... mice were pro-duced by a deletion in the IL-10 gene in a cross of C57BL/6 × 129/ Ola (originally provided by W Müller, Institute of Genetics, Cologne, Germany). They were further back-crossed ... scores.Among mice of the QD strain, individuals that subsequentlydeveloped cyanosis lost as much as 25% of their bodyweight within a few days after the onset of respiratorysymptoms (Fig. 1). Major weight ... scores. However, the symp-toms in these strains did not proceed in relapses as theydid in the QD and B10.Q mice, and therefore resulted in alower mean score than for the other strains (Fig. 1c).Table...