Báo cáo y học: "The young, not-so-young, and the 2007 Retrovirology Prize: call for nominations" potx
Báo cáo y học: "The young, not-so-young, and the 2007 Retrovirology Prize: call for nominations" potx
... nominations and the selection processAs stated previously [4], the Prize alternates yearlybetween recognizing a non-HIV retrovirologist (2007 and odd years) and an HIV retrovirologist (2006 and evenyears). ... Lehming, and Robert K. Bell (Arlington,VA) 2007. 4. Jeang K-T: Life after 45 and before 60: the Retrovirology Prize. Retrovirology 2005, 2:26.5. Jeang K-T: Small philanthropy and big science: the ... RETROVI-ROLOGY prize and Stephen P. Goff. Retrovirology 2005, 2:43.6. Lever AML: Science – A life fully lived: Joe Sodroski wins the 2006 Retrovirology Prize. Retrovirology 2006, 3:45.7. Retrovirology...
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Báo cáo y học: "HLA-DR regulation and the influence of GM-CSF on transcription, surface expression and shedding
... study [22]. Sample preparation and flow cytometry Arterial blood was collected from septic patients on the day sepsis was diagnosed (day 0) and on days 3, 7, and 14 for PCR studies and days ... Microbiology and Immunology from University of Leeds, and PhD in Immunology from University of Liverpool, where she worked on the expression of HLA-DR and the characterisation of the monocyte in ... Director of BPL for his his help and support, the staff of the ITU at the RLUHT in particular the research nurses, Neal Gratton and Andrea Fazakerley for recruiting patients into the study. We would...
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Báo cáo Y học: Changes in ultrastructure and the occurrence of permeability transition in mitochondria during rat liver regeneration ppt
... in the mitochondrial and cytosolic fractions, and in the whole liver homogenate. The enzyme activity of mitochondrial AAT in the cytosol wasdetermined as described by Greco et al. [16]. Brie y, ... Ca2+movementduring the subfractionation technique. As preliminaryanalyses showed that there was no statistically significantdifference in the Ca2+content of mitochondria whether the buffers used for the ... or cytosolic proteins and are the means (± SEM) of five different preparations. The differencesbetween GDH and AAT activity in mitochondria and cytosols isolatedat 24 h after PH and the enzyme...
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Báo cáo y học: "Systemic lupus erythematosus and the type I interferon system" docx
... occurring SLE. The type I IFN system The type I IFN system comprises the inducers of type I IFNsynthesis, the type I IFN genes and proteins, the cells pro-ducing type I IFNs, and the target cells ... because they can provide direct evidence for the relevance of the type I IFN system in SLE and otherautoimmune diseases, and also provide more efficienttherapy.ConclusionWe have argued for a ... cells affected by the IFNs. The human type I IFN gene family contains a total of15 functional genes, 13 encoding IFN-α subtypes and oneeach for IFN-β and -ω [20]. The genes and their productshave...
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Báo cáo y học: "Analysis of C4 and the C4 binding protein in the MRL/lpr mouse" pptx
... planned and performed the majority of the experiments and was primary author of the manuscript. KS performed the hemolytic assays and assisted in interpreting the data.RAW generated the knockout ... In addition therewas no evidence of increased complement activation eitherlocally within the kidney or systemically in KO MRL mice at anyFigure 3Similar serum autoantibody titers and circulating ... interpreting the data, and critically reviewed the manuscript. MCBacquired funding, planned and supervised the experiments, and revised and edited the manuscript. All authors read and approved the final...
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Báo cáo y học: "Acute nerve compression and the compound muscle action potentia" doc
... during the recovery period.On the other hand, there are positive but statisticallyinsignificant correlations between the changes in velocityduring the 1st compression to 20 g and the amplitudereductions ... measuredby the force gauge, F is the force on the nerve and P is the pressure on the nerve. It should be noted that the com-pressed section of nerve is exposed to atmospheric oxygenthroughout the ... by a 3minute recovery period (3rd recovery). CMAP's wererecorded continuously during the entire periodStatistical analysis The term latency always refers to the time delay betweenthe...
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Báo cáo y học: "Acute nerve stretch and the compound motor action potential" potx
... accuracy. The specificity and sensitivity of the classifier for stage 8 ver-sus stage 1 is 100% and 84% respectively. When a lowstretch force is applied, the normalized velocity is the primary contributor ... computedfrom the onset latency and so reflects the velocity ofonly the most rapidly conducting axons. Also, becauseof the very short stimulus durations used, only the lar-gest and most rapidly conducting ... earlier points in the experiment.PredictabilityClinically, it is important to know what changes in the CMAP predict injury to the nerve and to know the sen-sitivity and specificity of these predictio...
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Báo cáo y học: " Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness" pot
... proper-ties of the lung tissues and that therefore it does not solelyreflect airway resistance. The sustained airway closure caused by NPFE wasreversible by deep inflation. Thus, for the assessment ... participated in the design of the study, the data acquisition and interpreta-tion, drafted the manuscript and revised it critically for scientific content. LGGparticipated in the conception of the extended ... respiratory mechanics. The mathematicalmodels used in the analysis of FOT data, specifically the constant-phase model [13], can provide valuable infor-mation pertaining to the heterogeneity of the...
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Báo cáo y học: "Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology" ppsx
... machinery, allowing the formation of glutathione (GSH) by the action of the rate-limiting enzyme, γ-glutamylcysteine synthetase (γ-GCS). The activity of γ-GCS is irreversibly blocked by L-buthionine-(S,R)-sulfoximine ... augmented by oxidative stress. Synthesized by the action of the rate-limiting enzyme γ-glutamylcysteine synthetase [47–50,107,108] glutathione uniquely provides a functional cysteinyl moiety that ... supporting the hypothesis that these metal atoms can sub-stitute for the iron atom within the heme moiety, and that the oxygen sensor for the induction of EPO is a heme protein [59–61,64,65]. Further...
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Báo cáo y học: "Hemofiltration, adsorption, sieving and the challenge of sepsis therapy design" ppsx
... sepsis and that provideoperational flexibility so the therapy may be tuned to patientbody size and severity of illness. This process begins withrecognition of key features of the inflammatory response. ... of 30–32% for polyamide and AN69, and of 0% for cellulose acetate and polysulfone. IL-1 adsorptionCommentaryHemofiltration, adsorption, sieving and the challenge of sepsistherapy designPatrick ... as a therapy for sepsis based on its ability to remove circulating IM by sieving orby adsorption, or both. Designing devices and methods for sepsis therapy will require optimization of these...
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