... set, the average size of the deleted domain was calculated for the proteins with the complete arrangement. To take into account the variability of the length of the complete domain, the length of ... each of the events, e, and for each of the sets of clus-ters of a given length, l, the frequency of the event at aposition, k, was defined as:fe;k¼ ne;k=Xli¼1ne;i;where ne,iis the ... the N-terminal fragment was definned as the length of the amino acid sequence preceding the next domain in the arrangements, expressed as the percentage of the calcu-lated average length of the...