... methods of
hyperdynamic therapy and speci c endpoints vary
widely. A systematic review of clinical trials of the
various techniques of hyperdynamic therapy and
their e ects on cerebral ... hyperdynamic therapy are
most important.
Dankbaar and colleagues [1] provide a systematic
review of clinical studies of hyperdynamic therapy and its
components on...
... obtaining EB in children are therefore
limited. The potential to investigate the timing and natu-
ral history of RBM thickening, and other features of airway
remodelling in children, would be increased ... manually by using
electronic caliper endpoints (figures 1a and 1b). By esti-
mating the Hounsfield units using the ROI (region of
interest) tool, the endpoints were pl...
... quality of life after being in the ICU is
attributable to pre-existing disease. The importance of the effect of pre-existing disease is further supported by the
small, long term increment in the ... wi th the study
group who were healthy before the intensive care
period.
HRQoL among patients dying during the follow up
In total, 139 patients who were included in...
... to participate in the
synthesis of an as yet undefined secondary metabolite, was
induced in the rhizosphere.
Finally, it is worth noting the expression of genes pointing
towards potential DNA ... 64. In the
combined analysis of the nine microarrays, P values were
adjusted for multiple testing to control the false discovery rate
[13] or the type I family wise error ra...
... COPD in our study, in contrast to cur-
rent smokers, is supported by previous findings suggest-
ing that the inflammatory effects of current smoking may
mask the underlying o ngoing inflammatory ... only in ex-smokers, after the elimination of the
confounding role of continuing smoking.
In this study, we have used as a cut-off point for th e
expression of severe hype...
... Turk
1
and Robert H Dworkin
2
1
Department of Anesthesiology, University of Washington, Seattle, Washington, USA
2
Department of Anesthesiology, University of Rochester, New York, USA
Corresponding author: ... inherently
subjective. The only way to know about someone’s pain is
by what they say or show by their behavior. There is an
assumption that pain is highly associated with emot...
... mitigate against the
perfect management of pain in the ICU, the first step is to
measure the pain and to measure the response to initial
therapy. Without this measurement, all of the downstream
measures ... to
management of pain in the ICU is unclear. Opiates are used
routinely [13], but their usefulness as analgesics for different
ICU types of pain, their effects w...
... catalyze the synthesis
of a poly(A) chain in the absence of a primer [1]. In order
to explore whether the yeast enzyme also exhibited the
same properties we assayed, in parallel, the activity of
both ... independent synthesis of poly(A)
In order to understand why dinucleoside polyphosphates
activated the primer independent synthesis of poly(A), the
effect of...
... alue than
obtained by others [9]. T his may be due to the use of
homopolymeric rC-dG template in the assay. The assay
shows that PNU142721 is the most potent of the three
towards the K103N mutant ... Efavirenz.
Furthermore, wing2 composed of the heterocyclic ring
structure of MSC194 and the substituted pyrimidine
functionality of PNU142721 occupy the same p...
... slightly better’ or ‘much better’ than the
prestudy medication.
Safety and tolerability
Of the 245 subjects who were included in the safety
sample, 163 (66.5%) experienced an AE during the
switching ... subjects;
of these, 9 were judged as being unlikely to be related to
study drug, 14 as being unrelated to study drug, 11 a s
being possibly related to study drug, and 9 as bein...