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Báo cáo y học: "Exogenous glucagon-like peptide-1 attenuates the glycaemic response to postpyloric nutrient infusion in critically ill patients with type-2 diabetes" ppsx

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Báo cáo y học: "Mactinin: a modulator of the monocyte response to inflammation" pps

... [22]and antigen-induced arthritis [23] induces amelioration of the arthritis. Of the many mediators of inflammation, mactinin is the firstexample of a fragment of a cytoskeletal component thatmight ... thawed, dialyzed against phosphate-buffered saline, and centrifuged again; the total samplevolume was then applied to a column of immunoaffinity-purified antibody covalently bound to a Affi-Gel ... process and the low concentration of mactinin needed for activity make it necessary to assayat least 1 ml of fluid, and this amount is not available fromany tissue and fluid bank. However, mactinin...
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Báo cáo y học: "Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis" ppt

... prostaglandin E synthase (PGES) and cyclooxygenase (COX) isoenzyme mRNAs in chondrocytesEffects of cytokines on the expression of prostaglandin E synthase (PGES) and cyclooxygenase (COX) isoenzyme mRNAs ... triplicate experi-ments, and representative results from three independentTable 1Oligonucleotide primers used in the reverse transcription-polymerase chain reactionTarget gene encoding Product length ... prostaglandin E synthase (PGES) and cyclooxygenase (COX) isoenzymes in chondrocytes stimulated with interleukin-1β (IL-1β)Time course of the expression of prostaglandin E synthase (PGES) and cyclooxygenase...
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Báo cáo y học: " Presence and utility of IgA-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis: the Swedish TIRA project" docx

... article Presence and utility of IgA-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis: the Swedish TIRA projectAnna Svärd1,2, Alf Kastbom2, Åsa Reckner-Olsson2 and ... poorresponse to TNF inhibitors [20]. The aim of the present studyis to analyse to what extent IgA-class antibodies to anti -cyclic citrullinated peptides (IgA anti-CCP) occur in recent-onset RA and how they ... anti-CCP = IgG-class antibodies against cyclic citrullinated peptides; RA = rheumatoid arthritis; RF = rheumatoid factor; SE = shared epitope; TIRA = Early Intervention in Rheumatoid Arthritis; TNF...
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Báo cáo y học: " Whey protein isolate attenuates strength decline after eccentrically-induced muscle damage in healthy individuals" pptx

... RESEARC H ARTIC LE Open Access Whey protein isolate attenuates strength decline after eccentrically-induced muscle damage in healthy individualsMatthew B Cooke1,2†, Emma Rybalka1†, Christos G Stathis1†, ... Hayes1*†AbstractBackground: We examined the effects of short-term consumption of whey protein isolate on muscle proteins andforce recovery after eccentrically-induced muscle damage in healthy ... all essential amino acids tomaximise the increase in protein synthesis duringrecovery.Conclusion In summary, the major finding of this investigation wasthat whey protein isolate supplementation...
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Báo cáo y học: " Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis " pps

... fromnegative to +++ within each filter.Results The diversity of the autoantibody repertoire in cryptogenic fibrosing alveolitis In order to determine the specificity and diversity ofautoantibodies in patients ... commentary review reportsprimary researchPrimary research Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis Cleo Robinson, ... epitopes in the protein [14]. Interestingly, the authors of that study noteda correlation between the type of epitope and the diseaseduration, supporting the hypothesis that the autoantibodyresponse...
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Báo cáo y học: "Serum cystatin C concentration as a marker of acute renal dysfunction in critically ill patients" doc

... to creatinine clearance (C Cr)Relationships of (a) serum creatinine and (b) serum cystatin C to creatinine clearance (C Cr).Figure 2The (a) inverse of serum creatinine (1/creatinine) and ... http://ccforum.com/content/9/2/R139R139April 2005 Vol 9 No 2ResearchSerum cystatin C concentration as a marker of acute renal dysfunction in critically ill patientsPatricia Villa1, Manuel Jiménez1, Maria-Cruz Soriano1, ... can increase as GFRdecreases. All of these factors explain why serum creatinine concentration may not be a good parameter for accuratedetermination of GFR, especially at lower rates [1].Cystatin...
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Báo cáo khoa học: "Peripheral arterial blood pressure monitoring adequately tracks central arterial blood pressure in critically ill patients: an observational study" ppt

... peripheral and central mean arterial blood pressures are interchangeable in critically ill patients. Totest our hypothesis we compare simultaneous measurementsof arterial blood pressure in peripheral ... sampling of arterial blood [1]; and the need to changethe insertion site of the arterial line. Fever and suspicion ofcatheter-related infection were the main reasons to changethe arterial insertion ... evaluated to determine the interchange-ability of peripheral and central mean arterial blood measure-ments. We focused the analysis of interchangeability on mean arterial pressure because the...
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Báo cáo y học: "Pro/Con debate: Is procalcitonin useful for guiding antibiotic decision making in critically ill patients" pdf

