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Báo cáo y học: "Attending to the lightness of numbers: toward the understanding of critical care epidemiology" ppsx

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Báo cáo y học: "Bench-to-bedside review: The MET syndrome – the challenges of researching and adopting medical emergency teams"

... systems ina rigorous and clinically relevant way.Evaluating the medical emergency team system Medical technologies and drugs are assessed usingmethodology favouring the statistical power of ... studyfrom the UK [6] which found that, prior to intensive care unit(ICU) admission, suboptimal management of oxygen therapy,ReviewBench-to-bedside review: The MET syndrome the challenges of researching ... 86.1% of these [45]. Interestingly, inthat study, 17.8% of all recordings of early signs and 9% of late signs were judged by nurses to be ‘usual for the patient’.These commonly included mild hypoxaemia,...
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Báo cáo y học: "introduction to special issue on Eye and Zoonosis – from the guest editors"

... Coherence Tomography in ocular toxoplasmosis ã Usefulness of vitrectomy in the treatment of ocular toxoplasmosis ã Update on the treatment of ocular toxoplasmo-sis. We hope that this special issue ... Journal of Ophthalmology: Delair E, Monnet D, Grabar S, Dupouy-Camet J, Yera H, Brézin AP. Respective roles of acquired and con-genital infections in presumed ocular toxoplas-mosis. Am J Ophthalmol ... be interesting to readers and provides researchers with timely up-date on various topics in this important field. Conflict of Interest The authors have declared that no conflict of in-terest...
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Báo cáo y học: "Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis" ppsx

... rheumatologist answered a questionnaireinquiring about the initial symptoms as reported by the patient(type of initial joint symptoms, localization and distribution of initial joint symptoms, ... articleAntibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritisAnnette HM van der Helm-van Mil, Kirsten N Verpoort, Ferdinand C Breedveld, René EM Toes and Tom ... expression of citrullinated proteins, but mightbe the result of an abnormal humoral response. Intriguingly,this antibody response may occur years before any clinical symptoms, as shown by the presence...
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Báo cáo y học: "Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro" pptx

... and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitroHenning Voigt, Angelika K Lemke, Rolf Mentlein, Michael Schünke and Bodo ... aggre-canase activity might be involved in the early TNFα -mediated aggrecanolysis in the meniscus. Inhibition of aggrecanase activity or TNFα -activity might therefore help to prevent menis-cal destruction. ... tissues can be mediated by both the production of NO and the involvement of matrix-degrading enzymes. We there-fore studied the influence of the NO-synthetase inhibitor L-NMMA on meniscal tissue....
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Báo cáo y học: "Provider-initiated HIV testing in rural Haiti: low rate of missed opportunities for diagnosis of HIV in a primary care clinic" ppsx

... uptake of HIV testing and minimal delaybetween first medical encounter and diagnosis of HIV infection. In scale up of HIV care, provider-initiated HIV testing at primary care clinics can be a ... care in central Haiti by reinforcing primary care clinics, instituting provider-initiated HIV testing and by providing HIV treatment in thecontext of primary medical care, free of charge to patients. ... purposes)AIDS Research and TherapyOpen AccessShort reportProvider-initiated HIV testing in rural Haiti: low rate of missed opportunities for diagnosis of HIV in a primary care clinicLouise...
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Báo cáo y học: "hytol-based novel adjuvants in vaccine formulation: 2. assessment of efficacy in the induction of protective immune responses to lethal bacterial infections in mice" ppsx

... purposes)Journal of Immune Based Therapies and VaccinesOpen AccessOriginal researchPhytol-based novel adjuvants in vaccine formulation: 2. assessment of efficacy in the induction of protective immune responses ... administeredintraperitoneally at 10-day intervals. The efficacy of the phytol and PHIS-01, as compared to IFA,was assessed by ELISA in terms of anti -bacterial antibody and inflammatory cytokines. We alsoexamined the ... anti- Efficacy of adjuvants in sustaining antibody response inducedFigure 2 Efficacy of adjuvants in sustaining antibody response induced. BALB/c mice in groups of 4 or more were immunized at day...
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Báo cáo y học: "Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis" pdf

... 13:R108http://arthritis-research.com/content/13/3/R108Page 5 of 7 RESEARCH ARTICLE Open AccessDisease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid ... Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis. Arthritis Research &Therapy 2011 ... importantpredictors of the number of hospital admissions and length of hospitalisation in RA. The combination of lifestylechanges, particularly increased physical activity along with effective pharmacological...
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Báo cáo y học:

Báo cáo y học: "Attending to the lightness of numbers: toward the understanding of critical care epidemiology" ppsx

