Báo cáo y học: " Identification of restriction endonuclease with potential ability to cleave the HSV-2 genome: inherent potential for biosynthetic versus live recombinant microbicides" pdf
... cytosine but 5-hydroxymeth-
ylcytosine, and most of the hydroxymethylcytosine resi-
dues in these DNAs are glycosylated as well [20]. The
genome of the B. subtilis phage contains a diversity of ... with potential ability to
cleave the HSV-2 genome: inherent potential for biosynthetic
versus live recombinant microbicides
Misaki Wayengera*
1,2,3,4
, Hen...
... appeared to be
520
IYYPGE
525
,
because any deletion of residues from either end of
520
IYYPGE
525
destroyed the ability of mAb 1C8 to bin d.
Comparative analysis of the amino acid sequences of
the ...
DHPRGRSGGGDDDEAYYPGE
G A PAELPP
EPLRSRGGG DDEAYYPGE
G A PAELPP
DQDEPDA DYPYYPGE
ARGA PRGVDS
GRDEPDR DFPYYPGE
ARPE PRPVDS
DYDDRD DAPYYPGE
ARAP PRVVPDSGGRGR
DHDDRD DAAY...
... be necessary to address the
potential role of these genes in dorso-ventral patterning.
Tag-mapping to the genome and tags with no match to
transcript databases
The availability of the X. tropicalis ... mapped to transcripts with known dorso-ventral expression
and the frequency of appearance for these tags in each library is in agreement with the expression...
... file 3), the vast majority of random P-values
are uniformly distributed, indicating that they correspond
to the truly null hypothesis. Compared with the real case,
the set of artificial hotspot-SNP ... <0.01)
measured by: (1) the physical distance (in kilobases)
from the SNP to the center of the hotspo t; and (2) the
number of SNPs between the candidate SN...
... history,
and certain laboratory data may guide the choice of
which endoscopic investigation to perform first in
patients with IDA (especially in pre-menopausal
women), thereby, potentially ... assessment of patient
characteristics, clinical history, and certain laboratory
data may guide the choice of which endoscopic in -
vestigation to perform first in patients with I...
... Construction of cDNA Library in S. cerevisiae DSY-2 Strain
The cDNA library was prepared by transforming the
yeast S. cerevisiae DSY-2 strain, in which the cDNA
mixture was combined with pDL2-XN vector ...
5’-AAAACAGAGACCCATATGTAAATTGGTACCAATT-3’
The amplified PCR product was cloned into the
binding domain vector pTMBV4 in-frame with Cub (the
yeast ubiquitin). The cons...
... osteoarthritis, in accordance
with the terms of the Ethics Committee of the University of
Ulm. The age of the donors ranged from 55 to 89 years
(mean 74 years). The diagnosis was based on clinical ... fluorescence automated flow cytometry and cell sorting
using typical combinations of cell surface markers for
MPCs offer powerful tools with which to study the...
... antibody sub-
populations and by the variety of corresponding epitopes.
Recently, two polyclonal antibodies (SYM10, SYM11)
were generated that specifically bind to the symmetrical
form of dimethylarginine ... major
autoepitope within the carboxyl-terminus of SmD1 [21,22].
The aims of the present study were to develop a peptide-
based ELISA system for the detection o...
... this
study further confirms the autoimmune involvement in BD and
may provide new inroads into elucidating the immunopatho-
genesis of the disease. In an effort to clarify the association of
BD with ... performed the study and drafted the manuscript. PY pro-
vided technical help throughout the study. SLC and EMT con-
ceived the study, participated in the design and he...
... This contrasted with 19% of
patients with systemic lupus erythematosus and 15% of
patients with systemic sclerosis whose serum samples
reacted with both forms of α-enolase. They hypothesised that
RA ... likely to be present in myeloid cells, the domi-
nant cell type in the rheumatoid joint. We therefore studied the
promyelocytic HL-60 cell line, which can readily be diff...