... functions of each transcription factor
group in dendritic patterning of type I DA neurons in the Drosophila
peripheral nervous system. Subtypes of DA neurons have simple and
stereotyped branching patterns ... phenocopy of the RNAi phenotype, validating the
accuracy of the approach. Analysis of the mutant flies
revealed that some of the candidate genes are also involved...
... the
facilitatory effect of tidal inspiration on genioglossus pre
activation tended to be higher in OSAS than in controls
also with a preferential increase in UA muscles excitability
during inspiratory loading ... excitability changes
Facilitatory maneuvers modify TMS responses by increas-
ing synaptic excitability at either the motor cortex and/or
the spinal motoneurons [29] (or, in...
... negatively regulate integration
[116,117]. This is seen with both integrating and non-
integrating virus, thereby effectively regulating superin-
fection at the level of integration rather than entry
[117]. ... that seen in productive infec-
tion using wild type virus. Thus, the activity of Nef was
not linked to integration in regards HLA class I modula-
tion, a finding confirmed in...
... in
2003. The lines were inbred by 20 generations of full-sib
inbreeding to create 340 inbred lines. Locomotor reactivity
for each of the inbred lines was measured by randomly
assigning the lines ... reactivity than the control line. Of these genes, four
have been previously implicated to affect activity: muscle-
blind mutants are paralytic [36]; Amphiphysin [37] and
Cysteine string...
... and the induction of ethanol
tolerance [30]. Induction of ethanol tolerance was completely
abolished in flies carrying both null mutations in hang and in
the gene encoding tyramine β-hydroxylase ... human
orthologue RAB11 family interacting protein 4
(RAB11FIP4)).
Alcohol-induced fatty acid biosynthesis is well documented in
heavy drinkers and leads to alcohol induced fatty liver...
... termination and increased mRNA stabi-
lity by RNA-binding proteins are involved in the regu-
lation of gene expression in eukaryotes and their
viruses [135,136]. A thorough investigation of these
processes ... modified by the presence of a hydroxy-
methylated, glucosylated moiety at cytosine position 5.
This modification places a large, bulky group within the
major groove, making it...
... played by specific domains in
the corresponding transcription factors during in vivo
erythroid and megakaryocyte development.
Erythroid Kruppel-like factor (EKLF)
This zinc finger protein plays ... Whang-
Peng,J.&Haynes,B.F.(1984)Conversionofastemcellleukemia
from a T-lymphoid to a myeloid phenotype induced by the ade-
nosine deaminase inhibitor 2¢-deoxycoformycin. Proc. Natl Acad.
Sci....
... Wathelet
1
1
Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati;
2
Department of
Molecular and Cellular Biology, Harvard University, Cambridge, MA
Virus infection ... functionally unable to
Correspondence to M. G. Wathelet, Department of Molecular and
Cellular Physiology, University of Cincinnati College of Medicine,
231 Al...
... Aec2
contain genes that control development of SjS.
In the present study, the investigators produced recombinant
inbred lines by crossing the C57Bl/6 and C57Bl/6.NOD-
Aec1Aec2 strains. A recombinant inbred ... exocrino-
pathy in the NOD mouse and by reducing one of these regions
considerably, Nguyen et al. in a recent issue of Arthritis Research
and Therapy propose candidate gen...
... JA, Benbow U, Vincenti MP, Sporn MB, Brinck-
erhoff CE: A synthetic triterpenoid selectively inhibits the
induction of matrix metalloproteinases 1 and 13 by inflamma-
tory cytokines. Arthritis ... Griswold
DE: Pharmacological profile of SB 203580, a selective
inhibitor of cytokine suppressive binding protein/p38 kinase,
in animal models of arthritis, bone resorption, endotoxin
shock...