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Báo cáo y học: "An annotated cDNA library and microarray for large-scale gene-expression studies in the ant Solenopsis invicta" pot

Báo cáo y học:

Báo cáo y học: "An annotated cDNA library and microarray for large-scale gene-expression studies in the ant Solenopsis invicta" pot

... those involved in other interestingbehaviors and traits. Unfortunately, in ants such studies havebeen seriously constrained by the lack of sequence data and other molecular tools. The majority ... research interactions informationOpen Access2007Wanget al.Volume 8, Issue 1, Article R9MethodAn annotated cDNA library and microarray for large-scale gene-expression studies in the ant Solenopsis ... relative to the Drosophila genome. Alternatively, these gene categoriesmay simply be biased in cDNA libraries relative to genomes, for instance, because they contain mainly highly or mainlylowly expressed...
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Báo cáo y học: "Dipeptidyl peptidase IV activity and/or structure homologs: Contributing factors in the pathogenesis of rheumatoid arthritis" doc

... strongly reduced in RA, and splitting patient samples into non-inflammatory and inflammatory by C-reactive protein levels reveals the reduction is predominantly observed in inflammatory RA [55].Although ... high in RA patients [8,57]. As the methotrexate- and deoxyco-formycin-based therapies act as anti-inflammatory agents byincreasing extracellular adenosine and blocking ADA,respectively, the ... in the synovium infiltrate, strongly express the chemokine receptorsCXCR3, CXCR4, CXCR6 and CCR5, which all bind pro-inflammatory chemokines. SDF-1 is important for retainingcells in the inflamed...
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Báo cáo y học: "Pro/con debate: Should antimicrobial stewardship programs be adopted universally in the intensive care unit" potx

... teaching hospital reported a 37% reduction in the number of days of unnecessary antibiotics use by decreasing the duration of treatment and by reducing new starts [25]. In another study, antimicrobial ... signifi cant change in clinical thinking to reduce our dependence on and abuse of antibiotics is needed.Antimicrobial stewardship programs form only one strategy for minimizing the incidence ... escalating, with systemic antibiotics being the single most costly drug class over the past decade in non-federal hospitals in the United States. In 2007, systemic antibiotics accounted for 11.2%...
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Báo cáo y học: "An ovine tracheal explant culture model for allergic airway inflammation" pot

... airways and in their responses in culture for 24 h. Importa ntly, this study establishes the potential for the application of tracheal explant cultures in relevant ex vivo investigations on the therapeutic ... 2006,24:147-174.28. Marini M, Vittori E, Hollemborg J, Mattoli S: Expression of the potentinflammatory cytokines, granulocyte-macrophage-colony-stimulatingfactor and interleukin-6 and interleukin-8, in bronchial ... epithelium and underlying lamina propria(Figure 1I-L). No positive staining within th e epitheliumwasseenintissueat0h,whilesomestainingwaspre-sent in the underlying lamina propria. Staining of apop-totic...
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Báo cáo y học:

Báo cáo y học: " An ovine tracheal explant culture model for allergic airway inflammation" potx

... in the loss of the mucus layer overlying the epithelium.Mast cells are required for the development of allergicreactions, with cross-linking of the high affinity recep-tors for IgE resulting ... epithelium and underlying lamina propria(Figure 1I-L). No positive staining within th e epitheliumwasseenintissueat0h,whilesomestainingwaspre-sent in the underlying lamina propria. Staining of apop-totic ... 2006,24:147-174.28. Marini M, Vittori E, Hollemborg J, Mattoli S: Expression of the potentinflammatory cytokines, granulocyte-macrophage-colony-stimulatingfactor and interleukin-6 and interleukin-8, in bronchial...
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Báo cáo y học: "A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset" pot

... account for the choice for the underlying concept in the first place.ConclusionWhen comparing the results of studies, one must consider dif-ferences in case-mix, in insulin therapy, in other ... associatedtherapies, in the power of the analysis and in outcome meas-ures. The latter was the focus of this paper. The ambiguity and variability in the definitions of indicators and the threshold ... and morbidity is well known from the literature. Hence, hypergly-caemia reduction forms the main goal of TGC. Surprisingly,only nine studies explicitly defined a hyperglycaemic event and employed different...
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Báo cáo y học: "An ETP model (exclusion-tolerance-progression) for multi drug resistance" pptx

... to the dysfunction of ion-transporting proteins,cell swelling and lysis and associated with the release ofinflammatory mediators) [11].RationaleTherefore, it is hypothesized that the formation ... distinct and mul-tifactorial entity culminating in the failure of therapeuticregimens in clinical oncology. From the clinical perspec-tive, the emergence of drug resistance is determined by the rate ... leading to mortality.Figures 2, 3 and 4 summarize the hypothesis advancedhere; they depict the scheme of events following chemo-therapeutic treatment and the significance of the two dis-tinct...
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Báo cáo y học: " An immune reaction may be necessary for cancer development" ppt

... benefit, not for the benefit of the host.Therefore the system was probably selected, at least ini-tially, to be helpful and even stimulating to the foreigninvaders when these arrived in small ... reactivity werereduced. Other tumor types, such as mammary cancers and rectal carcinomas, usually find the reduced immunecapacity in the kidney-transplant patient to be even fur-ther from their ... immunity is, in the case of most tumors, veryunlikely. For a rather different view of the role of immunity in can-cer, see the review by Robert D. Schreiber [35].Competing interests The author(s)...
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Báo cáo Y học: RING finger, B-box, and coiled-coil (RBCC) protein expression in branchial epithelial cells of Japanese eel, Anguilla japonica pot

Báo cáo Y học: RING finger, B-box, and coiled-coil (RBCC) protein expression in branchial epithelial cells of Japanese eel, Anguilla japonica pot

... Biotech), and 2.5 units of Taqpolymerase (Takara). The mixture was cycled first at 94 °C for 1 min, 36 °Cfor5 min ,and7 2 °C for 5 min followed by40 cycles at 94 °Cfor1min,60°Cfor2min ,and7 2°Cfor2 min. ... as they appear in freshwater and disappear in seawater [28,29]. The chloride cells are mainly located in the gill and involved in osmoregulation of teleost fish.Reflecting their extraordinary power ... agroup of zinc-binding proteins that belong to the RINGfinger family. They are so called because they have anN-terminal RING finger motif defined by one histidine and seven cysteine residues (C3HC4)...
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Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt

Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt

... (underlined basesdenote the functional core of the MREs and the Sp1 bindingelement, and the mutated bases are indicated by italictype).Western blot analysis The MREa-binding proteins purified ... sequencing on the two proteins, the purified protein bands were blotted onto apolyvinylidene difluoride membrane, and the individualproteins were subjected to N-terminal sequencing. The N-terminus ... that the lack of the dimerizationdomain in the DKu-80 cDNA decreased the WD promoteractivity in a dominant-negative manner. These resultssuggest that Ku-80 protein is an important factor in the regulation...
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