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Báo cáo y học: "Asthma is a risk factor for acute chest syndrome and cerebral vascular accidents in children with sickle cell disease" ppt

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Báo cáo y học: "Asthma is a risk factor for acute chest syndrome and cerebral vascular accidents in children with sickle cell disease" ppt

... CentralPage 1 of 5(page number not for citation purposes)Clinical and Molecular AllergyOpen AccessResearchAsthma is a risk factor for acute chest syndrome and cerebral vascular accidents in ... that recent and recurrent episodes of acute chest syndrome are risk factors for cerebral vascular accidents [10]. Our findings of increased cerebral vascular accidents in patients with sickle cell ... retrospective chart analysis was performed investigating 48 children ages 3–18 years with asthma and sickle cell disease and 48 children with sickle cell disease alone. Children were matched for age, gender,...
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Báo cáo y học: "SHROOM3 is a novel candidate for heterotaxy identified by whole exome sequencing" pptx

... TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCAAGCAGGTTGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCGAGCAGGTTGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC ... features include dextrocardia, L-transposition of the great arteries, abdominal situs inversus, bilateral (a) t TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC TCTCCCTCCAAGCAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCC ... heterotaxy and is consistent with a laterality disorder. In Xenopus, Shroom3 is expressed in the myocardium and is necessary for cellular morphogenesis in the early heart as well as normal cardiac...
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Báo cáo y học: "What is a virulence factor" pot

... Seguin M, Yuan L, Kelly N, Hammack C, SadoffJ, Gemski P Jr.: The importance of a lipopolysaccharide-initi-ated, cytokine-mediated host defense mechanism in miceagainst extraintestinally invasive ... antibodies directed against the Oantigens of Gram-negative bacteria are highly protective [7,8] and that many of the licensed vaccines against bacterialpathogens are directed against the capsular ... bacterial virulence factor by itself to initiate disease.Finally, the importance of the O antigen and capsularpolysaccharides as virulence determinants can be demon-strated by the fact that...
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Báo cáo y học: " FISH Oracle: a web server for flexible visualization of DNA copy number data in a genomic contex" ppsx

... 5(4):557-572.42. Sakakura C, Mori T, Sakabe T, Ariyama Y, Shinomiya T, Date K, Hagiwara A, Yamaguchi T, Takahashi T, Nakamura Y, Abe T, Inazawa J: Gains, losses, and amplifications of genomic materials in primary ... copy number dataincluding classical array CGH tiling microarrays or SNPmicroarrays. Although a number of software tools for array CGH analysis and visualization are available —both from academia ... for visualizing and analyzing array CGH data. Interestingly, except for waviCGH, all web-based software tools for array CGHdata analysis have been published in the mid-2000s.However, waviCGH,...
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Báo cáo y học: "Generation of a single pulmonary pressure-volume curve does not durably affect oxygenation in patients with acute respiratory distress syndrome" docx

... affect oxygenation in patients with acute respiratory distress syndrome Antoine Roch, Jean-Marie Forel, Didier Demory, Jean-Michel Arnal, Stéphane Donati, Marc Gainnier and Laurent PapazianService ... super syringetechnique.Variables were expressed as mean ± standard deviation. A two-way analysis of variance (ANOVA) for repeated measureswas conducted to study the effects of time and PV measure-ment ... a single staticPV measurement on gas exchange and haemodynamics; the PVmeasurements were taken using a super syringe and by usingthe constant flow method in patients with acute respiratorydistress...
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Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"

... study, performed the statistical analysis and Figure 4Eosinophil cell count and C-reactive protein level for comparison of systemic inflammatory response syndrome and infection (P < 0Eosinophil ... sampleswere drawn into green-top vacutainer tubes containing lithium-heparin as anticoagulant. Plasma CRP was also measured byimmunoturbidimetry using the analyzer Cobas Integra (RocheDiagnostics, ... mortalityrelated to sepsis conditions vary between 28% and 54%.Eosinopenia was a sepsis marker in our study. The study by Gil and colleagues in a department of internal medicine showedthat an inflammatory...
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Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"

... unleashing NMDA and AMPA excitotoxic injury. Thus a mecha-nism by which abnormal energy metabolism may have an influence on clinical ALS is through depletion of Vgf neuroprotection against ... Chakraborty TR, Tkalych O, Nanno D, Garcia AL, Devi LA, Salton SR. Quantification of Vgf- and pro-SAAS-derived pep-tides in endocrine tissues and the brain, and their regulation by diet and ... Acad Sci USA 2006; 103(39): 14584-14589. 16. Yamaguchi H, Sasaki K, Satomi Y, Shimbara T, Kageyama H, Mondal MS, Toshinai K, Date Y, Gonzalez LJ, Shioda S, Takao T, Nakazato M, Minamino N. Peptidomic...
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Báo cáo y học: "Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer" pdf

... predominantly in the primary tumor genome before initiation of metastasis [9]. In line with this hypothesis is the finding that distinct clonal cell populations in primary pancreatic carcinoma can ... bioinformatic analysis of array data. OP performed the breakpoint sequencing and analyzed the data. MT generated mate-pair libraries. IR performed SOLiD sequencing and generated fragment libraries. ... pairwise comparison of somatic variations in primary and metastatic samples indicated that many chromothripsis clusters, isolated rearrangements and point mutations are exclusively present in...
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Báo cáo y học: "Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human" pdf

... recent study also reported a relationship between T cell avidity and polyfunctionality, finding that high avid-ity HIV-specific T cells are typically polyfunctional and capable of mediating potent ... study and oversaw the analysis of theviral sequence data; and PB conceived of, designed and co-ordinated thestudy, contributed to data analysis and helped to draft the manuscript. Allauthors ... Briefly, HIV-1 RNAwas isolated from plasma using a QIAamp viral RNAmini kit (QIAGEN), and cDNA was synthesized fromreplicate plasma virus RNA preparations using Super-Script III reverse transcriptase...
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Báo cáo y học: " MDM2 is a novel E3 ligase for HIV-1 Vif" pot

... Shirakawa K, Takaori-Kondo A, Kobayashi M, Tomonaga M, Izumi T,Fukunaga K, Sasada A, Abudu A, Miyauchi Y, Akari H: Ubiquitina-tion of APOBEC3 proteins by the Vif-Cullin5-ElonginB-ElonginC ... University, 54 Shogoin-Kawaracho, Sakyo-ku, Kyoto 606-8507, Japan, 7Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan, 8Laboratory ... (activation-induced cytidine deaminase),APOBEC3 (A- H), and APOBEC4 [4]. A3 G is incorporatedinto HIV-1 virions and inhibits HIV-1 replication byinducing G-to -A hypermutation in viral cDNA duringreverse...
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