Báo cáo y học: "4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study" doc
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Research
4G/5G polymorphism of
PAI-1
gene is associated
with multiple organ dysfunction and septic shock
in pneumonia ... allele of PAI-1
polymorphism have higher risk for multiple organ dysfunction syndrome and septic shock and in agreement they
showed more...
... stimulation Yes Yes NA No Yes Yes Yes NA No Yes
Sepsis Yes Yes Yes Yes Yes Yes Yes Yes Yes No
Dialysis Yes No No No No No No No No No
CS Yes No Yes Yes Yes Yes Yes 0 Yes Yes
AG Yes No No No No Yes No ... unit, which is a 17-bed ICU of a tertiary center with
approximately 750 admissions yearly. Inclusion criteria
consisted of intubation and mechanical ventilation,
hemodynamic stabili...
... associated with MA was interest-
ing and surprising. This finding was even more
surprising when considering that BE and lact ate, the cur-
rent metabolic markers used clinically to define tissue
hypoperfusion, ... shock state combined with injury produ ced only
an isolated reduction in MA without overt coagulopathy
by standard definitions.
One r eason for the lack of overt coa...
... between
nuclear and mitochondrial genes.
Localization of sense and antisense tags within gene
models and confounding effects of overlapping genes
The procedure used in creating the BGA should result
only in ... This observation, ba sed
on thousands of experimentally verified distinct genes,
suggests that this profile is reasonably accurate. This
profile is different from...
... examined
with CT scan and/ or open biopsy, and closely moni-
tored clinical and with MRI.
Clinical management for the PNF requires a multidis-
ciplinary approach and the use of a multi-speciality
Neurofibromatosis ... establish the significant
of this phenomenon.
Historically, PE was repaired with chondrosternal
resection, or some combination of cartilage incision and
ost...
... sections were developed with diaminoben-
zidine tetrahydrochloride (DAB) and counterstained with
hematoxylin. Immunohistochemical assay was per-
formed within 7 days of section preparation. To ...
in the cancer nest; (C) and (D): the staining of CD133 on the
luminal surface and the basal surface of cancer cells; (E): the
staining of CD133 on budding cancer nest; (F): the...
... staining; 1–4, weak staining; 5–8, moderate staining;
and 9–12, strong staining. For the purpose of statistical
analysis, the cohort was grouped into tumors with negli-
gible or weak staining ... followed by a further 3 cycles of
adjuvant 5-fluorouracil and cisplatin.
Of the 221 patients, 88 were referred for treatment from a
single institution following initial diagnosis of NPC...
... encoded by the ITGAV
gene, plays a key role in angiogenesis. Hyperangiogenesis is
involved in rheumatoid arthritis (RA) and the ITGAV gene is
located in 2q31, one of the suggested RA susceptibility ... factors
that remain to be discovered.
Since the association evidence is modest, no genetic testing
would be clinically indicated. Instead, the clinical relevance of
the f...
... 1-9 cover the symptoms of inattention; items 10-
18 the symptoms of hyperactivity and impulsivity. In
this study we used a continuous scoring method [32].
The MDQ is a screening instrument for ... there is a higher preva-
lence of depression and anxiety disorders than in the
general population [18-20].
The pathophysiology and genetics of ADHD probably
involve multiple...
... experiencing the stress of trauma,
critical illness or major surgery typically display endogenous
insulin resistance that is characterized by reduced insulin
uptake in peripheral tissues, along with ... parenteral
daily intake, enteral daily intake and total daily caloric intake. The
primary outcome measure was the incidence of BSI. Additional
endpoints were ICU length of stay,...