... denominator and explored the effects of a changingnumerator according to the residency status on the estimation of the burden of admission to the ICU. Had the investigator ignored where the admitted ... for severity of illness. The epidemiology of critical care is influenced by the factorsthat affect decisions to admit patients to the ICU. We knowthere is tremendous variability in these decisions. ... linked to the healthservices research (scientific study of the organization, delivery,and financing of health care) of critical care. The influence of organizational features of the ICU on critical care...
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Báo cáo y học: " Corticosteroids to prevent postextubation upper airway obstruction: the evidence mount" doc

... volume) to define andstudy patients at high risk for postextubation UAO. Patientsrandomly assigned to methylprednisolone (40 mg every6 hours for four doses) were less likely either to experiencestridor ... than36 to 48 hours receive such therapy? Although a shortcourse of corticosteroids may be relatively safe, further studyis warranted. This author believes the focus should continue to be on ... the ETT. Alternatively, with the cuff deflated, the patient may breathe additional tidal volumearound the tube (in addition to machine delivered volume),leading to a falsely low measurement of...
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Báo cáo y học: " Bench-to-bedside review: High-mobility group box 1 and critical illnes" pdf

... p53 and p73 [11 ].The cytokine-like role of high-mobility group box 1 In 19 99, Wang and colleagues [12 ] identified HMGB1 as acytokine-like mediator of lipopolysaccharide (LPS)-inducedmortality ... http://ccforum.com/content /11 /5/229Abstract High-mobility group box 1 (HMGB1) is a DNA-binding protein thatalso exhibits proinflammatory cytokine-like activity. HMGB1 ispassively released by necrotic cells and also ... HMGB1 secretion, suchReview Bench-to-bedside review: High-mobility group box 1 and critical illnessMitchell P FinkDepartments of Critical Care Medicine, Surgery and Pharmacology, University...
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Báo cáo y học: "Bench-to-bedside review: Developmental influences on the mechanisms, treatment and outcomes of cardiovascular dysfunction in neonatal versus adult sepsis" ppt

... in the treatment of a variety of illnesses in all agegroups, but only a handful of studies have focused on the use of pentoxifylline in the treatment of sepsis in adults and neonates [93]. In ... primarily eliminated in the renal system.This impact is pertinent in milrinone use, and therefore dosingis often renally adjusted in neonates. In cases of persistentpulmonary hypertension of the newborn ... dysfunction and sequelae during infection and inflammation [14]. Underlyingdifferences in cardiovascular anatomy, function and responseto treatment may further alter the neonate’s response topathogen...
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Báo cáo y học: "Bench-to-bedside review: Candida infections in the intensive care unit" ppsx

... (wounds, surgery, andinsertion of indwelling intravascular and urinary catheters). The gastrointestinal tract, the skin and the urogenital tract are the main portals of entry for Candida infections. ... [18]. In ICU patients, the most common types of Candida infections are bloodstream infections, catheter-related infec-tions, intra-abdominal infections and urinary tract infections [19-23]. Invasive ... advances in ourunderstanding of the epidemiology, diagnosis and management ofinvasive candidiasis, which is the predominant fungal infection in the intensive care unit setting. Candida spp. are the...
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Báo cáo y học:

Báo cáo y học: "Bench-to-bedside review: Mobilizing patients in the intensive care unit – from pathophysiology to clinical trials" pot

... loss in the critically ill patient. Importantly,ReviewBench -to- bedside review: Mobilizing patients in the intensive care unit from pathophysiology to clinical trialsAlex D Truong1, Eddy Fan1, ... anti-inflam-matory cytokines during moderate exercise may play animportant role in muscle preservation and protection.Physical therapy in the intensive care unit Physical therapy practices vary greatly ... improving rehabilitation in the ICU. Indeed, the need for early activity in critically ill patients was recently reinforced by European guidelines forphysiotherapy in the ICU [68].A multidisciplinary...
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Báo cáo y học: "Bench-to-bedside review: Delirium in ICU patients - importance of sleep deprivation" doc

... Kribbs NB: Performing while sleepy: effects of experimentally-induced sleepiness. In Sleep, Sleepiness andPerformance. Edited by Monk TH. New York: J Wiley; 1991:9 7- 128.13. Harrison Y, Horne JA: ... with3,4-dihydroxy-L-phenylalanine and opiates, cocaine binges,and hypoxia [40]. Activation of the dopaminergic system isalso observed after periods of sleep deprivation [41].The mechanism of delirium ... lies in its potential as anothertarget for intervention to prevent acute ICU delirium. ReviewBench-to-bedside review: Delirium in ICU patients - importance of sleep deprivationGerald L Weinhouse1,...
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Báo cáo y học: " Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection" ppt

... Franks NP: Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection. Critical Care 2010, 14:229.Dickinson and Franks Critical Care 2010, ... an interesting possibility.Conclusions e present review summarizes studies on the pharmacology and clinical uses of the inert gases as anesthetics and neuroprotectants. Xenon is the only inert ... protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo. Anesth Analg 2007, 105:562-569.14. Yarin YM, Amarjargal...
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