Báo cáo y học: " Second site escape of a T20-dependent HIV-1

Báo cáo y học: " Second site escape of a T20-dependent HIV-1 variant by a single amino acid change in the CD4 binding region of the envelope glycoprotein" doc

... showed a single amino acid change A2 21V in the C2 region of gp120. This amino acid is highly conserved in natural sub- type B isolates [52], indicating that it plays an important role in Env ... con- tained identical escape variants with the same glycine-to- arginine substitution at position 431 of Env (all identical codon changes G GA-to-AGA). Glycine 431 is...

Ngày tải lên : 13/08/2014, 09:20

11
364
0

Báo cáo y học: "Protease inhibitor-induced nausea and vomiting is attenuated by a peripherally acting, opioid-receptor antagonist in a rat model" doc

... anti-HIV therapy as an adjuvant to other protease inhibitors because it inhibits the hepatic CYP 3A enzyme, thereby increasing the bioavailability and plasma concentration of other antiviral agents ... kaolin intake induced by ritonavir in ratsFigure 5 Effects of pretreatment with methylnaltrexone on kaolin intake induced by ritonavir in rats. Ritonavir-induced increase in...

Ngày tải lên : 10/08/2014, 05:21

8
320
0

Báo cáo y học: "Mortality associated with HIV-1, HIV-2, and HTLV-I single and dual infections in a middle-aged and older population in Guinea-Bissau" potx

... the statistical analyses. BH carried out the data management and data analyses and wrote the first draft. All authors contributed with interpretation of the data and to the final version of the paper. Acknowledgements This ... da Silva Z, Hedegaard K, Sandstrom A, Nau- cler A, Dias F, Melbye M, Aaby P: Prevalences of HTLV-1 infec- tion and associated risk determinants in...

Ngày tải lên : 13/08/2014, 05:22

9
336
0

Báo cáo y học: " Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays" pptx

... (indels) in the RSTA array data. Indels affected the Cy5 (non-digested) signal such that alleles with a deletion had a low binding signal (signal intensity <50), in the same range as background and ... observed in this study, depending on the polymorphism rate in the species and the number of individuals sampled in the study. The absence of ascertainment...

Ngày tải lên : 09/08/2014, 20:21

14
324
0

Báo cáo y học: "Eotaxin and FGF enhance signaling through an Extracellular signal-related kinase (ERK)-dependent pathway in the pathogenesis of Eosinophilic Esophagitis" doc

... this increase is also reflected systemically. In addition, the extent of increase in FGF and ERK pathways was closely associated with the sever- ity of the disease and endoscopic findings in the ... BLAST). Since the FGF-9 antibodywasmadeagainsttheentirelengthofthe amino acid, it is likely that homologous isoforms of FGF such as bFGF were also recognized. These da ta...

Ngày tải lên : 08/08/2014, 21:20

9
243
0

Báo cáo y học: " Patients with early rheumatoid arthritis exhibit elevated autoantibody titers against mildly oxidized low-density lipoprotein and exhibit decreased activity of the lipoprotein-associated phospholipase A2" pot

... IgG type against all types of oxLDL were determined by an ELISA method. The plasma levels of oxLDL and the Lp-PLA 2 activity were determined by an ELISA method and by the trichloroacetic acid ... selection of the patients and therapy. ECP contributed to the biochemical measurements and to writing the paper. AIP participated in the statistical analysis and in...

Ngày tải lên : 09/08/2014, 10:20

8
292
0

Báo cáo y học: " Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores" pptx

... Max MB: Use of the cumulative propor- tion of responders analysis graph to present pain data over a range of cut-off points: making clinical trial data more understandable. J Pain Symptom Manage ... RA, McQuay H: Single- patient data meta-analysis of 3,453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics. Pain 1997, 69:287-294. 16. Farrar J...

Ngày tải lên : 09/08/2014, 10:23

5
317
0

Báo cáo y học: "Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect" pdf

... analysis of cartilage repair by synovial mesenchymal stem cell transplantation in rabbitsIn vivo analysis of cartilage repair by synovial mesenchymal stem cell transplantation in rabbits. (a) ... repair Category Points Cell morphology Hyaline cartilage 4 Mostly hyaline cartilage 3 Mostly fibrocartilage 2 Mostly non-cartilage 1 Noncartilage only 0 Matrix-staining (metachromasia) N...

Ngày tải lên : 09/08/2014, 10:23

10
470
0

Báo cáo y học: " Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays" ppt

... nor- malization along with the intensity values of the two reference array hybridizations of Col-0 DNA. The log 2 ratio of the mean of the two intensities from the accession arrays over the mean of ... than 40 bp, and are characterized by hav- ing no short read coverage and a tile signal ratio below an arbitrary threshold. According to the analysis of the dis...

Ngày tải lên : 09/08/2014, 20:21

8
378
0

Báo cáo y học: "Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays" pps

... than 40 bp, and are characterized by hav- ing no short read coverage and a tile signal ratio below an arbitrary threshold. According to the analysis of the dis- tribution of the signal in each ... an independent approach and thus intersected our short read mappings with tiling array hybridizations. Using available tiling array data [12] and additional hybridizations, we determ...

Ngày tải lên : 09/08/2014, 20:21

8
394
0