Báo cáo y học: " A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies" ppt

Báo cáo khoa học: "A Stochastic Language Model using Dependency and Its Improvement by Word Clustering" ppt

... Recognition, volume 12 of Mathematics in Science and Engineering. Accademic Press. 903 A Stochastic Language Model using Dependency and Its Improvement by Word Clustering Shinsuke Mori * Tokyo ... corpus The word- based 2-gram model for bunsetsu generation and the character-based 2-gram model as an unknown word model (Mori and Yamaji, 1997) are common to the POS-based model and class-based ... propose two complete stochastic language models using dependency between bugsetsu, a se- quence of one or more content words followed by zero, one or more function words, and evaluate their...

Báo cáo hóa học: " A Method for Assessment of Segmentation Success Considering Uncertainty in the Edge Positions" pptx

... while they are moving forwardalong a track. The repetitive line scanning and the movement of the strip make the acquisition of a rectangular image possible. The image obtained consists of a stream ... Generalization of discrepancymeasures in an edge Once the experienced operators have carried out the manual segmentation and the segmentations have been integrated toform the ideal segmentation ... uncertainty in the determination of the edge position even by experi-enced operators; therefore, in this situation the assess-ment method needs to take the uncertainty of the ideal segmentation into...

Báo cáo y học: "A human functional protein interaction network and its application to cancer data analysis" potx

... and its application to cancer data analysisGuanming Wu*1, Xin Feng2,3 and Lincoln Stein1,2 Functional protein interaction networkA high-quality human functional protein inter-action network ... FI network (Figure 1), and apply this network to thestudy of glioblastoma multiforme (GBM) and other can-cer types by expanding a human curated GBM pathwayusing our FIs, projecting cancer candidate ... of the proteins in thehand-curated GBM pathway. In this way we were able to extend the hand-curated pathway from 73 proteins and 187 interactions to 181 proteins and 768 interactions. Atotal...

Báo cáo y học: "A first genome assembly of the barley fungal pathogen Pyrenophora teres f. teres" ppt

... et al. Genome Biology 2010, 11:R109http://genomebiology.com/2010/11/11/R109Page 2 of 14 RESEARCH Open AccessA first genome assembly of the barley fungal pathogen Pyrenophora teres f. teres Simon ... characterization of the draft genome. Wehave complemented the assembly with the first cytoge-netic visualization and genome- wide genetic map forthis species.Results The genome of P. teres f. teres isolate ... P. teres f. teres pathogenicity.BackgroundNet blotch of barley (Hordeum vulgare) is caused by Pyrenophora teres Drechsler (anamorph Drechslera teres [Sacc.] Shoem.). P. teres is an ascomycete...

Báo cáo y học: "A possible connection between psychosomatic symptoms and daily rhythmicity in growth hormone secretion in healthy Japanese students" potx

... life rhythm, and melatonin secretion appears to be an important index ofcircadian rhythmicity. Based on our previous finding that growth hormone and melatonin exhibit similar daily rhythmicity [17], ... research.Conclusion Psychosomatic symptoms may be associated with circa-dian dysfunction, as inferred from blunted rhythmicity in growth hormone secretion. Competing interestsThe authors declare that they have ... 45:1235-1239. Daily variation in salivary level of growth hormone in the high and low self-assessment groupsFigure 1 Daily variation in salivary level of growth hormone in the high and low self-assessment...

Báo cáo y học: "A social marketing approach to implementing evidence-based practice in VHA QUERI: the TIDES depression collaborative care model" docx

... receiving the TIDES marketing materials,whether they felt the materials were compelling, andwhether they are referring patients to TIDES depression care managers.Discussion Collaborative depression ... about the challenges andbenefits of implementing TIDES. Frontline providers The TIDES collaborative care model can only succeed iffrontline providers in the clinics, especially primary care physicians ... mail). Finally, they are most likely to find mar-keting messages convincing when fellow providers,including clinicians like themselves or TIDES care manag-ers, deliver the message.VeteransTIDES...

Báo cáo y học: "A Canadian national survey of attitudes and knowledge regarding preventive vaccines." pptx

... a national survey to better under-stand the public's acceptance of current and potentialfuture vaccinations and to explore their attitudes and lev-els and types of knowledge. Methods Survey ... 3Department of Psychiatry, University of Toronto, Toronto, Canada, 4Division of Preventive Oncology, Cancer Care Ontario, Toronto, Canada, 5Division of Epidemiology, Biostatistics and Behavioural ... Murray D Krahn - murray.krahn@uhn.on.ca* Corresponding author preventive vaccinesattitudesknowledgenationwide Canadian survey AbstractBackground: Vaccines have virtually eliminated many diseases,...

