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Báo cáo y học: " Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia" ppsx

Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc

Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc

... level of the hasoperon containing the hyaluronan synthase gene or theprotein level of hyaluronan synthase. Solubilization of theenzyme from membranes of MU-treated cells and addition of the ... obtained using culturedhuman skin fibroblasts. It seems likely therefore that themechanisms of inhibition of HA synthesis by MU are verysimilar if not identical between eukaryote and prokaryotecells.Cell-free ... little involvement of MU-meta-bolites in the inhibition of HA synthesis by MU in FM100cells. These above results indicate that something requiredfor a fully functional HA synthesis system is...
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Báo cáo y học: "Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal" pot

... cloned into the BsrGI sites of the linearized pYES2yEGFP, resulting in the formation of pYES2yEGFP -IN (GFP -IN) , pYES2yEGFP-152 -IN (GFP-152 -IN) and pYES2yEGFP-180 -IN (GFP-180 -IN) . A GFP2-NLS -IN ... encoding the following combinations: GN -IN and GC -IN, GN -IN and GC-LEDGF, GN -IN and GC-linker (control), GN -IN and GC-Impα (importin α), GN-180 -IN and GC-Impα, GN-NLS -IN and GC-Impα, GN-152 -IN and ... using in vitro systems [23]-we focused on thenuclear import of IN protein using yeast and mammalianBinding of IN to importin α as estimated by an ELISA-based systemFigure 6Binding of IN to...
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Báo cáo y học: "Inhibition of early steps in the lentiviral replication cycle by cathelicidin host defense peptides" pptx

... conical polystyreneComparative analysis of inhibition of lentiviral and retroviral vector infectivityFigure 5Comparative analysis of inhibition of lentiviral and retroviral vector infectivity. Percent ... activity of stably transduced target cells. Specific inhibition of earlysteps of infection was only seen for the cathelicidin LL37 and PG-1. As an additional control for the specificity of inhibition, ... anti-HIVactivity on at least two levels: directly inactivating virusparticles; and affecting the ability of target CD4 cells toreplicate the virus [35-37]. Binding to gp120 of HIV-1 and inhibition of HIV...
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Báo cáo y học: "Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation" ppsx

... Histology, Microbiology and Medical Biotechnology, Histology Unit, Faculty of Medicine, University of Padova, Viale G. Colombo 3, 35121 Padova, Italy2Department of Cellular & Molecular Medicine, ... aftergrafting were mainly fibrocartilage or mixed(hyaline–fibrocartilage) tissue, while tissues taken fromasymptomatic patients were hyaline cartilage in 83% of biopsies. In a small group of asymptomatic ... and eosin staining. (b) Glycosaminoglycan (safranin-O) staining. (c) Collagen type I (immunohistochemistry). (d) Collagen type II (immunohistochemistry). (e) Polarized light microscopy.Arthritis...
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Báo cáo y học: "Development of daily rhythmicity in heart rate and locomotor activity in the human fetus" ppt

... development of rhythmicity during several years after birth [19,22,23].The Research Institute of Perinatal Medicine, Obstetrics and Gynecology has been conducting investigations onfetal rhythmicity since ... re-adjustment of fetalcardiac biorhythms during physiologic pregnancy. Abstracts of the 14th Congress of Obstetricians and Gynecologists: Problems of Perina-tology. Diagnosis and treatment of female infertility. ... healthy fetus at the gestationalage of 16–20 weeks has pronounced daily rhythms of theheartbeat and locomotor activity. The fetuses in which wefailed identify any distinctly expressed rhythms of...
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Báo cáo y học: "Profiling of cellular proteins in porcine reproductive and respiratory syndrome virus virions by proteomics analysis" pps

... host cytoskeleton system proteins, which havethe maximum profusion among the identified cellularproteins, including Actin, Ke ratin, Annexin, Coronin,Tubulin, Tropomyosin, and Cofilin. Enveloped ... pandemic in many swine-producingcountries and has become one of the most seriousthreats to intensive swine industry. In June 2006, theoutbreak of “ high fev er” in China, caused by highlypathogenic ... replication.According to our investigation, guanine nucleotide-binding proteins, tyrosine 3-monooxygenas e/tryptophan5-monooxygenase, peroxiredoxin 1 and galectin-1 pro-tein were first reported in P RRSV...
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Báo cáo y học: "Impact of rhinitis on airway inflammation: biological and therapeutic implications" ppsx

... hista-mine, vasodilation, increased permeability, and bron-choconstriction. This early phase is followed by a complexnetwork of inflammatory phenomena in which T lympho-cytes, cytokines and adhesion ... favour the rolling, extravasation, and migration towards the epithelium of inflammatory cells. Thekinetics of inflammation following allergen exposureinvolve the migration of inflammatory cells to ... G, Binks S, DahlenSE: Combined antagonism of leukotriene and histamine pro-duces a predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics. Am J Respir...
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Báo cáo y học: "Determinants of weaning success in patients with prolonged mechanical ventilation" ppsx

... periods of ventila-tion before weaning, high breathing frequency and trachealP0.1, minute ventilation, and persistently high PaCO2 and intrin-sic PEEP. They also found that the TTI remained in ... the study and participated in the collection of data and the drafting of the manuscript. PC participated in thestudy design and the collection and interpretation of data. GPparticipated in the ... control in abefore -and- after fashion and, more importantly, that employedthe recording of respiratory mechanics during a trial of spon-taneous breathing. This is particularly important since...
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Báo cáo y học: " End-of-life issues in the acute and critically ill patient" pdf

... refractory symptoms in dyingpatients. J Pain Symptom Manage 2008 in press.21. Castellano G: The criminalization of treating end -of- lifepatients with risky pain medication and the role of theextreme ... understanding of informed consent and the risks and benefits of the medical intervention[87]. Fol-lowing a validated systematic process minimizes physi-cian bias and standardizes the measurement of ... only in the states of Oregon and most recently Washington, and euthanasia is illegal in every state[93]. Euthanasia is, however, legal in somecountries, including the Netherlands and Switzerland.Interestingly,...
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Báo cáo y học: " Power-law-like distributions in biomedical publications and research funding" ppsx

... techniques include gene and protein expression analysis, protein-protein interactions, and high-through-put screening using overexpression and RNA interference methodologies.Historically unbiased ... resulted in qualitativelysimilar results.Understanding the function of all thegenes in the mammalian genome is agoal shared by researchers and fundingagencies alike. Success in achieving thisgoal ... literature) and research funding(measured by gene references in fundedgrants). This shows that the researchcommunity is still far from under-standing the function of all mammaliangenes, and instead...
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