... Toda, K., Takeda, K., Okada, T., Akira, S., Saibara, T., Kaname,T., Yamamura, K., Onishi, S. & Shizuta, Y. (200 1) Targeteddisruption of the aromatase P450 gene (Cyp1 9) in mice and their ovarian ... fromOriental Yeast (Tokyo, Japan). BPA and E2 were fromSigma-Aldrich. An ELISA kit for BPA was from TakedaPharmaceutical Co. Ltd. (Tokyo, Japan). All other chem-icals were of analytical grade.AnimalsAnimal ... 5Â-GCAAGAGCAGGCACCCAGCAACCAG-3Â and antisense primer: 5Â-TTCCGTCACATAAAACCACAGCACT-3 ), follicle stimulatinghormone (FSH) receptor (a 684-bp fragment with senseprimer: 5Â-TAGATGATGAACCCAGTTATGGAA-3Âand...