Báo cáo y học: " Extending international sepsis epidemiology: the impact of organ dysfunction" pps

... greater organ dysfunction [2,10]. The evolution of organ dysfunctionthroughout the septic process provides us with criticalCommentary Extending international sepsis epidemiology: the impact of organ ... mortality both in the ICU and athospital discharge. Their study gives us insight into the impact of severe sepsis on organ dysfunction and mortality,although the study was conducted prior to the ... international epidemiology of severe sepsis. Taken together, these studiesconfirm that the sepsis incidence is high, that the development of organ dysfunction is a major determinant of mortality and that the occurrence...

Báo cáo y học: "An international sepsis survey: a study of doctors'''' knowledge and perception about sepsis" potx

... diagnose sepsis. Tachycardia was onlycited by 29%, leukocytosis or leukopenia by 20%, hypother-mia by 14%, and tachypnoea by 9% of physicians.Ability to diagnose sepsis and communicate about sepsis Four ... definitions of sepsis In general, physicians' definitions of sepsis were fragmented.When defining sepsis, only 22% (114 of 529) of the intensiv-ists and 5% (26 of 529) of the other physicians ... study is that there is a generalawareness of the importance and impact of sepsis among the physicians interviewed. A vast majority of physicians consider sepsis a leading cause of mortality....

Báo cáo y học: " Evidence-based practice implementation: The impact of public versus private sector organization type on organizational support, provider attitudes, and adoption of evidence-based practice" doc

... EBPs).Additionally, several of the study's primary hypothesesinvolve objectively measured criterion such as type of agency (i.e., public or private agency) which shouldexhibit minimal potential for systematic ... previous research by examining the association of organization type with level of organizational support forEBP. Third, the present study explores whether the level of tangible organizational support ... hypothesized model to the data. We assessedHypotheses five and six regarding partial mediation of organizational type by the level of organizational supportfor EBP, and mediation of organizational...

Báo cáo y học: "Theoretical basis to measure the impact of shortlasting control of an infectious disease on the epidemic peak" pps

... on the height and time of epidemic peak. The applica bility of our theoretical arguments is not restricted to the switch of con-trol policy. In many Northern hemisphere countries, the start of ... distribu-tion of the generation time [25].Sensitivity analysisIn addit ion to the analysis of empirical data, we a lso examine sensitivity of the heightand time of peak prevalence to different values of ... RO is financially supported by ResearchFellowship of Japan Society for the Promotion of Science.Author details1Department of Biology, Faculty of Sciences, Kyushu University, 6-10 -1 Hakozaki,...

Báo cáo y học: "he International Sepsis Forum’s controversies in sepsis: corticosteroids should be used to treat septic shock" doc

... at the 31st Annual Congress of the Society of Critical Care Medicine (SCCM), San Diego, California, USA,26–30 January 2002, and may not necessarily reflect the actual opinion of the author. The ... acuterespiratory distress syndrome. Older studies used largedoses for short periods of time, and were given early in the treatment – typically one or two doses of methylprednisolone (30 mg/kg). This was often ... http://ccforum.com/content/6/5/381In the early 1980s we were big proponents of usingcorticosteroids in septic shock, whereas in the late 1980s,following publication of the findings of the VeteransAdministration Systemic Sepsis...

Báo cáo y học: "Hemofiltration, adsorption, sieving and the challenge of sepsis therapy design" ppsx

... flexibility so the therapy may be tuned to patientbody size and severity of illness. This process begins withrecognition of key features of the inflammatory response. The network of IM, acting ... as a therapy for sepsis based on its ability to remove circulating IM by sieving orby adsorption, or both. Designing devices and methods for sepsis therapy will require optimization of these ... (e.g.filtration fraction: the so-called adsorption/synergistic effect).If hemofiltration is to be an effective therapy in the complexity of sepsis, then proper design of its material andoperational...

Báo cáo y học: "Memory-enhancing treatments reverse the impairment of inhibitory avoidance retention in sepsis-surviving rats" pdf

... consolidation depend on the integrity of the amygdala noradrenergic system [30] as do the enhancingeffects of NAL [31]. The effects of the noradrenergic systemon memory formation seemed to be ... one-trial inhibitory avoid-ance, and various forms of fear conditioning, all of whichclosely mimic human situations of daily life. The inhibitoryavoidance task relies heavily on the dorsal hippocampus ... the inhibition of some form of movement inresponse to sensory or other cues. Of the various training pro-cedures used, perhaps the most popular in the past few yearshave been the Morris water...

Báo cáo y học: "Bench-to-bedside review: The promise of rapid infection diagnosis during sepsis using polymerase chain reaction-based pathogen detection" pptx

... theseguidelines are the early diagnosis of infection as a cause for the patient’s systemic inflammatory response and the timelyadministration of appropriate antimicrobial chemotherapy. The consensus ... coverin the face of as-yet-unidentified infection because delayingantibiotic therapy in sepsis has been shown to increasemortality and morbidity [6,7]. Unfortunately, the widespreaduse of broad-spectrum ... antimicrobial therapy [1].While a number of clinical and technical factors may affect the isolation of the infecting organism [8], the volume of blood sampled is the most critical factor in the detection...

Báo cáo y học: " Can ‘permissive’ hypercapnia modulate the severity of sepsis-induced ALI/ARDS" doc

... pulmonary sepsis, suggesting that the eff ects of hypercapnic acidosis depend not only on the stage of the infective process, but also on the site of the primary infection.Early systemic sepsis Hypercapnic ... regarding the safety of hypercapnia in the setting of prolonged pneumonia, particularly in the absence of eff ective antibiotic therapy.Figure 2. Potential mechanisms underlying the e ects of hypercapnic ... Finally, buff er-ing of the acidosis induced by hypercapnia does not confer signifi cant benefi t in the setting of lung or systemic sepsis, and may actually worsen lung injury in the setting of...

Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique

... from the radiofrequency procedure, the length of im-provement varied from 3 months to 16 months. Again, no one in the radiofrequency group developed permanent relief of their pain. Thus, the ... being 5 months. The range of relief for the radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure. Of the 14 patients who revealed ... considering the endoscopic option. The facet injections in these 72 patients gave 50 to 100% relief of their pain in 86% of the patients with a median relief period of 3 months. The range of relief...

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