... improve the ability of BLAST to search for
structural homology of a query sequence to a known protein
structure or a family of proteins. This tool searches for the
structural alphabet high-scoring ... basis, and effective and reliable search capabilities) and employs a kappa-
alpha (κ, α) plot derived structural alphabet and a new substitution matrix...
... The
study monitor of the LCC includes the patient in CAP-
NETZ by applying the following criteria: age ³ 18 years, a
pulmonary infiltrate diagnosed by chest x-ray, clinical
symptoms consisting of ... study. The study was approved by the local eth-
ical committee. Our study was not an intervention study
with implementation of standardized criteria for the diag-
nosis and therapy of...
... fying
the phosphorylation of protei ns of the cytoskeleton [44].
As well as decreasing pro-inflammatory cytotrafficking
(cytokines and NO synthesis) [10], acidification and
phosphorylation and, in consequence, ... analog scale, and electrodermal activity (EDA). At necropsy (Week 8), macroscopic and
histomorphological analyses of synovium, cartilage and subchondral bone of t...
... 2002 Cytochrome c structure and stability (Eur. J. Biochem. 269) 3361
and structure analyses of bacterial cytochromes c, including
HT c-552 and PA c-551.
MUTAGENESIS STUDIES FOR
STABILITY
In general, ... Yamazaki, K., Kyogoku, Y. &
Kobayashi, Y. (1998) Solution structure of thermostable cyto-
chrome c-552 from Hydrogenobacter thermophilus determined by
1
H-NMR spectros...
... L. Juliano Structural Bioinformatics Core Facility, University of North Carolina, Chapel Hill, NC 27599, USA
3
Division of Rheumatology, University of Pennsylvania School of Medicine and Philadelphia ... extremely disordered
proteins: implications for the etiology of systemic autoimmunity
Philip L Carl
1
, Brenda RS Temple
2
and Philip L Cohen
3
1
Department of Pharmacol...
... inducing
anti-inflammatory cytokines or neutralizing pro-inflammatory
cytokines should be critically evaluated before considering
this form of therapy.
Depletion of neutrophils significantly reduced the severity of
CAIA ... multicellular
inflammatory process, including infiltration of lymphocytes
and granulocytes into the articular cartilage, proliferation of
synovial fibroblasts...
... of Groups A and
B at study days 14 and 28, for Group C subjects at study days
28 and 42, and for Group D subjects at study days 70 and 84.
Healthy male or female subjects (aged 18–65 years inclusive)
with ... serotypes, and approximately 25% of subjects
responded to at least six different serotypes by day 14 (Figure
5a) and by day 28 (Figure 5b).
Table 3
Geometric means...
... (HMFN0839)* 1-Acylglycerol-3-phosphate O-acyltransferase 9 [GenBank:NM_032717.3
]
34 MTHFD2 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2,
methenyltetrahydrofolate cyclohydrolase
[GenBank:NM_006636.3
]
35 ... Diseases (NIAID), Cooperative Center for Translational Research on Human Immunology and Biodefense, Baylor Institute for
Immunology Research and Baylor Research I...
... morphogenetic and
functional defects by promoting the death of
erythrocytes and the endocardium in zebrafish
embryos
Yi-Ting Wu
1
, Che Yi Lin
1
, Ming-Yuan Tsai
2
, Yi-Hua Chen
3
, Yu-Fen Lu
3
, ... induction of apoptosis of endocardium and erythrocytes. In addition, this study further demonstrates
the importance of endocardium and hemodynamic forces on heart morphogenesis a...
... tomography myelography visual-izing only a part of the rootletsFigure 3
Axial view of computerized tomography myelography visual-
izing only a part of the rootlets.
Publish with BioMed Central and ... visualization of the
rootlets and orientation of the exact level of the root. Sensitivity and specificity for coronal and
oblique coronal views of unrecognition of intr...