Báo cáo y học: " Amino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep retrovirus" potx

... activity of mouse Hyal2 in comparison to that of human Hyal2. We have mapped four of the amino acid residues that are important for human Hyal2 function as a virus receptor to a surface patch on the ... levels are at least as high as those of human Hyal2 following expression plasmid transfectionFigure 4Cell-surface mouse Hyal2 expression levels are at least as high as those of human Hyal2 following ... BioMed CentralPage 1 of 11(page number not for citation purposes)RetrovirologyOpen AccessResearch Amino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep...

Báo cáo y học: "Vasculature deprivation – induced osteonecrosis of the rat femoral head as a model for therapeutic trials" ppsx

... Kataoka Y, Hasegawa Y, Iwata H, Matsuda T, Genda E, Miura T, Taka-hashi H: Effect of hyperbaric oxygenation on femoral headosteonecrosis in spontaneously hypertensive rats. Acta OrthopScand ... normal, differentiating ratosteoblasts. J Cell Physiol 1999, 181:479-488.129. Yamashita T, Asano K, Takahashi N, Akatsu T, Udagawa N, Sasaki T,Martin TJ, Suda T: Cloning of an osteoblastic cell line ... immature and malleable bone at the early stagesafter necrosis, it is hypothesized that the rat femoral heads are forced into atypical shapes by protruding from theacetabulum, or by other as yet...

Báo cáo khoa học: Amino acid residues on the surface of soybean 4-kDa peptide involved in the interaction with its binding protein potx

... by amine coupling. The 43-kDa proteinsolution was passed through the ﬂow cells as an analyte.Interaction of ligand and analyte was detected in real time as a change in the SPR signal. The association ... completely clariﬁed.However, the 43-kDa protein from cotton has weakantifungal activity against Alternaria brassicicola and Bot-rytis cinerea [4]. As the 43-kDa protein is localized in plasmamembranes ... 167–172.8. Yamazaki, M., Takaoka, M., Katoh, E., Hanada, K., Sakita, M.,Sakata, K., Nishiuchi, Y. & Hirano, H. (2003) A possible phy-siological function and the tertiary structure of a 4-kDa peptidein...

Báo cáo y học: "Amino acid racemization reveals differential protein turnover in osteoarthritic articular and meniscal cartilages" docx

... 149:951-959.9. Helfman PM, Bada JL: Aspartic acid racemisation in dentine as a measure of ageing. Nature 1976, 262:279-281.10. Ohtani S, Matsushima Y, Kobayashi Y, Yamamoto Y: Age estima-tion by measuring ... of apparently undamaged OA articularcartilage was 35% to 38% lower than that of normal age-matched articular cartilage. This lower amino acid concentra-tion in normal-appearing articular cartilage ... articular cartilage. We also observed lower amino acid content in OA articular and meniscal cartilages comparedwith normal articular cartilage as well as a loss of total amino acids with age in...

Báo cáo y học: "Amino acid substitutions in the E2 glycoprotein of Sindbis-like virus XJ-160 confer the ability to undergo heparan sulfate-dependent infection of mouse embryonic fibroblasts" docx

... is an adaptation through the mutation for positively charged amino acid (aa), which frequentlyarise in laboratory strains during repeated passaging cul-ture, and that wild-type strains of SINV ... viral neurovirulence suggest that the two parameters are relatively separable, and that other properties of the virus play an important role for viral neurovirulence.Additional materialAdditional ... ofimmunofluorescence assay (IFA) and plaque assay indi-cated that XJ-160 virus was capable of assembling infec-tious particles in spite of different site-directed mutationat residue E2-146 or...

Báo cáo y học: "Amino acid size, charge, hydropathy indices and matrices for protein structure analysis" docx

... numbersindicating greater affinity for water [13].Molecules with similar hydropathy have affinity to eachother, they are compatible; molecules with differenthydropathy repel each other, and they are ... compatibilityin the amino acid bias: smaller residues preferentially co-locate with larger residues, while small-small and large-large co-locations are not preferred. This size preference at a ... plotted against SCI andHCI, and a more Gaussian distribution against CCI. This Amino acid co-locations vs. size, charge, and hydrophobe compatibility indexes in major subgroupsFigure 2 Amino acid...

Báo cáo y học: " The utility of the Historical Clinical Risk -20 Scale as a predictor of outcomes in decisions to transfer patients from high to lower levels of security-A UK perspective" pptx

... predominately male samples [6,11], there is relativelylittle data on female forensic or correctional samples.The vast majority of risk assessment studies in womenhave been based on psychopathy assessments ... This measure has 10 historical, relatively staticfactors that do not change over time, and 10 dynamic (5clinical and 5 risk management) items that are subjectto change with treatment. See table ... offenders: Appraising andmanaging risk Washington DC: American Psychological Association, 2 2006.50. Hare RD: The Hare Psychopathy Checklist-Revised Manual Toronto, Ontario:Multi-Health Systems...

Báo cáo y học: "Lassa virus-like particles displaying all major immunological determinants as a vaccine candidate for Lassa hemorrhagic fever" ppt

... mAbs, or goat PAb a- NP, and developed as described above.Lectin-based Glycan differentiation assaysGlycosylation patterns of VLP associated proteins werecharacterized via binding of glycan-specific ... performed for any member of the arenaviridae, it is likely that somecommon host cell proteins are packaged among a widearray of viral classes, and some of these proteins mayeven play functional roles ... systems to generate a Lassa virus (LASV)-like particle (VLP)-based modular vaccine platform.Results: A mammalian expression system that generated large quantities of LASV VLP in human cells at...

Báo cáo y học: " Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma" potx

... amounts ofGSH and GSSG were determined from a standard curveusing the authentic compounds as external standards.Statistical analysisData wer e analyzed using an analysis of variance and for post ... Cl2exposed animals. Impor-tantly, there was also evidence of a salutary treatmenteffect when DMTU was administered as late as 1 hourafter the exposure to Cl2suggesting that oxidativedamage is an ... release of relaxant substances such as NO or prosta-glandins [18-20]. The mechanism of AHR following Cl2may be similar to that of ozone in that both forms ofinjury are associate d with oxidant...

Báo cáo y học: " Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease" pptx

... as others have also adopted this strategy as a way forward in molecular analysis. Alagaratnam et al are utilising Bayesian approaches to pursue muscular dystro-phy diagnosis [223]. Similarly, ... 51(12):2333-2340.101. Okamoto M, Kawabe T, Iwasaki Y, Hara T, Hashimoto N, ImaizumiK, Hasegawa Y, Shimokata K: Evaluation of interferon-gamma,interferon-gamma-inducing cytokines, and interferon-gamma-inducible ... fingerprint is analysed, would increase theaccuracy of disease diagnosis, aid earlier disease detection,allow for improved clarification of disease subtypes andallow automation for community screening.Competing...

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