... formation of gamma glutamyl-lysine bonds [4].Furthermore, tTG plays a role in the transduction of extracellular signals, mediated by its additional GTP-hydrolyzing activity [5], analogous to that of ... member of a family of seven isoforms of enzymesinvolved in protein cross-linking, including prostatic TGaseand factor XIII. tTG is a Ca2+-dependent ubiquitousintracellular enzyme that catalyzes ... H2O2and TMB.Fig. 2. Western blots of 12 purified tTG fragments. (A) Primary antibody, mAb His-probe. (B) Primary antibody, mAb CUB 7042. Secondaryantibody, goat anti-(mouse Ig) conjugated with...