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Báo cáo y học: "Is cost-effectiveness analysis preferred to severity of disease as the main guiding principle in priority setting in resource poor settings" doc

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Báo cáo y học: "Is cost-effectiveness analysis preferred to severity of disease as the main guiding principle in priority setting in resource poor settings" doc

... preferred to severity of disease as the main guiding principle in priority setting in resource poor settings? The case of UgandaLydia Kapiriri*1, Trude Arnesen2 and Ole Frithjof Norheim1Address: ... and severity of disease as criteria for priority setting in health have shown a strong preference for severity of disease. Thesepreferences may differ in contexts of resource scarcity, as in ... Level of priority setting Consider priority setting as part of their workAge - NS ++ +Designation NS - ++ ++Level of priority setting ++ ++ - NSConsider priority setting as part of their...
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Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot

Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot

... extended to a cappingcycle of the nonacylated primary amine. After completion of the chain assembly, deprotection of the allyl esterwas performed manually by Pd(0) under Ar as previouslydescribed ... chemistryfor increasing the receptor affinity and selectivity of peptideligands [13,14,27]. The Ala-scan of OP has revealed that the side chain of each residue is required for the full activity of the ... cycliz-ation has been found to enhance the potency of peptides ontheir receptors [15 –18]. The aim of the present study was to prepare head -to- tail cyclic analogs of OP in order to generate possible...
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Báo cáo y học: "Is acute respiratory distress syndrome an iatrogenic disease" doc

... early identifi cation of the pulmonary in ammation associated with ALI.  e study was stopped prematurely after the second interim analysis (n = 150 patients) because investigators from one of ... Division of Critical Care Medicine, University of Toronto, Toronto, Canada5Adjunct Professor, King Saud University, Riyadh, Saudi ArabiaCompeting interests The authors declare that they have ... shown to increase alveolar-capillary leak, worsen oxygenation, cause pulmonary in ltrates, decrease lung compliance and cause an increase in lavage and systemic cytokines - all hallmarks of...
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Báo cáo y học: "Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development" potx

... rather technical issues that can be alleviated byincreasing the number of time points. This can be accom-plished by increasing the duration of the time course, the sampling frequency during the ... datasets were analyzed according to the parameters originally used for the Covington dataset; only genes common to the two microarray platforms were considered. (d) The Covington dataset was ... analysis of the combined Covington and Edwards datasets, as well as the Michael datasets. For the individual and combined Covington plus Edwards datasets, only genes that are expressed in both of...
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Báo cáo y học: "Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study" ppsx

... most of the gender differences in RA disease activitymay originate from the measures of disease activity rather thanfrom RA disease activity itself.Introduction The possible influence of gender ... were analyzed for American College of Rheumatology Core Data Set measures of disease activity,DAS28 (disease activity score using 28 joint counts), fatigue, the presence of rheumatoid factor, nodules ... VanderbiltUniversity, Nashville, TN; Yusuf Yazici, NYU Hospital for JointDiseases, New York, NY; Martin Bergman, Taylor Hospital,Ridley Park, PA; Christopher Swearingen, Medical University of South Carolina,...
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Báo cáo y học:

Báo cáo y học: "Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study" potx

... low levels of disease activity)one has to be cautious about interpretations of gender differ-ences since disease activity measures themselves may becontaminated by gender.Competing interestsOne ... Department of Internal Medicine and Clinical Immunology, Euroclinic of Athens, Athanasiadou 9, 11521, Athens, Greece14Department of Internal Medicine and Clinical Immunology, Euroclinic of Athens, ... therapies.Conclusions In this large multinational cohort, RA disease activity measures appear to be worse in women than in men.However, most of the gender differences in RA disease activitymay originate from the...
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Báo cáo y học: " Bilateral thalamic stroke due to occlusion of the artery of Percheron in a patient with patent foramen ovale: a case report" pot

... events. The posterior circulation was patent including the tip of the basilar artery and both posterior cerebral arteries, making the case compatible with occlusion of the artery of Percheron. Further ... passage of contrast bubbles from the rightauricle to the left cavities. Clot formation was found in the wall of the right auricle. The state of consciousness spontaneously resolved during the ... territory is the median part of the thalamusincluding the intralami nar nuclei and most of th edorsomedian nucleus. It is supplied by the paramedianarteries, usually emerging directly from the...
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Báo cáo y học: " A highly attenuated recombinant human respiratory syncytial virus lacking the G protein induces long-lasting protection in cotton rats" pot

... rRSV and ΔG in vitro, the absence of the G pro-tein resulted in an attenuated phenotype of the lattervirus in the cotton rat.Pulmonary inflammation was assessed using a scoringscale system comparable ... form of the G glycoprotein of respiratory syncytial virus. J Virol 1988, 62:2228-2233.10. Teng MN, Whitehead SS, Collins PL: Contribution of the respiratory syncytial virus G glycoprotein and ... severity of the lesions was incorporated. For each group the meanscore of each histopathological parameter was calculated.Since the scoring was non-linear, the histological datawere analyzed by...
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Báo cáo y học: "Electrical impedance tomography compared to positron emission tomography for the measurement of regional lung ventilation: an experimental study" pptx

... scan was made within 10 minutes. Then, the 13N-N2tracer continuously produced by the cyclotron fed the ventila-tor and was washed -in into the lungs through the endotrachealtube, and administered ... charge of the chemistry in the platform. FL is anengineer in charge of the PET camera. IF is a professor of physiology and was a visiting professor at the time of thisexperiment. CG is a professor ... at the very onset of inspiration and the tracer waswashed-out from the lungs. Emission scans were taken for fourminutes from the onset of washout to measure the tracer activ-ity inside the...
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Báo cáo y học: "Expression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination" ppsx

... breakpointlocation in the full alignment, but did not assign parentalsequences correctly (data not shown). In summary, the size of the dataset and the number of gap regions made the analysis very difficult ... loci either exist as provi-ruses or as solitary LTRs, the latter being the result of homologous recombination between the LTR's of a provi-rus, leaving one LTR behind. The source of evolutionarily ... represented in the humangenome assembly because of that.Discussion The nature of HML-2 sequences having formed evolution-arily young HML-2 proviruses in the human genomeremains speculative. Based...
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