... developed the ESP methodology and BES mapping algorithms, analyzed the data and coordinated the clinical samples, sequencing, and experimental validation of ESP results. PY and CW inte-grated ESP ... clinical specimens and developed the FISH methods of breakpoint validation. JC, KJP, and GBMmanaged and selected the brain, prostate, ovary tumor sam-ples, respectively. PP, KB, YK, G-QH, and SS performedexperimental ... identity. If the BES hit multiple locations in the genome,then the position of the longest hit with highest identity waschosen and the BES was designated as being 'ambiguouslymapped' and...