... study and after 12 and24 months, using vaginal ultrasonography and cytology. E2in serum was measured (approximately 12 hours after tablet intake) by radioimmunoassay (Clinical AssaysTM,DiaSorin, ... Kameda T, Mano H, Yuasa T, Mori Y, Miyazawa K, Shiokawa M,Nakamaru Y, Hiroi E, Hiura K, Kameda A, Yang NN, Hakeda Y, Kumegawa M: Estrogen inhibits bone resorption by directlyinducing apoptosis ... osteoblastic cell line with high levels of estrogenreceptors. J Bone Miner Res 1996, 11:193-199.23. Tamura T, Udagawa N, Takahashi N, Miyaura C, Tanaka S,Yamada Y, Koishihara Y, Ohsugi Y, Kumaki...