Báo cáo y học: "A novel preclinical model for rheumatoid arthritis research" pdf

... F, Yu X: A novel preclinical model for rheumatoid arthritis research. Arthritis Research & Therapy 2010, 12:148.Petersen and Yu Arthritis Research & Therapy 2010, 12:148 http:/ /arthritis- research.com/content/12/6/148Page ... Uchiyama Y, Yorozu K, Hashizume M, Moriya Y, Mihara M: Tocilizumab, a humanized anti-interleukin-6 receptor antibody, ameliorates joint swelling in established monkey collagen-induced arthritis. ... Collagen-induced arthritis in common marmosets: a new nonhuman primate model for chronic arthritis. Arthritis Res Ther 2010, 12:R200.2. Trentham DE, Townes AS, Kang AH: Autoimmunity to type II collagen...

Báo cáo y học: "A confocal microscopic study of solitary pulmonary neuroendocrine cells in human airway epithelium" ppt

... not for citation purposes)Respiratory ResearchOpen AccessResearchA confocal microscopic study of solitary pulmonary neuroendocrine cells in human airway epitheliumMarkus Weichselbaum1,2, ... occurring also in the cell body tovarying degrees. The variation exhibited in the morphol-ogy of the PNEC and its differing peptide profiles suggeststhat these cells may be in a dynamic state in ... respiratory tractfrom the trachea to the terminal airways [3]. In the fetallung they are frequently located at the branching points of airway tubules, and in humans are present by 10 weeksgestation...

Báo cáo y học: "A multivariate Bayesian model for assessing morbidity after coronary artery surgery" docx

... postoperative mortal-ity, not morbidity. In the present study, we developed andtested a Bayesian discrimination model for assessing morbid-ity risk after coronary artery surgery. Some practical ... http://ccforum.com/content/10/3/R94Page 1 of 13(page number not for citation purposes)Vol 10 No 3ResearchA multivariate Bayesian model for assessing morbidity after coronary artery surgeryBonizella ... and mortality risk after coronary artery bypass graft-ing. Ann Thorac Surg 1997, 64:1050-1058.12. Hartz AJ, Kuhn EM: Comparing hospitals that performs coro-nary artery bypass surgery: the effects...

Báo cáo y học: "A health economic model for evaluating a vaccine for the prevention of herpes zoster and post-herpetic neuralgia in the UK" ppsx

... £32,809/QALY gained respectively. Anothersensitivity analysis assumed a 10-year duration of full vaccine efficacy and, in addition, that 50% of the remain-ing healthy vaccinated population would ... assumptions of vaccine efficacy, testing the applied point estimate and duration of vaccine efficacy. The lower and upper limit of the 95%confidence interval of the vaccine efficacy obtained from the ... sup-port input data only to the detail of 5-year age bands, the analysis of a single age group resulted in nearly identicalICERs as that of the 5-year age group it falls within. For example, if a vaccination...

Báo cáo y học: "A tumor cord model for Doxorubicin delivery and dose optimization in solid tumors Steffen Eikenberry" ppsx

... significantinterest in modeling fluid flow and delivery of macromol-ecules within solid tumors [8-11]. Some modeling workhas considered spatially explicit drug delivery to solid tumors [12-14], ... DOX.Interestingly, binding to proteins affects DOX delivery dif-ferently in the plasma and extracellular tumor space.While increasing the fraction of bound DOX in theplasma inhibits delivery ... effects on delivery. Increasing diffusion for free DOX (DF) significantlyincreases drug delivery. Increasing diffusion for boundDOX (DB) actually inhibits delivery slightly and reducescell...

Báo cáo y học: " A reaction-diffusion model of the receptor-toxinantibody interaction" pot

... ular space. By solving numerically the system of non-linear PDEs of the model we managed to simulate a rich variety of reaction-diffusion processes that may occur in the RTA system. For various ... require a separate study. Such a study would include an application of a data fitting algorithm thataccounts for t he experimental data uncertainty as well as some additional assumptionsabout relationships ... instead of system of ODEs), which usually prevent any analytical progress and implies numericalsolutions. This was the main motivation for our approach to tackle the refined RTA model. The aim of...

Báo cáo y học: "A continuum mathematical model of endothelial layer maintenance and senescence" ppsx

... AccessResearchA continuum mathematical model of endothelial layer maintenance and senescenceYing Wang, Baltazar D Aguda and Avner Friedman*Address: Mathematical Biosciences Institute, and Department of ... model monitored the changes of the EC monolayer over a period of 60 years, with a discrete time step of 1 year. Dead ECscould be replaced either by division of surrounding ECs orby homing of ... number of mitoticdivisions until senescence is reached. The number of cells of generation i at time t in the area bounded by x and x +dx, and y and y + dy is defined to be mi(x, y, t)dxdy. For...

Báo cáo y học: " A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies" ppt

... CentralPage 1 of 19(page number not for citation purposes)Theoretical Biology and Medical ModellingOpen AccessResearch A multiscale mathematical model of cancer, and its use in analyzing irradiation ... details).The anti-growth, p53, pathway is activated in the case of DNA damage [18,19]. This is particularly relevant during irradiation [20]. p53 pathway activation can block the cellcycle and ... the irradiation dose is above Thr at any time, p53 isactivated and the cells are labeled as 'DNA damaged cells'.DNA damaged cells are identified at the R point of the cellcycle and...

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