... decided to continue using
this computerized protocol to avoid treatment-related
morbidity. Subcutaneous CGMS seems not good enough
in aiming for tight glucose regulation in the ICU.
Intravascular ... the CGMS system, however, when used in a
tight glucose regulation protocol – and adjusting the
insulin dose based on the subcutaneous readings – could
have severe...
... mLÆmin
)1
.
Enzyme assays
PCMT specific activity was determined, in vitro, in the
cytosol of erythrocytes subjected to oxidative stress, as
previously described [9,24]. Erythrocyte lysates were
obtained by ... two different erythrocyte age/density fractions obtained by
isopycnic centrifugation on a Percoll gradient. Methyl esterification in
intact erythrocytes was assayed by incubating t...
... subfamily of the cytoch-
rome P450 (CYP) enzymatic system, is responsible for
the metabolism of tacrolimus [10]. Specifically; tacro-
limus is mainly metabolized by CYP3A4 and CYP3A5
enzyme isotype. ... polymorphism. The alleles A and
G are CYP3A5*1 and CYP3A5*3, respectively. Indi-
viduals carrying at least one CYP3A5*1 allele express
CYP3A5 protein whereas individuals homozygotes
for C...
... dystrobrevin to function properly may depend on
its association with dystrophin. First, we refined the
dystrophin-binding region on dystrobrevin (Dyb-1) by
performing deletion-mapping experiments in vitro.Wethen
tested ... vitro.Wethen
tested the ability of t he truncated Dyb-1 proteins to bind to
dystrophin (Dys-1) in a yeast two-hybrid assay, as well as
their ability to rescue dy...
... that
2-deoxygalactose is toxic to wild-type yeast strains that
constitutively express galactokinase, due to the accumula-
tion of 2-deoxygalactose-1-phosphate [40]. Growth of a
wild-type strain bearing the CYC1::GAL1 ... Spring Harbor Laboratory, Cold
Spring Harbor. New York.
40. Platt, T. (1984) Toxicity of 2-deoxygalactose to Saccharomyces
cerevisiae cells constitutively synthesising...
... Du MH, Cuniasse P, Ny T, Hoylaerts MF, Millan JL:
Residues determining the binding specificity of uncompetitive
inhibitors to tissue-nonspecific alkaline phosphatase. J Bone
Miner Res 2004, 19:1862-1872.
Arthritis ... common finding that is fre-
quently associated with advanced OA. In contrast to general-
ized arterial calcification of infancy, in which hydroxyapatite
crystals are for...
... cytokine
receptors and phosphorylated on tyrosine residues by Janus
tyrosine kinases (Jaks) [76]. Interestingly, in addition to
tyrosine phosphorylation, STAT proteins in vertebrates can
also be phosphorylated ... et al.: A
protein kinase involved in the regulation of inflammatory
cytokine biosynthesis. Nature 1994, 372:739-746.
3. Ambrosino C, Nebreda AR: Cell cycle regulation by...
... Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
2
Laboratory for Statistical Analysis, SNP Research Center, RIKEN, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
Corresponding author: Shiro ... Sudo A, Miyamoto Y, Fukuda A, Mabuchi
A, Kotani A, Kawakami A, Yamamoto S, et al.: An aspartic acid
repeat polymorphism in asporin inhibits chondrogenesis and
increases susceptibility to oste...
... (pSS), especially in patients with anti-SSA or
anti-SSB antibodies, in a study including 111 Australian
patients with pSS and 156 controls [3].
The aim of our study was to investigate in a large case-control
study ... replication study had not been performed.
Conclusion
Our study illustrates the necessity to include a large number of
patients in genetic case-control studies. In...
... symp-
toms were exacerbated by walking and running and
partially relieved by elevation. She had to stop to rest after
30 minutes of walking because of intolerable pain.
There was neither history ...
Ahmet Nedim Yanat
Address: Dept. of Orthopaedics and Traumatology, Mustafa Kemal University, Faculty of Medicine, Antakya, Hatay, Turkey
Email: Teoman Toni Sevinç - sevinctt@mynet.com; Aydıne...