... and integration of clinical findings into decision- making processes.Patients with severe pancreatitis who developed infectivenecrosis or multiorgan dysfunction showed a sustainedincrease in ... identified[24], making the point that PCT is better used as a tool tostratify risk in the clinical context than specifically as a binaryindicator. A large epidemiological study is required in intensive ... results! The Danish Procalcitonin Study Group is conducting an RCT of a PCT-guided strategywith mortality endpoints in critically ill patients (NCT00271752)[26]. A French study is looking at another...
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Báo cáo y học: " Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts" docx

... reproduction in any medium, provided the original work is properly cited.AbstractIntroduction Postischemic injury to the coronary vascular endothelium, in particular to the endothelial glycocalyx, mayprovoke ... of coronary vascular leak andinterstitial edema and a tendency to forestall both no-reflow anddegradation of the endothelial glycocalyx. IntroductionMyocardial damage and coronary microvascular ... organblood flow, to activation of coagulatory and inflammatory path-ways, and to tissue edema. Investigating strategies for protect-ing the endothelial glycocalyx against disruption obviously...
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Báo cáo y học: "Fluid balance as a biomarker: impact of fluid overload on outcome in critically ill patients with acute kidney injury" potx

... fluid balance has on clinical outcomes in critically ill adults with AKI [1]. In a secondary analysis of the SOAP(Sepsis Occurrence in Acutely Ill Patients) study, Payen andcolleagues [1] examined ... crucial, and RRT should ideally be initiated as earlyand safely as possible [19]. As a minimum, all critically ill patients should have an estimate of baseline ‘dry’ weight anddetermination of ... severe acute kidney injury. J Crit Care 2008 [Epub ahead of print].18. The VA/NIH Acute Renal Failure Trial Network: Intensity of renalsupport in critically ill patients with acute kidney injury....
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Báo cáo y học: " influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients" potx

... citation purposes)Vol 12 No 4Research Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage ... days; P = 0.045).Conclusion The AOX intervention did not reduce early organ dysfunction but significantly reduced the inflammatory response in cardiac surgery and trauma patients, which may ... aimed at testing the hypothesis that the early administration of an AOX micronutrient combination includingselenium would improve clinical outcome in selected groups of critically ill patients...
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Báo cáo y học: "Acute fluid shifts influence the assessment of serum vitamin D status in critically ill patients" pps

... 25(OH )D 3: 25-hydroxy vitamin D3 ; 1a,25(OH)2 D 3: 1,25-dihydroxy vitamin D3 .AcknowledgementsWe would like to acknowledge the role of Goce Dimeski and the laboratorystaff in the Department of Chemical ... our findingsTo our knowledge this is the first study to examine the effects of volume loading on serum vitamin D concen-trations. Our data clearly demonstrate the impact of fluid loading on serum ... blood by the Vitamin D binding protein(VDBP) to the liver where it undergoes 25 hydroxylationto form 25(OH )D 3,which in turn undergoes 1a hydro-xylation (especially, but not exclusively in the...
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Báo cáo y học: "Exogenous glucagon-like peptide-1 attenuates the glycaemic response to postpyloric nutrient infusion in critically ill patients with type-2 diabetes" ppsx

... on the glycaemic response to small intestinal nutrient infusion in critically ill patients with pre-existing type-2 diabetes.Methods: Eleven critically ill mechanically-ventilated patients with ... AccessExogenous glucagon-like peptide-1 attenuates the glycaemic response to postpyloric nutrient infusion in critically ill patients with type-2 diabetesAdam M Deane1,2,3*, Matthew J Summers2, Antony ... evaluate the effects of an acute, exogenous GLP-1 infusion (1.2 pmol/kg/minute) on the glycaemic response to a postpyloric nutrient infusion in critically ill patients with known type-2 diabetes....
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Báo cáo y học: " Prognostic value of circulating amino-terminal pro-C-type natriuretic peptide in critically ill patients" ppsx

... 15:R45http://ccforum.com/content/15/1/R45Page 6 of 10 RESEARCH Open Access Prognostic value of circulating amino-terminal pro-C-type natriuretic peptide in critically ill patientsAlexander Koch, Sebastian ... NT-proCNP in critically ill patients was indeed correlated with endogenous insulinlevels (C -peptide) as well as serum resistin and retinol-binding protein 4, two mediators of insulin resistance(data ... article as: Koch et al.: Prognostic value of circulating amino-terminal pro-C-type natriuretic peptide in critically ill patients. CriticalCare 2011 15:R45.Submit your next manuscript to BioMed...
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