... or tooearly or late in the course of their disease to have anyadvantageofAPC.Comparedtoarecentstudyof55patients with acute pancreatitis (with a 30-day morta lity of 27%) [37], the patients ... Organ-failure-free daysalive (ventilator-free days [22], renal replacement ther-apy-free days, va sopressor-free days), days alive outsidehospital in 60 days, and changes in other laboratoryvalues ... inci-dents of bleeding, and the primary efficacy endpoint was the change in SOFA between the start of the study drug(Day 0) and Day 5 [20,21]. Laboratory measurements for SOFA (serum creatinine,...