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Báo cáo y học: "Mobile DNA: genomes under the influence" docx

Báo cáo y học:

Báo cáo y học: "Mobile DNA: genomes under the influence" docx

... members of the recently discoveredSVA family of elements, a relatively new player on the primate retrotransposon scene, had promoted the duplica-tion and dispersal of the AMAC gene family in the lineage ... probably await discoveryin other eukaryotic genomes. Transposable elements co-opted As with other host-parasite systems, the promiscuity andlong-term coevolution of transposable elements with the host ... withincoding regions and are precisely spliced out after translationby their own encoded enzyme. They may represent anextreme example of parasitic targeting strategy. Althoughthese elements were once...
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Báo cáo y học: "HLA-DR regulation and the influence of GM-CSF on transcription, surface expression and shedding

... until day 14. The densitometry values for mRNA of the healthy controls were compared to the values of the septic patients on each day. Figure 1 shows HLA-DR mRNA for septic patients monocytes was ... and synovial fluid in hyperinflammatory states [9] and in vitro experiments have shown that the inflammatory cytokine IFN-γ induced shedding of HLA-DR by human monocytes [10]. However whether ... Microbiology and Immunology from University of Leeds, and PhD in Immunology from University of Liverpool, where she worked on the expression of HLA-DR and the characterisation of the monocyte in...
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Báo cáo y học: "Promise and pitfalls of the Immunochip" docx

... nitive studies are awaited, and they may be tagged by SNP studies anyway [4]. Most heritability studies report narrow-sense heritability, which is heritability excluding gene–gene interaction; ... an unlikely source of much missing heritability. Of the 95 loci known by SNP studies at the end of 2009 to be associated with Crohn’s disease and type 1 and type 2 diabetes, only three harbored ... survival/health, or if they are removed from populations by natural selection. Rare variants may also have higher genetic resolution, helping to pinpoint the key regions underlying genetic associations.Current...
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Báo cáo y học: " HIV-1 Nef: at the crossroads" docx

... immunodeficiency virus type 1(HIV-1) by the glycoprotein of vesicular stomatitis virus tar-gets HIV-1 entry to an endocytic pathway and suppressesboth the requirement for Nef and the sensitivity tocyclosporin ... interact with the cytoplasmictail of MHCI [41]. However, a ternary complex betweenNef, the cytoplasmic tail of MHCI and AP1 has beenrecently demonstrated separately by the Collins and the Guatelli ... toactivate a cryptic tyrosine sorting signal in the cytoplasmictail of MHCI and diverts newly synthesized MHCI mole-cules from their transit to the plasma membrane to aninternal compartment in the paranuclear...
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Báo cáo y học: "Godoy & Godoy technique in the treatment of lymphedema for under-privileged populations."

... compression on the vessels; the au-thors suggest the use of the term ‘myolymphokinetic therapy’ when these activities or exercises result in a volumetric reduction of the limb. These exercises ... Godoy JMF, Godoy MFG, Batigalia F. Preliminary evaluation of a new, more simplified physiotherapy technique for lymphatic drainage. Lymphology 2002;35:91-3. 2. Godoy JMP, Braile DM, Godoy MFG. ... utilizing the RAGodoy® device to treat lymphedema of the lower extremi-ties. Journal of Phlebology and Lymphology 2009; 2(1):22-25. 8. Godoy MFG, Godoy JMP, Braile DM. Dynamic analysis of muscular...
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Báo cáo y học: "HIV DNA and Dementia in Treatment-Naïve HIV-1-Infected Individuals in Bangkok, Thailand"

... the current study attempts to address the question whether a spe-cific PBMC subset (M/MФ or CD4 lymphocytes) har-bors HIV DNA. We undertook the current study to test the hy-pothesis that HIV ... beginning therapy. In the prior study, our data sug-gested that HIV DNA was predominantly in CD14/CD16 M/MФ [15]. Therefore to further assess the importance of CD14/CD16 phenotype, the current ... lymphocytes, was isolated with beads; with the remaining cells separated into CD14+/CD16+ by enrichment and bead separation. An aliquot of the sorted cells was then analyzed by flow cytometry...
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Báo cáo Y học: Mitochondrial DNA deletion mutations A causal role in sarcopenia docx

Báo cáo Y học: Mitochondrial DNA deletion mutations A causal role in sarcopenia docx

... along the length of the 1000 lm. The smallest (minimum CSA)value of the fiber CSA in the ETS abnormal region wasdivided by the average value of the fiber CSA in the ETSnormal region within the ... genomes were the only mtDNA genomes detected in the ETS abnormal regions while onlywild-type genomes were found in the ETS normal regions.LCM coupled with PCR analysis has clearly demonstratedthat ... represented by the black bars using the left axis, fiber number is represented by the white bars using the rightaxis, muscle cross-sectional area is represented by the width of the black bars using the...
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Báo cáo Y học: Thermodynamics and kinetics of the cleavage of DNA catalyzed by bleomycin A5 A microcalorimetric study pdf

Báo cáo Y học: Thermodynamics and kinetics of the cleavage of DNA catalyzed by bleomycin A5 A microcalorimetric study pdf

... DNA catalyzed by bleomycin A5(BLM-A5) in the presence of ferrous ion and oxygen. The molar reaction enthalpy for the cleavage, the Michaelis–Menten constant for calf thymus DNA and the turnovernumber ... BamHIendonuclease. By comparing the molar enthalpy change for the cleavage of calf thymus DNA induced by BLM-A5withthose for the scission of calf thymus DNA mediated byadriamycin and by (1,10-phenanthroline)-copper, ... enzyme-catalyzed reaction was proposed and employedto produce not only the thermodynamic constant (DrHm)but also the kinetic properties (Kmand k2) of the cleavage ofDNA catalyzed by...
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Báo cáo y học: " Detecting DNA regulatory motifs by incorporating positional trends in information content" pdf

... Using the double exponential or normal distribution for the priorcorresponds to using a certain type of penalty in the likeli-hood. In these two cases, the penalty function takes the formof the ... of the number ofstarting points on the algorithm; and second, the effect of λ on the ability of the algorithm to detect the known binding sitesin the data.As previously discussed, we use the ... to find the motif that maximizes the likelihood of the data given the model. Because of the many local maxima in the likelihoodfunction, the number and type of starting points used for the EM...
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Báo cáo y học: "Two different genomes that produce the same result" docx

... formation of the stalk and the synthesis of a purple dye in the spore mass. Both species aggregate by chemotaxis toward sources of cAMP. The high synchrony of development makes these experiments ... that suppressed the effect of the first) with another round of mutagenesis, restoring lysozyme activity. e amino acids encoded by the DNA between the two mutations should, in theory, have been ... very first, but nearly 45 years ago, George Streisinger and his colleagues mutated the lysozyme gene of phage T4 with acridine, which they knew caused frameshifts, and then they caused a second...
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