Báo cáo khoa học: "The low-dose ACTH test in the ICU: Not ready for prime time" ppsx
Báo cáo khoa học: "The low-dose ACTH test in the ICU: Not ready for prime time" ppsx
... insufficiency in patients with septic shock, including the 250 µg ACTH stimulation test (standard or “high- dose” test) , the 1 µg ACTH stimulation test ( low-dose test) , measurement of random cortisol ... test in the ICU: Not ready for prime time Makito Yaegashi1 and Arthur J. Boujoukos2 1 Clinical Fellow, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, ... compare a low-dose (1 µg) adrenocorticotropic hormone (ACTH) stimulation test with the more standard (250 µg) test for the diagnosis of relative adrenal insufficiency. Methods Design and setting:...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... longer incubationperiods. Interestingly, the interruption of TAG synthe-sis preceded the appearance of toxic effects, supporting the notion that it constitutes the initiating event in the process ... divided in two phases according to the intensityand the duration of the stress. An initial adaptiveresponse culminates in the temporary inhibition ofprotein synthesis, providing cells with the ... effect was attributed to the formation of gel-like domains (instead of liquid-crystalline domains) in the membranes, making thesemolecules unavailable for the required interactions[30,33]. Addition...
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Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc
... take into account the variabilityof the length of the complete domain, the length of the N-terminal fragment was definned as the length of the amino acid sequence preceding the next domain in the ... autonomously. Therefore, weProDom, N−terminus ProDom, C−terminusLength of the N terminus in % of the deleted domainLength of the C terminus in % of the deleted domainPfam, N−terminus Pfam, C −terminusNumber ... domain deletions are more com-mon at either of the protein termini, and that theiroccurrence is slightly higher at one of the termini,depending on the number of domains in the proteinand the...
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Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx
... carbinolamine intermediate;III, iminoquinone intermediate; IV, product Schiff base intermediate;V, aminoquinol intermediate. In the oxidative half-reaction the ami-noquinol intermediate is ... XhoI site in the 3¢-end. The amplification product was cloned into the TAcloning vector PCR4-TOPO (Invitrogen, Carlsbad, CA) for sequencing and then subcloned into vector pCDNA II (In- vitrogen) ... pH; Fig. 4C). The more acidic ionization in the freeenzyme of pKa7.1 has a substantial affect on the affin-ity of the enzyme for substrate. In the protonatedform, the Kd for the enzyme substrate...
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Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt
... of PDZ binding on the interactions of the Grb4-SH2domain with the ephrinB2(301–333)-pY304 peptide. (A) The PDZ-binding curves are for the fluorescein-labeled peptides including eph-rinB2(301–333) ... determining the binding specificity towards phosphopeptides. For example, the b-sheet structure after the EF3 segment in the Src SH2does not exist in the Grb4 SH2 domain while the insertionafter the ... positioning of the Tyr304 residue for binding to tyrosine kinases and phos-phatases. On the other hand, tyrosine phosphorylations do not affect the conformation of the PDZ binding motif at the C-terminus...
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Tài liệu Báo cáo khoa học: Human intrinsic factor expressed in the plant Arabidopsis thaliana doc
... Aarhus, DenmarkIntrinsic factor (IF) is the gastric protein that promotes the intestinal uptake of vitamin B12. Gastric IF from animalsources is used in diagnostic tests and in vitamin pills.However, ... significantlylower for the plant source. In addition, the purificationtechnique for IF from plants was simpler due to expressionof the protein in the unsaturated apo-form in contrast with the B12saturated ... those obtained for human gastric IF in termsof the IF–CblOH2spectrum, the relative affinity to Cbl or the analogue Cbi, and the binding to the IF receptor cubilin.Comparison between recombinant...
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Tài liệu Báo cáo khoa học: "THERE STILL IS GOLD IN THE DATABASE MINE" potx
... and mine it very deeply, not necessarily discovering every aspect of the domain but requiring that the various aspects be integrated with one another to produce a coherent whole. Even in the ... its worth by the number of papers published and panels held on the subject. Indeed, it has been so deeply mined that the thought "Oh, no! Not another panel on natural language interfaces ... officers represented in it. The system merely made no distinction between "all" and "any", and interpreted the final query to mean the But, you are probably thinking, those examples...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... suggestingthat these cyclin-dependent kinase inhibitors areimportant in the regulation of adipocyte number. The S-phase kinase-associated protein (Skp)1–Cullin-F-box protein (SCF) ubiquitin ligase ... progression in mam-mals is governed at each phase of the cell cycle byvarious complexes of cell-cycle-related molecules,including cyclins, cyclin-dependent kinases, their inhib-itors and the retinoblastoma ... energy in the form ofintracellular triacylglycerol droplets in adipose cells,leading to an increased fat mass and ultimately result-ing in obesity.Adipocyte hyperplasia (increase in cell number)...
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Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx
... survivalwas not markedly compromised by the inhibition ofPI3K signaling with LY294002 in a fully supplementedmedium and within the tested time period (Fig. 3B, D).QDs induce the formation of LDs in ... stopper into eachflask with a syringe, and the flasks were then shaken gently for 24 h at room temperature. The filters were thenremoved and placed into scintillation vials containing scin-tillation ... causeoxidative stress and ⁄ or the release of specific cytokinesare potentially hazardous and are the prime candidates for LD induction. The majority of in vitro tests designed for the assess-ment of NP...
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Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx
... induced in the HMG box seems very interesting. Indeed, the bend determined by Raman for the free SREfos in solution is roughly similar to that formed in SREfos in the crystal of its complex with the ... and a linearform keeping the same average conformations. Thus,an increase in temperature displaces the equilibrium,increasing the amplitude of motion around the regularstates within the frame ... does not provide information on the localrepartition of the angles involved in the SREfoshelixbending.Relative effect of bending strainThere are several indications of a redistribution ofthe...
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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Báo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP