... [22]and antigen-induced arthritis [23] induces amelioration of the arthritis. Of the many mediators of inflammation, mactinin is the firstexample of a fragment of a cytoskeletal component thatmight ... thawed, dialyzed against phosphate-buffered saline, and centrifuged again; the total samplevolume was then applied to a column of immunoaffinity-purified antibody covalently bound to a Affi-Gel ... process and the low concentration of mactinin needed for activity make it necessary to assayat least 1 ml of fluid, and this amount is not available fromany tissue and fluid bank. However, mactinin...