicated several cyclins (cyclin A1,cyclin A2, cyclin B1, cyclin B2, cyclin D1, cyclin D2, and cyclinE1) are downregulated in the ES cell derived cardiomyocytes.Fully differentiated ... oxygen intensively [22], a constant supply of oxygen is indispensable for sustaining cardiac function and viability. This notion is well elucidated by our analysis, indi-cating that genes involved ... participate in key biologic signal trans-duction pathways. Interestingly, five genes belonging to the category 'negative regulation of Wnt receptor signaling pathway' and four genesbelonging...
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Báo cáo y học: "Global expression changes resulting from loss of telomeric DNA in fission yeast" pps
... day 12 of the growth curve, thegene-expression profiles of survivors became relatively con-stant and remained so through day 15. The profiles of days 12-15 appear most similar to days 1 and ... heterochromatin forma-tion away from centromeres and the mating-type locus [53]. In a separate study, telomeric silencing of a reporter gene and binding of Swi6 at the telomere were not affected in dcr1-,ago1- ... strainsAfter germination of G4 and growth of spores at 32°C forthree days on YEA plates [18], plates were stored at 4°C whilethe genotypes of random colonies were determined. A portion of single...
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Báo cáo y học: " Comprehensive transcriptome analysis of mouse embryonic stem cell adipogenesis unravels new processes of adipocyte development" ppt
... a nd 5). Interestingly, theearly steps of a dipocyte development in mESCs a recharacterized by a dramatic gain of scores of TFs, manyFigure 4 Status of the Wnt pathway and effect of exogenous ... the early steps of adipocyte formation involv eimportant changes in cell signaling, including compo-nents of the Wnt pathway. Of these, we have furtherinvestigated the role of a single candidate, ... cephalic WAT in mouse [26].Finally, we performed an integrated study compilingTFBS enrichment results, gene expression profiling and PPI analysis. In terestingly, th ree motifs enriched in clus-ter...
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Báo cáo khoa hoc:" Global Transcriptome Analysis of Bacillus cereus ATCC 14579 in Response to Silver Nitrate Stress" pot
... classes of cell motility (N), translation (J) and hypothetical proteins. Interestingly, transcripts encoding proteins of transport and metabolism (P) (such as inorganic ion, amino acids, carbohydrate, ... collection, analysis and interpretation of data and wrote the paper. JS carried out the computational analyses of sRNA. PG provided research support and involved in drafting and revising the manuscript ... equivalent cell density and inoculated into LB-soft agar (0.4% agar) plates and incubated at 37°C overnight. Competing Interest The authors declare that they have no competing interests. Author’s...
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Báo cáo y học: "Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity" pps
... determined using SAM [23]. Probes wereannotated using the Web-based Affymetrix NetAffx analysis tool [56] and Ingenuity Pathway Analysis (Ingenuity, Moun-tain View, CA).NIA microarray sample and data ... cells/well. Expansion was done bytrypsinizing (0.05% trypsin, Cellgro) the cells and replatingthem every 2 days at a density of 100-200 cells/cm2. Cells atpopulation doubling of more than 80 were used ... depletedusing a MACS separation CS column, and cells replated at 10cells/well. Expansion was done by trypsinizing (0.05%trypsin) the cells and replating them every 2 days at a density of 200 cells/cm2....
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Báo cáo y học: "Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression" pptx
... (3'UTRs) of the messages. Many of the characterizedmiRNAs are involved in developmental regulation, includingthe timing and neuronal asymmetry in worm; growth control and apoptosis in fly; brain ... orNRSF) plays a fundamental role in regulating neuronal geneexpression and promoting neuronal fate [1,2]. REST containsa zinc-finger DNA-binding domain and two repressordomains interacting with ... phosphorylation by multiple extracellular stimulisuch as neurotrophins, cytokines, and calcium, as well as avariety of cellular stresses. The discovery of regulation of mul-tiple miRNAs by CREB indicates...
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Báo cáo y học: " The Opossum genome reveals further evidence for regulatory evolution in mammalian diversification" doc
... segments defyconventional methods of sequencing and assembly and understandably lag behind the determination of euchromaticsegments. They include, for example, Y- chromosomesequences that remain an ... providing valuable insights into the patterns of structural and regulatory genome evolution within and between each of these groups. Eventually, the integration of sequence data with phenotypic information ... interesting and potentiallyinformative with the addition of new genomes, some of which are already on their way, including those of amonotreme (the platypus Ornithorhynchus anatinus) and another marsupial...
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Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"
... Justice,A.C., Covinsky,K.E ,Berlin,J.A. Assessing the gener-alizability of prognostic information. Ann. Intern. Med. 1999; 130: 515 - 524. 23. Feinstein AR, Walter SD, Horwitz RI. An analysis of Berkson's ... same type of analy-sis, but with the primary care and hospital controls are shown in Tables 6 and 7, respectively. The inter-action [CA 19.9 x AGE] is in Table 8. The “bootstrap” analysis ... http://www.medsci.org 46 The values obtained for the Kolmo-gorov-Smirnov test (study of normality of continuous variables) are shown in Table 3. Table 3. Normality Analysis of the Continuous Variables. Kolmogorov-Smirnov...
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Báo cáo y học: "γ A novel mechanism for the regulation of IFN-γ inducible protein-10 expression in rheumatoid arthritis" ppsx
... within inflamed joints appears to be reg-ulated not only by inflammatory cytokines but also by thephysical interaction of activated leukocytes with FLSs.Once expressed, IP-10 probably plays ... T, Strieter RM: The role of chemokines in inflammatory joint disease. J Leukoc Biol 1996,58:6-12.2. Choy EHS, Panayi GS: Cytokine pathways and joint inflamma-tion in rheumatoid arthritis. ... of Th1-typecells into the joint. Thus, the aim of the present study wasto examine the regulatory mechanisms of IP-10 expressionby synovial inflammatory cells and fibroblasts, especiallyby...
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