... poten-tially harmful physiological abnormalities such as hyper-tension, tachycardia, cardiac arrhythmias or intracranialhypertension which were attributable to inadequate seda-tion should be made. ... Thus,what appears to medical and nursing staff to be an idealsedative agent, in particular more recently available short-acting anaesthetic agents which provide titratable seda-tion, but by nature ... must findways of accommodating clinical reality, not ignoring it. BMJ 1997,315:1109–1110.3. Barrientos-Vega R, Sanchez-Soria M, Morales-Garcia C, Robas-Gomez A, Cuena-Boy R, Ayensa-Rincon A: ...