... whichdepends on the amount of inoculum, the route of infection and the geneticpredisposition of the infected subject [Hilton DA (2006) J Pathol 208, 134–141]. Therefore, there is a great need for effective ... demonstrated the trans-missibility of the bovine spongiform encephalopathy to humans [Beekes M(2007) FEBS J 274, 575]. Therefore, the spread of bovine spongiformencephalopathy across Europe and the ... in Ireland, three in the USA, two in the Netherlands and one each in Italy, Canada, Japan,Saudi Arabia, Portugal and Spain. Most of the patients from these countries resided in the UK during a...