Báo cáo y học: "Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients" pps

Báo cáo y học: "Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients" pps

Báo cáo y học: "Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients" pps

... triggers inflam- matory cascades involving as many as 14 distinct signaling pathways, including the NF-κB pathway. Interestingly, many of the genes in these pathways are regulated by the proteasome ... [8]. Viewpoint Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients Jan Brun 1,2,3 and Douglas A Gray 1,2 1 Ottawa Health...
Ngày tải lên : 13/08/2014, 16:21
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Báo cáo y học: "A new clinical rating scale for work absence and productivity: validation in patients with major depressive disorder" pot

Báo cáo y học: "A new clinical rating scale for work absence and productivity: validation in patients with major depressive disorder" pot

... ± 5.9, indicating a moderate severity of depression. The subjects missed an average of 10 hours of work in the past 2 weeks owing to their symptoms, which represented 16% of the time they were ... productivity subscale scores. Figure 1 shows the degree of clinical impairment (defined as percentage of the sample scoring 2 or higher on the item, indicating 50% or more...
Ngày tải lên : 11/08/2014, 17:20
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Báo cáo y học: " BODE index versus GOLD classification for explaining anxious and depressive symptoms in patients with COPD " pptx

Báo cáo y học: " BODE index versus GOLD classification for explaining anxious and depressive symptoms in patients with COPD " pptx

... scoring. Variables and point values used for the computation of the BODE index are shown in table 1. Finally after obtain- ing the BODE index for all patients, quartiles of the BODE index were used to ... classification for explaining these symptoms. Anxious symptoms were explained by dyspnoea. Depressive symptoms were explained by both dyspnoea and reduced exercise capac-...
Ngày tải lên : 12/08/2014, 14:20
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Báo cáo y học: "S-100B and neuron-specific enolase as predictors of neurological outcome in patients after cardiac arrest and return of spontaneous circulation: a systematic review" ppt

Báo cáo y học: "S-100B and neuron-specific enolase as predictors of neurological outcome in patients after cardiac arrest and return of spontaneous circulation: a systematic review" ppt

... analysis. Conclusions In such circumstances, the findings of the present study should aid future investigators in examining the clinical usefulness of these markers and determination of cut-off values. Introduction Identifying ... the process of aggravation of brain injury, while brain imaging, physical examination, and electrophysiology all focus on the consequences...
Ngày tải lên : 13/08/2014, 18:22
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Tài liệu Báo cáo Y học: Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase doc

Tài liệu Báo cáo Y học: Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase doc

... 2002 understanding of the function and organization of the enzyme complex, the analysis of mutant a lleles of the ge nes involved in the biosynthetic pathway c an certainly provide valuable information. In ... addition of Tween 40 [39], i t can be concluded that the 482 Gly residue is important for the activity of the enzyme, likely being one of the res...
Ngày tải lên : 22/02/2014, 04:20
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx

Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx

... otypic analysis (at the p rotein level), the f ew animals yielding in their milk the a s1 -CasM variant were exclusively heterozygous M/F a t the a s1 -Cas locus. There- fore, analysis o f their ... secondly impairs the phosphorylation of Ser64 in the M variant. The sequence determined is consistent with the molecular mass measured for the native protein. The phosp...
Ngày tải lên : 22/02/2014, 04:20
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Báo cáo y học: "Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease" ppsx

Báo cáo y học: "Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease" ppsx

... elusive. Relevance of the findings The question of whether our findings are of any significance for the understanding of CIJD is justified and needs answering. 1. Involving microbial infections as a leading ... cells in pathogen-induced chronic inflammatory joint diseases. Any inflammation will cause the induction of chemokine and cytokine production in several tissue...
Ngày tải lên : 09/08/2014, 01:23
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Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf

Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf

... phase of inflammatory arthritis [27,28]. Since the pro-apoptotic pro- tein Bid links the extrinsic to the intrinsic pathway, we exam- ined the affect of inducing experimental inflammatory arthritis in ... & Therapy Vol 9 No 3 Scatizzi et al. Page 4 of 10 (page number not for citation purposes) invasion of leukocytes, proliferation of synoviocytes resulting in the...
Ngày tải lên : 09/08/2014, 10:20
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Báo cáo y học: "Adherence with urate-lowering therapies for the treatment of gout" pps

Báo cáo y học: "Adherence with urate-lowering therapies for the treatment of gout" pps

... was involved in the analysis of data from this study and interpretation and presentation of results. RY was involved in the interpretation of the data, and drafting of this article. IO was involved ... adherence to newly-initiated ULDs was common in gout patients, with only 44% of the study pop- ulation achieving an MPR > 0.80 in the first year of therapy. Pre...
Ngày tải lên : 09/08/2014, 14:20
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Báo cáo y học: " Peripheral blood and neuropsychological markers for the onset of action of antidepressant drugs in patients with Major Depressive Disorder" pps

Báo cáo y học: " Peripheral blood and neuropsychological markers for the onset of action of antidepressant drugs in patients with Major Depressive Disorder" pps

... Germany. 2 Interdisciplinary Centre for Clinical Trials (IZKS), University Medical Centre, Mainz, Germany. 3 Clinic for Psychiatry and Psychotherapy, Katzenelnbogen, Germany. 4 Clinic for Psychiatry ... discussion of the results. Psychologists of the in the participating trial sites were trained in the application of the neuropsychological tests. At the beginning,...
Ngày tải lên : 11/08/2014, 16:23
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