Báo cáo y học: "Argon neuroprotection" potx
Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx
... mirabilis G1 (Eur. J. Biochem. 269) 1409 Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 Zygmunt Sidorczyk1, Krystyna Zych1, Filip ... experi-ments. The following structure of the polysaccharide wasestablished:whereD-GalA6(L-Lys) stands for Na-(D-galacturonoyl)-L-lysine. The structure of the O-polysaccharide of P. mirabilis G1 ... LPS of P. mirabilis strains from two other serogroups contain-ingD-GalA6(L-Lys) in the O-polysacch aride or in the coreregion.Keywords: Proteus mirabilis; O-polysaccharide; lipopoly-saccharide;...
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Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx
... acid is located in the insert within the catalytic domain, close to the catalytic His264, and the proximity to the active site may explain the effect of oligomerization onenzyme activity. Even ... though the exact mechanism for complex formation and activation of the enzyme remainsto be determined, it can be concluded that the insert within the catalytic domain is of importance for oligome-rization.ACKNOWLEDGEMENTSThis ... wereformed by endogenous and recombinant monomers or if the a ctive complexes were assembled from the two types of homodimers. The insert within the catalytic domain is of importance for complex...
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Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx
... gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster Alla I. Kalmykova1, Yuri Y. Shevelyov1, Oksana O. Polesskaya1,*, Anna A. Dobritsa1,†,Alexandra ... of catalytic activity of a subunit towardcalmodulin and for the activation by polybasic compounds. The examination of amino-acid alignment in the acidicregion of three Drosophila CK2 regulatory ... (1993) Phosphorylation of calmodulin by the catalytic subunit of casein kinase II isinhibited by the regulatory subunit. Arch. Biochem. Bioph ys. 300, 26 5 27 0.1 426 A. I. Kalmykova et al. (Eur. J....
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Tài liệu Báo cáo Y học: Novel bradykinins and their precursor cDNAs from European yellow-bellied toad (Bombina variegata) skin potx
... defensive skin secretion of the yellow-bellied toad (B. variegata)andthesubsequent cloning of their precursor cDNAs from a skin- derived cDNA library. In addition, both peptides werechemically synthesized ... data on phyllokinin (braykinyl-isoleucyl-tyrosine-0-sulphate) and bradykinyl-isoleucyl-tyrosine. Br.J.Pharmacol.27, 479–485.16. Yasuhara, T., Hira, M., Nakajima, T., Yanaihara, N. &Yanaihara, ... This sensitivity is well within the capabilityof the ES-MS system employed.The primary structural diversity displayed withinamphibian skin bradykinins may not simply be due tophylogenetic differences...
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Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
... activity of CTP synthase (Eur. J. Biochem. 269) 4779 Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between ... lactis CTP synthase is suggested. Here the binding of GTP to the allosteric site promotes coordination of the phosphorylation of UTP and hydrolysis of glutamine foroptimal efficiency in CTP synthesis ... Lactococcus lactis. CTP synthase (EC 6.4.3.2) catalyzes the synthesis of CTP from UTP by amination of the pyrimidine ring at the 4-position. The enzyme has three functionally distinct sites; the glutaminase...
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Tài liệu Báo cáo Y học: Novel complexes of mammalian translation elongation factor eEF1AÆGDP with uncharged tRNA and aminoacyl-tRNA synthetase potx
... complexes of mammalian translation elongation factor eEF1AặGDP with uncharged tRNA and aminoacyl -tRNA synthetase Implications for tRNA channelingZoya M. Petrushenko, Tatyana V. Budkevich, Vyacheslav ... enzyme. A possiblerole of these stable novel ternary and quaternary complexes of eEF1AặGDP with tRNA and ARS in the channeled elongation cycle is discussed.Keywords: translation elongation factor; ... during mammalian translation elongation cycleRecently, the crystal structure of the [eEF1AặeEF1Ba]complex became available revealing a possibility of competition between tRNA/ aminoacyl -tRNA and...
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Tài liệu Báo cáo Y học: Characterization of a novel silkworm (Bombyx mori ) phenol UDP-glucosyltransferase potx
... project. A wing disc cDNA library derivedfrom fifth instar B. mori C108 larvae was kindly providedby Dr Kawasaki (University of Utsunomiya, Japan). A total of 1000 clones were s elected at random and ... 26 9) Ó FEBS 2002 Characterization of a novel silkworm (Bombyx mori ) phenol UDP-glucosyltransferase Teresa Luque1, Kazuhiro Okano2and David R. O’Reilly11Department of Biology, Imperial ... utilizationfor silk production.Here, we describe the isolation and characterization of a novel B. mori UDP-glucosyltransferase gene, Bmugt1,andanalysis of the activity of the enzyme towards a range...
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Tài liệu Báo cáo Y học: Kinetic study of sn-glycerol-1-phosphate dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix K1 potx
... were investigated, there hasbeen no kinetic study of the mechanism of this enzyme. Aeropyrum pernix K1 (JCM number 9820) is the first aerobic h yperthermophilic archaea for which the completegenome ... structuralrelationship to Gro dehydrogenases rather than Gro3 Pdehydrogenases [6].Cloning of Gro1P dehydrogenase from A. pernix The Gro1P dehydrogenase gene from A. pernix wasamplified by PCR with unique ... those of Gro1P dehydrogenases from archaea. The results are s ummarized in Fig. 1. The sequenceidentity for A. pernix Gro1P dehydrogenase to the Gro1P dehydrogenase from Methanobacterium thermoautotrophi-cum,...
