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Báo cáo y học: "Recovery of fitness of a live attenuated simian immunodeficiency virus through compensation in both the coding and non-coding regions of the viral genome" pot

Báo cáo y học:

Báo cáo y học: "Recovery of fitness of a live attenuated simian immunodeficiency virus through compensation in both the coding and non-coding regions of the viral genome" pot

... labelled by nick-translation following stand-ard manufacturer's protocols (Roche, Indianapolis, IN, USA) and used in standard hybridization reactions.Western analysis of viral proteinAt ... virus through compensation in both the coding and non -coding regions of the viral genomeJames B Whitney1,2,3 and Mark A Wainberg*1,2Address: 1McGill University AIDS Centre, Lady Davis Institute-Jewish ... curves of variants har-boring compensatory mutations in the DIS (A4 23G), CA (K197R) and p6 (G49K) regions. C. Viral replication analysis of mutated viruses by TCID50 analysis of viral infectivity...
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Báo cáo y học: "Clinical review: Drotrecogin alfa (activated) as adjunctive therapy for severe sepsis – practical aspects at the bedside and patient identification Pierre-François Laterre and Xavier Wittebole" pdf

... dosage adjustment is indicated. Finally, the type and source of infection, and its anticipated natural history, may determine whether drotrecogin alfa (activated) is indicated as wellas the ... for the treatment of severe sepsis. APC has anti-coagulant activity by limiting thrombin formation and by inhibition of factors VIIIa and Va, and it promotes fibrinolysis by inhibitingplasminogen ... confi-dent in using heparin therapy were excluded from the study.As was anticipated, administration of drotrecogin alfa (acti-vated) was associated with an increased incidence of seriousbleeding...
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Báo cáo y học: "HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex" pdf

... overdu-plication. Embo J 2000, 19:2069-2081.43. Nakayama K, Nagahama H, Minamishima YA, Miyake S, Ishida N,Hatakeyama S, Kitagawa M, Iemura S, Natsume T, Nakayama KI:Skp2-mediated degradation of p27 ... (WT-Tax) or its equivalent carrying each of five mutant tax alleles and plated on agar plates containing 2% raffinose or 2% raffinose plus 2% galactose. The amino acid alterations in tax mutants ... with the senescence-like arrest may facilitate virus assembly and/ or transmis-sion. Many of the tax mutants characterized here thatremain functional in transactivating viral LTR and NF-κBcan...
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Báo cáo y học: "Aerosolised surfactant generated by a novel noninvasive apparatus reduced acute lung injury in rats" doc

... 1a) ;however, in the present experiment the anaesthetised rat wasplaced into a plastic container 30 minutes after the injection of OA. At the bottom of the container was a plastic plate, the anterior part ... phospholipids and about 1% hydrophobic protein,mainly surfactant protein B and C. It is approved for use in clin-ical trials of NRDS treatments by the State Food and DrugAdministration of China.Acute ... significantly lower in the PPS-inst and PPS-aer groups than in the other groups (P < 0.05; Table 2). In par-ticular, a reduction of intra-alveolar and interstitial oedema, and Figure 2Inhalation...
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Báo cáo y học: " Recovery of olfactory function after nine years of post-traumatic anosmia: a case report" pptx

... this case report and any accompanyingimages. A copy of the written consent is available forreview by the Editor -in- Chief of this journal.Competing interests The authors declare that they have ... post-traumaticolfactory loss might occur much later. We present a rare case of recovery from anosmia nine yearsafter the initial trauma.Case presentation: We report the case of a 54-year-old Caucasian man who ... 130:317-319.Do you have a case to share?Submit your case report today• Rapid peer review• Fast publication• PubMed indexing• Inclusion in Cases DatabaseAny patient, any case, can teach ussomethingwww.casesnetwork.comPage...
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Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"

... biologicplausibility and availability [8-25]. We measured PCT and proADM as markers of bacterial infection and inflamma-tion; the atrial-natriuretic peptide proANP and proET-1as markers of cardiac and ... the pathophysiology and prognosis of a disease process. As a quantifiable tool it facilitates risk stratification and moni-toring of therapy as a surrogate outcome measure. In the future, a panel of ... MW and BM drafted the manuscript. Allauthors amended and commented on the manuscript and approved the finalversion.AcknowledgementsWe thank our Data Safety and Monitoring Board, namely, A. P.Perruchoud,...
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Báo cáo y học: "An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report"

... important and patients who have had a previous attack of gout should bemade aware of common signs and symptoms, treatmentprotocols during an acute attack, and that gout may occur in any joint of ... onset of intensepain, redness and swelling of the joint. Examination willreveal a red, swollen, and extremely tender joint. Naturalhistory of an acute attack ranges from a few days to a few ... examination of choice forgouty arthritis although advanced imaging techniquesmay be used. The appearance of gout in MR imaging isvariable. Joint effusion and para-articular edema may bepresent...
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Báo cáo y học: "Clinical review: Treatment of new-onset atrial fibrillation in medical intensive care patients – a clinical framework"

... reportedsymptoms and by the days spent in the ICU and in the hospital. Haemodynamic parameters also tend to be worse in patients with AF. As for mortality, the causality of increasedmorbidity is hard ... Connolly SJ: Long-term amiodarone therapy and the risk of complications after cardiac surgery: results from the Canadian Amiodarone Myocardial Infarction Arrhythmia Trial(CAMIAT). J Thorac Cardiovasc ... placebo[91,94-97]. A meta-analysis showed that class IA, class IC and class III antiarrhythmic agents are equally effective in obtaining SR [98]. Meta-analyses comparing amiodaronewith class IC antiarrythmic...
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Báo cáo y học: "Spontaneous Hemoperitoneum Caused By a Diverticulum of the Sigmoid Colon"

... formed of the inner circular and outer longitudinal muscle layers. The vasa recta, which supply the mucosa and submucosa of the colon, penetrate the circular muscle. The weakness of the vascular ... normal, but the bowel preparation was poor. The invagination of diverticu-lum has an advantage over diverticulectomy in that it minimizes bowel leakage [15]. Moreover, invagina-tion of diverticulum ... the blood supply to the intestine. In the present case, blood supply to the intestine had to be preserved be-cause the patient had hemoperitoneum. In addition, the remaining colon wall was...
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Báo cáo y học: "Spindle Cell Lipoma of the Hypopharynx"

... approximately 0.6% of the laryngeal and hypopha-ryngeal benign tumors4. Laryngeal and hypopharyn-geal lipomas first appeared in literature in 1995 5. Laryngeal lipomas originate from adipose ... ex-pressed in liposarcomas. They are never expressed in lipomas and normal mature adipocytes. Typical ap-pearance of lipogenic tumors in the larynx and hy-popharynx are as submucosal yellowish ... solitary and slow-growing, and be-comes symptomatic at advanced stages of life. It usu-ally causes swallowing impairment, phonation prob-lems, the sensation of a lump in the throat, and rarely...
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