... signal-recognition particle (SRP). Furthermore, in vitrocross-linking experiments revealed that the G-10L mutantprotein is routed to the SecYEG translocon via the SRPpathway, the targeting pathway that ... protein, like that of the wild-type precursor, was strongly impaired in comparison with the processing in the wild-type strain(Fig. 2B). Apparently, substitution of the glycine residue atposition ... propose that this additional variable is a-helixpropensity. Apparently, the a-helix propensity of cysteinecompensates for its low hydrophobicity, resulting in a betterinteraction of the (G-10C)94PhoE...