... ±Birkprotease inhibitors [5], metallothioneins [6], prothymosina [7], a bacterial ®bronectin-binding protein [8], the brainprotein a-synuclein together with the related proteinsb-synuclein and c-synuclein ... elicalconformation. There may also be some b strand in some of the proteins, espec ially b-andj-casein judging b y the well-de®ned negative ROA bands in these proteins in the range» 1245 cm)1, ... relies mainly on the evidence outlined above. In view of the c lose similarity of the ROA spectra of the casein, synuclein and tau proteins shown in t his paper, wehave reproduced in F ig. 1...