... within-study andbetween-study variation by incorporating the heterogeneity of effects in the overall analysis. ResultsA total of 2,093 articles were identified using the definedMedline search criteria, ... Rheumatology and Clinical Immunology, University of Maryland School of Medicine, 10 S. Pine St., MSTF 8-34; Baltimore, MD, 21201 USA4Division of Clinical Epidemiology, McGill University Health ... drugs act by directly modifying immu-nologic pathways involved in the pathogenesis of RA, it hasbeen of concern that their use may be associated with anincreased incidence of cancer. To better...