... France2Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada3Department of Medicine, University of Toronto, Toronto, CanadaCorresponding author: Djillali ... [28,29]. To date, there are nonatural history data in sepsis patients to help us understandhow the magnitude of cortisol levels varies during theepisode of critical illness and in response to a ... administration of steroids for septic shock isappropriate. The results of the ongoing EuropeanCORTICUS study (Corticosteroid Therapy of Sepsis and Septic Shock) will hopefully provide some answers to theseimportant...