... inhibittranscription.Functional significance of the HTLV-I TATAA element to transcriptional activation by TaxIn the course of our analyses, we noted that Tax can acti-vate the HTLV-I minimal TATAA-promoter without anyknown ... machinery to their promoters [52,53]. In yeast, artificial recruitment of TBP bypasses the effect of DNA-tethered activatorswhereas the activators fail to activate transcription whenphysically ... stimulus, are required for induction of apoptosis in T-cells. Retrovirology 2004, 1:7.43. Tanaka A, Takahashi C, Yamaoka S, Nosaka T, Maki M, Hatanaka M:Oncogenic transformation by the tax gene of...