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Tài liệu Báo cáo Y học: Divergent members of a soybean (Glycine max L.) 4-coumarate:coenzyme A ligase gene family potx
... gene family from Glycine max (Eur. J. Biochem. 269) 1315 Divergent members of a soybean (Glycine max L.) 4-coumarate:coenzyme A ligase gene family Primary structures, catalytic properties, and ... 5Â-CAACGGAAGCACGCATAGGAGCAC-3Â4CL16-SphI5Â-CACCGCATGCATAACTCTAGCTCCTTCTCTTG-3ÂSeq1 5Â-GTAAAACGACGGCCAGT-3Â1306 C. Lindermayr et al. (Eur. J. Biochem. 269) Ó FEBS 2002 4-coumarate and caffeate ... 5Â-TCYGGRTCRTTNAGRTADCCTTTCAT-3Â4CL1-S2 5Â-TBACNCARTCNGCNTAYGTBGARAA-3Â4CL3-HindIII 5Â-GTTCTAAGCTTTTAAGGCGTCTGAGTGGC-3Â4CL133ÂKpnI5Â-AGTTTCAGGGTCAACAACCCTG-3Â4CL13-EcoRI 5Â-CTCGAATTCATGACAACGGTAGCTGCTTCTC-3Â4CL14-BamHI...
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Báo cáo y học: "Propofol: neuroprotection in an in vitro model of traumatic brain injury" pot
... thenature of the model it excludes mechanisms of injury that mayinfluence brain damage in the in vivo situation such as theabsence of any injury pathways related or due to brain swellinginside an ... properties in an in vitro model of traumatic brain injury.Methods In this controlled laboratory study organotypichippocampal brain- slice cultures were gained from six- to eight-day-old mice ... used in combination, the dose-dependentneuroprotective effect of propofol is additive to theneuroprotective effect of hypothermia in an in vitro model of traumatic brain injury.IntroductionTraumatic...
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Báo cáo y học: "Argon: Neuroprotection in in vitro models of cerebral ischemia and traumatic brain injury" pdf
... traumatic brain injury and stroke arewidespread and generate an enormous economic and socialburden, we investigated the possible neuroprotective effect in in vitro models of traumatic brain injury and ... effect in both in vitro models of oxygen-glucose deprivation and traumatic brain injury. Our promising results justify further in vivo animalresearch.IntroductionThe first biological effects of ... 1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, twomGlu1 receptor-preferring antagonists, reduce neuronaldeath in in vitro and in vivo models of cerebral ischaemia....
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Báo cáo y học: "Argon neuroprotection" potx
... evidence that argon may have therapeutic properties for neuronal toxicity by demonstrating protection against both traumatic and oxygen-glucose deprivation injury of organotypic hippocampal cultures ... cheaper, than xenon (the latter of which is currently in clinical trials for perinatal hypoxic-ischemic brain injury; TOBYXe; NCT00934700). We eagerly await in vivo data to complement the promising ... their current investigation, they demonstrate that argon is neuroprotective when applied after an oxygen-glucose deprivation (OGD) or traumatic injury in organotypic hippocampal slice cultures...
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Báo cáo y học: "Global ‘worming’" potx
... aretaking. On the premise that life on Mars may be ancestrallyrelated to life on Earth, they are attempting to identifypotential life by amplifying highly conserved ribosomalsequences (16S) from ... Laboratory of Neural Circuits and Behavior, HHMI/Rockefeller University, York Avenue, New York, NY 10021, USA.Correspondence: Sreekanth H Chalasani. Published: 13 September 2007Genome Biology 2007, ... http://genomebiology.com/2007/8/9/314â 2007 BioMed Central Ltd A report on the 16th International Caenorhabditis elegansMeeting, Los Angeles, USA, 27 June-1 July 2007.Held every other year at the University...
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Báo cáo y học: " Not debatabl" potx
... change, energy security, educa-tion and healthcare, all of which revolve around science?” Ifthey do, they’re not saying.What are they afraid of? One possibility, of course, is thatthey are all ... not by the overwhelming weight of the bestscientific evidence. We simply cannot have a strong, pro-tected democracy if our political leaders are scientificallyignorant, or if they only pay attention ... demand nearly alltheir attention, or they see scientific issues as the whining ofa small, specialized group that usually votes Democraticanyway, no matter what any candidate says.The argument...
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Báo cáo y học: "Meta-morphosis" potx
... is, “[mayGod] give you gentlemen a pleasant repose”). But now, by aprocess of metanalysis, merry is frequently construed as anordinary adjective modifying gentlemen (“God rest ye, merrygentlemen”) ... like this:OK, I know it’s not very funny, but how many funnychemistry jokes are there? Anyway, someone reminded meof this joke the other day and while I was busy not laughing Iwas also thinking ... sloppy mashing up of lots of bad data”. Finally,sometimes you actually may want to test the hypothesisacross ethnicity or age or other variables. In those instances,meta-analysis allows you...
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